Pi sampling: a methodical and flexible approach to initial macromolecular crystallization screening

por Gorrec, Fabrice, Palmer, Colin M., Lebon, Guillaume, Warne, Tony
Publicado 2011

Crystal Structures of a Stabilized β(1)-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol

por Warne, Tony, Edwards, Patricia C., Leslie, Andrew G.W., Tate, Christopher G.
Publicado 2012

Structure of the adenosine A(2A) receptor bound to an engineered G protein

por Carpenter, Byron, Nehmé, Rony, Warne, Tony, Leslie, Andrew G. W., Tate, Christopher G.
Publicado 2016

Insight into partial agonism by observing multiple equilibria for ligand-bound and G(s)-mimetic nanobody-bound β(1)-adrenergic receptor

por Solt, Andras S., Bostock, Mark J., Shrestha, Binesh, Kumar, Prashant, Warne, Tony, Tate, Christopher G., Nietlispach, Daniel
Publicado 2017

Agonist-bound adenosine A(2A) receptor structures reveal common features of GPCR activation

por Lebon, Guillaume, Warne, Tony, Edwards, Patricia C., Bennett, Kirstie, Langmead, Christopher J., Leslie, Andrew G.W., Tate, Christopher G.
Publicado 2011

The 2.1 Å Resolution Structure of Cyanopindolol-Bound β(1)-Adrenoceptor Identifies an Intramembrane Na(+) Ion that Stabilises the Ligand-Free Receptor

por Miller-Gallacher, Jennifer L., Nehmé, Rony, Warne, Tony, Edwards, Patricia C., Schertler, Gebhard F. X., Leslie, Andrew G. W., Tate, Christopher G.
Publicado 2014

Complete Reversible Refolding of a G-Protein Coupled Receptor on a Solid Support

por Di Bartolo, Natalie, Compton, Emma L. R., Warne, Tony, Edwards, Patricia C., Tate, Christopher G., Schertler, Gebhard F. X., Booth, Paula J.
Publicado 2016

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

por Warne, Tony, Moukhametzianov, Rouslan, Baker, Jillian G., Nehmé, Rony, Edwards, Patricia C., Leslie, Andrew G.W., Schertler, Gebhard F.X., Tate, Christopher G.
Publicado 2011

Biophysical Fragment Screening of the β(1)-Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design

por Christopher, John A., Brown, Jason, Doré, Andrew S., Errey, James C., Koglin, Markus, Marshall, Fiona H., Myszka, David G., Rich, Rebecca L., Tate, Christopher G., Tehan, Benjamin, Warne, Tony, Congreve, Miles
Publicado 2013

PIP(2) stabilises active states of GPCRs and enhances the selectivity of G-protein coupling

por Yen, Hsin-Yung, Hoi, Kin Kuan, Liko, Idlir, Hedger, George, Horrell, Michael R., Song, Wanling, Wu, Di, Heine, Philipp, Warne, Tony, Lee, Yang, Carpenter, Byron, Plückthun, Andreas, Tate, Christopher G., Sansom, Mark S. P., Robinson, Carol V.
Publicado 2018