Refinement of Multiconformer Ensemble Models from Multi-temperature X-ray Diffraction Data

por Du, Siyuan, Wankowicz, Stephanie A., Yabukarski, Filip, Doukov, Tzanko, Herschlag, Daniel, Fraser, James S.
Publicado 2023

Ligand binding remodels protein side-chain conformational heterogeneity

por Wankowicz, Stephanie A, de Oliveira, Saulo H, Hogan, Daniel W, van den Bedem, Henry, Fraser, James S
Publicado 2022

Uncovering Protein Ensembles: Automated Multiconformer Model Building for X-ray Crystallography and Cryo-EM

por Wankowicz, Stephanie A., Ravikumar, Ashraya, Sharma, Shivani, Riley, Blake T., Raju, Akshay, Hogan, Daniel W., van den Bedem, Henry, Keedy, Daniel A., Fraser, James S.
Publicado 2023

Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma

por Bellmunt, Joaquim, Lalani, Aly-Khan A., Jacobus, Sussana, Wankowicz, Stephanie A., Polacek, Laura, Takeda, David Y., Harshman, Lauren C., Wagle, Nikhil, Moreno, Irene, Lundgren, Kevin, Bossé, Dominick, Van Allen, Eliezer M., Choueiri, Toni K., Rosenberg, Jonathan E.
Publicado 2018

Targeted genomic landscape of metastases compared to primary tumours in clear cell metastatic renal cell carcinoma

por de Velasco, Guillermo, Wankowicz, Stephanie A., Madison, Russell, Ali, Siraj M., Norton, Craig, Duquette, Audrey, Ross, Jeffrey S., Bossé, Dominick, Lalani, Aly-Khan A., Miller, Vincent A., Stephens, Philip J., Young, Lauren, Hakimi, A. Ari, Signoretti, Sabina, Pal, Sumanta K., Choueiri, Toni K.
Publicado 2018

Genomic Resistance Patterns to Second-Generation Androgen Blockade in Paired Tumor Biopsies of Metastatic Castration-Resistant Prostate Cancer

por Han, G. Celine, Hwang, Justin, Wankowicz, Stephanie A.M., Zhang, Zhenwei, Liu, David, Cibulskis, Carrie, Gaviola, Glenn C., Ghazikhanian, Varand, McKay, Rana R., Bubley, Glenn J., Carter, Scott L., Balk, Steven P., Hahn, William C., Taplin, Mary-Ellen, Van Allen, Eliezer M.
Publicado 2017

The long tail of oncogenic drivers in prostate cancer

por Armenia, Joshua, Wankowicz, Stephanie A.M., Liu, David, Gao, Jianjiong, Kundra, Ritika, Reznik, Ed, Chatila, Walid K., Chakravarty, Debyani, Han, G. Celine, Coleman, Ilsa, Montgomery, Bruce, Pritchard, Colin, Morrissey, Colm, Barbieri, Christopher E., Beltran, Himisha, Sboner, Andrea, Zafeiriou, Zafeiris, Miranda, Susana, Bielski, Craig M., Penson, Alexander V., Tolonen, Charlotte, Huang, Franklin W., Robinson, Dan, Wu, Yi Mi, Lonigro, Robert, Garraway, Levi A., Demichelis, Francesca, Kantoff, Philip W., Taplin, Mary-Ellen, Abida, Wassim, Taylor, Barry S., Scher, Howard I., Nelson, Peter S., de Bono, Johann S., Rubin, Mark A., Sawyers, Charles L., Chinnaiyan, Arul M., Schultz, Nikolaus, Van Allen, Eliezer M.
Publicado 2018

Cryo-EM model validation recommendations based on outcomes of the 2019 EMDataResource challenge

por Lawson, Catherine L., Kryshtafovych, Andriy, Adams, Paul D., Afonine, Pavel V., Baker, Matthew L., Barad, Benjamin A., Bond, Paul, Burnley, Tom, Cao, Renzhi, Cheng, Jianlin, Chojnowski, Grzegorz, Cowtan, Kevin, Dill, Ken A., DiMaio, Frank, Farrell, Daniel P., Fraser, James S., Herzik, Mark A., Hoh, Soon Wen, Hou, Jie, Hung, Li-Wei, Igaev, Maxim, Joseph, Agnel P., Kihara, Daisuke, Kumar, Dilip, Mittal, Sumit, Monastyrskyy, Bohdan, Olek, Mateusz, Palmer, Colin M., Patwardhan, Ardan, Perez, Alberto, Pfab, Jonas, Pintilie, Grigore D., Richardson, Jane S., Rosenthal, Peter B., Sarkar, Daipayan, Schäfer, Luisa U., Schmid, Michael F., Schröder, Gunnar F., Shekhar, Mrinal, Si, Dong, Singharoy, Abishek, Terashi, Genki, Terwilliger, Thomas C., Vaiana, Andrea, Wang, Liguo, Wang, Zhe, Wankowicz, Stephanie A., Williams, Christopher J., Winn, Martyn, Wu, Tianqi, Yu, Xiaodi, Zhang, Kaiming, Berman, Helen M., Chiu, Wah
Publicado 2021

A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing

por Gordon, David E., Jang, Gwendolyn M., Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M., O’Meara, Matthew J., Rezelj, Veronica V., Guo, Jeffrey Z., Swaney, Danielle L., Tummino, Tia A., Huettenhain, Ruth, Kaake, Robyn M., Richards, Alicia L., Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J., Braberg, Hannes, Fabius, Jacqueline M., Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J., Cakir, Merve, McGregor, Michael J., Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Kain, Alice Mac, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T., Melnyk, James E., Chorba, John S., Lou, Kevin, Dai, Shizhong A., Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher J.P., Perica, Tina, Pilla, Kala B., Ganesan, Sai J., Saltzberg, Daniel J., Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B., Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A., Bohn, Markus, Safari, Maliheh, Ugur, Fatima S., Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O’Neal, Michael C., Cai, Yiming, C.J.Chang, Jason, Broadhurst, David J., Klippsten, Saker, Sharp, Phillip P., Wenzell, Nicole A., Kuzuoglu, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M., Cavero, Devin A., Hiatt, Joseph, Roth, Theodore L., Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M., Frankel, Alan D., Rosenberg, Oren S., Verba, Kliment A, Agard, David A., Ott, Melanie, Emerman, Michael, Jura, Natalia, von Zastrow, Mark, Verdin, Eric, Ashworth, Alan, Schwartz, Olivier, d’Enfert, Christophe, Mukherjee, Shaeri, Jacobson, Matt, Malik, Harmit S., Fujimori, Danica G., Ideker, Trey, Craik, Charles S., Floor, Stephen N., Fraser, James S., Gross, John D., Sali, Andrej, Roth, Bryan L., Ruggero, Davide, Taunton, Jack, Kortemme, Tanja, Beltrao, Pedro, Vignuzzi, Marco, García-Sastre, Adolfo, Shokat, Kevan M., Shoichet, Brian K., Krogan, Nevan J.
Publicado 2020