Metabolic and energetic benefits of microRNA-22 inhibition

por Thibonnier, Marc, Esau, Christine, Ghosh, Sujoy, Wargent, Edward, Stocker, Claire
Publicado 2020

High fat-fed GPR55 null mice display impaired glucose tolerance without concomitant changes in energy balance or insulin sensitivity but are less responsive to the effects of the c...

por Wargent, Edward T., Kepczynska, Malgorzata, Zaibi, Mohamed Sghaier, Hislop, David C., Arch, Jonathan R.S., Stocker, Claire J.
Publicado 2020

Leanness and Low Plasma Leptin in GPR17 Knockout Mice Are Dependent on Strain and Associated With Increased Energy Intake That Is Not Suppressed by Exogenous Leptin

por Wargent, Edward T., Ahmad, Suhaib J. S., Lu, Qing Richard, Kostenis, Evi, Arch, Jonathan R. S., Stocker, Claire J.
Publicado 2021

A novel method to assess collagen architecture in skin

por Osman, Osman S, Selway, Joanne L, Harikumar, Parvathy E, Stocker, Claire J, Wargent, Edward T, Cawthorne, Michael A, Jassim, Sabah, Langlands, Kenneth
Publicado 2013

Evidence from studies in rodents and in isolated adipocytes that agonists of the chemerin receptor CMKLR1 may be beneficial in the treatment of type 2 diabetes

por Wargent, Edward T., Zaibi, Mohamed S., O’Dowd, Jacqueline F., Cawthorne, Michael A., Wang, Steven J., Arch, Jonathan R.S., Stocker, Claire J.
Publicado 2015

Preventive effects of Salvia officinalis leaf extract on insulin resistance and inflammation in a model of high fat diet-induced obesity in mice that responds to rosiglitazone

por Ben Khedher, Mohamed R., Hammami, Mohamed, Arch, Jonathan R.S., Hislop, David C., Eze, Dominic, Wargent, Edward T., Kępczyńska, Małgorzata A., Zaibi, Mohamed S.
Publicado 2018

Improved Insulin Sensitivity despite Increased Visceral Adiposity in Mice Deficient for the Immune Cell Transcription Factor T-bet

por Stolarczyk, Emilie, Vong, Chi Teng, Perucha, Esperanza, Jackson, Ian, Cawthorne, Michael A., Wargent, Edward T., Powell, Nick, Canavan, James B., Lord, Graham M., Howard, Jane K.
Publicado 2013

5-HT(2A) and 5-HT(2C) receptors as hypothalamic targets of developmental programming in male rats

por Martin-Gronert, Malgorzata S., Stocker, Claire J., Wargent, Edward T., Cripps, Roselle L., Garfield, Alastair S., Jovanovic, Zorica, D'Agostino, Giuseppe, Yeo, Giles S. H., Cawthorne, Michael A., Arch, Jonathan R. S., Heisler, Lora K., Ozanne, Susan E.
Publicado 2016

Leanness in postnatally nutritionally programmed rats is associated with increased sensitivity to leptin and a melanocortin receptor agonist, and decreased sensitivity to neuropept...

por Stocker, Claire J., Wargent, Edward T., Martin-Gronert, Malgorzata S., Cripps, Roselle L., O’Dowd, Jacqueline F., Zaibi, Mohamed S., Cottrell, Elizabeth C., Mercer, Julian G., Duncan, Jacqueline S., Cawthorne, Michael A., Ozanne, Susan E., Arch, Jonathan R. S.
Publicado 2011

Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes

por Christiansen, Elisabeth, Hansen, Steffen V. F., Urban, Christian, Hudson, Brian D., Wargent, Edward T., Grundmann, Manuel, Jenkins, Laura, Zaibi, Mohamed, Stocker, Claire J., Ullrich, Susanne, Kostenis, Evi, Kassack, Matthias U., Milligan, Graeme, Cawthorne, Michael A., Ulven, Trond
Publicado 2013

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

por Yavari, Arash, Stocker, Claire J., Ghaffari, Sahar, Wargent, Edward T., Steeples, Violetta, Czibik, Gabor, Pinter, Katalin, Bellahcene, Mohamed, Woods, Angela, Martínez de Morentin, Pablo B., Cansell, Céline, Lam, Brian Y.H., Chuster, André, Petkevicius, Kasparas, Nguyen-Tu, Marie-Sophie, Martinez-Sanchez, Aida, Pullen, Timothy J., Oliver, Peter L., Stockenhuber, Alexander, Nguyen, Chinh, Lazdam, Merzaka, O’Dowd, Jacqueline F., Harikumar, Parvathy, Tóth, Mónika, Beall, Craig, Kyriakou, Theodosios, Parnis, Julia, Sarma, Dhruv, Katritsis, George, Wortmann, Diana D.J., Harper, Andrew R., Brown, Laurence A., Willows, Robin, Gandra, Silvia, Poncio, Victor, de Oliveira Figueiredo, Márcio J., Qi, Nathan R., Peirson, Stuart N., McCrimmon, Rory J., Gereben, Balázs, Tretter, László, Fekete, Csaba, Redwood, Charles, Yeo, Giles S.H., Heisler, Lora K., Rutter, Guy A., Smith, Mark A., Withers, Dominic J., Carling, David, Sternick, Eduardo B., Arch, Jonathan R.S., Cawthorne, Michael A., Watkins, Hugh, Ashrafian, Houman
Publicado 2016