A new player on the psoriasis block: IL-17A- and IL-22-producing innate lymphoid cells

por Ward, Nicole L., Umetsu, Dale T.
Publicado 2014

Cutaneous denervation of psoriasiform mouse skin improves acanthosis and inflammation in a sensory neuropeptide dependent manner

por Ostrowski, Stephen M., Belkadi, Abdelmadjid, Loyd, Candace M., Diaconu, Doina, Ward, Nicole L
Publicado 2011

Degeneration of retinal ganglion cells in diabetic dogs and mice: Relationship to glycemic control and retinal capillary degeneration

por Howell, Scott J., Mekhail, Mena N., Azem, Rami, Ward, Nicole L., Kern, Timothy S.
Publicado 2013

Botulinum neurotoxin A decreases infiltrating cutaneous lymphocytes and improves acanthosis in the KC-Tie2 mouse model

por Ward, Nicole L., Kavlick, Kevin D., Diaconu, Doina, Dawes, Sean M., Michaels, Kellie A., Gilbert, Erin
Publicado 2012

Deficiency of myeloid-related proteins 8 and 14 (Mrp8/Mrp14) does not block inflammaging but prevents steatosis

por Swindell, William R., Xing, Xianying, Fritz, Yi, Diaconu, Doina, Simon, Daniel I., Ward, Nicole L., Gudjonsson, Johann E.
Publicado 2016

RNA-seq identifies a diminished differentiation gene signature in primary monolayer keratinocytes grown from lesional and uninvolved psoriatic skin

por Swindell, William R., Sarkar, Mrinal K., Liang, Yun, Xing, Xianying, Baliwag, Jaymie, Elder, James T., Johnston, Andrew, Ward, Nicole L., Gudjonsson, Johann E.
Publicado 2017

Chronic, not acute, skin-specific inflammation promotes thrombosis in psoriasis murine models

por Golden, Jackelyn B., Wang, Yunmei, Fritz, Yi, Diaconu, Doina, Zhang, Xiufen, Debanne, Sara M., Simon, Daniel I., McCormick, Thomas S., Ward, Nicole L.
Publicado 2015

Cytokinocytes: the diverse contribution of keratinocytes to immune responses in skin

por Jiang, Yanyun, Tsoi, Lam C., Billi, Allison C., Ward, Nicole L., Harms, Paul W., Zeng, Chang, Maverakis, Emanual, Kahlenberg, J. Michelle, Gudjonsson, Johann E.
Publicado 2020

Chronic Skin-Specific Inflammation Promotes Vascular Inflammation and Thrombosis

por Wang, Yunmei, Gao, Huiyun, Loyd, Candace M., Fu, Wen, Diaconu, Doina, Liu, Shijian, Cooper, Kevin D., McCormick, Thomas S., Simon, Daniel I., Ward, Nicole L.
Publicado 2012

IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling

por Goepfert, Arnaud, Barske, Carmen, Lehmann, Sylvie, Wirth, Emmanuelle, Willemsen, Joschka, Gudjonsson, Johann E., Ward, Nicole L., Sarkar, Mrinal K., Hemmig, René, Kolbinger, Frank, Rondeau, Jean-Michel
Publicado 2022

Erlotinib-induced skin inflammation is IL-1 mediated in KC-Tie2 mice and human skin organ culture

por Ward, Nicole L., Bhagathavula, Narasimharao, Johnston, Andrew, Dawes, Sean M., Fu, Wen, Lambert, Sylviane, Dame, Michael K., Warner, Roscoe L., Gudjonsson, Johann E., Varani, James, Elder, James T.
Publicado 2014

Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis

por Swindell, William R., Michaels, Kellie A., Sutter, Andrew J., Diaconu, Doina, Fritz, Yi, Xing, Xianying, Sarkar, Mrinal K., Liang, Yun, Tsoi, Alex, Gudjonsson, Johann E., Ward, Nicole L.
Publicado 2017

RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature

por Swindell, William R., Beamer, Maria A., Sarkar, Mrinal K., Loftus, Shannon, Fullmer, Joseph, Xing, Xianying, Ward, Nicole L., Tsoi, Lam C., Kahlenberg, Michelle J., Liang, Yun, Gudjonsson, Johann E.
Publicado 2018

Evidence for biochemical barrier restoration: Topical solenopsin analogs improve inflammation and acanthosis in the KC-Tie2 mouse model of psoriasis

por Arbiser, Jack L., Nowak, Ron, Michaels, Kellie, Skabytska, Yuliya, Biedermann, Tilo, Lewis, Monica J., Bonner, Michael Y., Rao, Shikha, Gilbert, Linda C., Yusuf, Nabiha, Karlsson, Isabella, Fritz, Yi, Ward, Nicole L.
Publicado 2017

Genome-Wide Expression Profiling of Five Mouse Models Identifies Similarities and Differences with Human Psoriasis

por Swindell, William R., Johnston, Andrew, Carbajal, Steve, Han, Gangwen, Wohn, Christian, Lu, Jun, Xing, Xianying, Nair, Rajan P., Voorhees, John J., Elder, James T., Wang, Xiao-Jing, Sano, Shigetoshi, Prens, Errol P., DiGiovanni, John, Pittelkow, Mark R., Ward, Nicole L., Gudjonsson, Johann E.
Publicado 2011

Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris

por Shao, Shuai, Chen, Jiaoling, Swindell, William R., Tsoi, Lam C., Xing, Xianying, Ma, Feiyang, Uppala, Ranjitha, Sarkar, Mrinal K., Plazyo, Olesya, Billi, Allison C., Wasikowski, Rachael, Smith, Kathleen M., Honore, Prisca, Scott, Victoria E., Maverakis, Emanual, Kahlenberg, J. Michelle, Wang, Gang, Ward, Nicole L., Harms, Paul W., Gudjonsson, Johann E.
Publicado 2021

IFN-γ and TNF-α synergism may provide a link between psoriasis and inflammatory atherogenesis

por Mehta, Nehal N., Teague, Heather L., Swindell, William R., Baumer, Yvonne, Ward, Nicole L., Xing, Xianying, Baugous, Brooke, Johnston, Andrew, Joshi, Aditya A., Silverman, Joanna, Barnes, Drew H., Wolterink, Liza, Nair, Rajan P., Stuart, Philip E., Playford, Martin, Voorhees, John J., Sarkar, Mrinal K., Elder, James T., Gallagher, Katherine, Ganesh, Santhi K., Gudjonsson, Johann E.
Publicado 2017

Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis

por Ma, Feiyang, Plazyo, Olesya, Billi, Allison C., Tsoi, Lam C., Xing, Xianying, Wasikowski, Rachael, Gharaee-Kermani, Mehrnaz, Hile, Grace, Jiang, Yanyun, Harms, Paul W., Xing, Enze, Kirma, Joseph, Xi, Jingyue, Hsu, Jer-En, Sarkar, Mrinal K., Chung, Yutein, Di Domizio, Jeremy, Gilliet, Michel, Ward, Nicole L., Maverakis, Emanual, Klechevsky, Eynav, Voorhees, John J., Elder, James T., Lee, Jun Hee, Kahlenberg, J. Michelle, Pellegrini, Matteo, Modlin, Robert L., Gudjonsson, Johann E.
Publicado 2023