Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants

por Fung, Kenneth, Ramírez, Julia, Warren, Helen R., Aung, Nay, Lee, Aaron M., Tzanis, Evan, Petersen, Steffen E., Munroe, Patricia B.
Publicado 2019

Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system

por Ramírez, Julia, Duijvenboden, Stefan van, Ntalla, Ioanna, Mifsud, Borbala, Warren, Helen R, Tzanis, Evan, Orini, Michele, Tinker, Andrew, Lambiase, Pier D., Munroe, Patricia B.
Publicado 2018

Genetically Determined Serum Calcium Levels and Markers of Ventricular Repolarization: A Mendelian Randomization Study in the UK Biobank

por Young, William J., Warren, Helen R., Mook-Kanamori, Dennis O., Ramírez, Julia, van Duijvenboden, Stefan, Orini, Michele, Tinker, Andrew, van Heemst, Diana, Lambiase, Pier D., Jukema, J. Wouter, Munroe, Patricia B., Noordam, Raymond
Publicado 2021

Hypertension and the roles of the 9p21.3 risk locus: Classic findings and new association data

por Gallo, Juan E., Ochoa, Juan E., Warren, Helen R., Misas, Elizabeth, Correa, Monica M., Gallo-Villegas, Jaime A., Bedoya, Gabriel, Aristizábal, Dagnóvar, McEwen, Juan G., Caulfield, Mark J., Parati, Gianfranco, Clay, Oliver K.
Publicado 2020

Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos

por Sofer, Tamar, Wong, Quenna, Hartwig, Fernando P., Taylor, Kent, Warren, Helen R., Evangelou, Evangelos, Cabrera, Claudia P., Levy, Daniel, Kramer, Holly, Lange, Leslie A., Horta, Bernardo L., Kerr, Kathleen F., Reiner, Alex P., Franceschini, Nora
Publicado 2017

The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle

por Ren, Meixia, Ng, Fu Liang, Warren, Helen R, Witkowska, Kate, Baron, Michael, Jia, Zhilong, Cabrera, Claudia, Zhang, Ruoxin, Mifsud, Borbala, Munroe, Patricia B, Xiao, Qingzhong, Townsend-Nicholson, Andrea, Hobbs, Adrian J, Ye, Shu, Caulfield, Mark J
Publicado 2018

Phospholemman Phosphorylation Regulates Vascular Tone, Blood Pressure, and Hypertension in Mice and Humans

por Boguslavskyi, Andrii, Tokar, Sergiy, Prysyazhna, Oleksandra, Rudyk, Olena, Sanchez-Tatay, David, Lemmey, Hamish A.L., Dora, Kim A., Garland, Christopher J., Warren, Helen R., Doney, Alexander, Palmer, Colin N.A., Caulfield, Mark J., Vlachaki Walker, Julia, Howie, Jacqueline, Fuller, William, Shattock, Michael J.
Publicado 2020

Heteroplasmic mitochondrial DNA variants in cardiovascular diseases

por Calabrese, Claudia, Pyle, Angela, Griffin, Helen, Coxhead, Jonathan, Hussain, Rafiqul, Braund, Peter S, Li, Linxin, Burgess, Annette, Munroe, Patricia B, Little, Louis, Warren, Helen R, Cabrera, Claudia, Hall, Alistair, Caulfield, Mark J, Rothwell, Peter M, Samani, Nilesh J, Hudson, Gavin, Chinnery, Patrick F.
Publicado 2022

Genome-Wide Analysis of Left Ventricular Image-Derived Phenotypes Identifies Fourteen Loci Associated With Cardiac Morphogenesis and Heart Failure Development

por Aung, Nay, Vargas, Jose D., Yang, Chaojie, Cabrera, Claudia P., Warren, Helen R., Fung, Kenneth, Tzanis, Evan, Barnes, Michael R., Rotter, Jerome I., Taylor, Kent D., Manichaikul, Ani W., Lima, Joao A.C., Bluemke, David A., Piechnik, Stefan K., Neubauer, Stefan, Munroe, Patricia B., Petersen, Steffen E.
Publicado 2019

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

por Trompet, Stella, Postmus, Iris, Warren, Helen R., Noordam, Raymond, Smit, Roelof A. J., Theusch, Elizabeth, Li, Xiaohui, Arsenault, Benoit, Chasman, Daniel I., Hitman, Graham A., Munroe, Patricia B., Rotter, Jerome I., Psaty, Bruce M., Caulfield, Mark J., Krauss, Ron M., Cupples, Adrienne L., Jukema, Wouter J.
Publicado 2022

Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease

por Marouli, Eirini, Del Greco, M. Fabiola, Astley, Christina M., Yang, Jian, Ahmad, Shafqat, Berndt, Sonja I., Caulfield, Mark J., Evangelou, Evangelos, McKnight, Barbara, Medina-Gomez, Carolina, van Vliet-Ostaptchouk, Jana V., Warren, Helen R., Zhu, Zhihong, Hirschhorn, Joel N., Loos, Ruth J. F., Kutalik, Zoltan, Deloukas, Panos
Publicado 2019

IGSF10 mutations dysregulate gonadotropin‐releasing hormone neuronal migration resulting in delayed puberty

por Howard, Sasha R, Guasti, Leonardo, Ruiz‐Babot, Gerard, Mancini, Alessandra, David, Alessia, Storr, Helen L, Metherell, Lousie A, Sternberg, Michael JE, Cabrera, Claudia P, Warren, Helen R, Barnes, Michael R, Quinton, Richard, de Roux, Nicolas, Young, Jacques, Guiochon‐Mantel, Anne, Wehkalampi, Karoliina, André, Valentina, Gothilf, Yoav, Cariboni, Anna, Dunkel, Leo
Publicado 2016

Genome‐Wide Meta‐Analysis of Blood Pressure Response to β(1)‐Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)

por Singh, Sonal, Warren, Helen R., Hiltunen, Timo P., McDonough, Caitrin W., El Rouby, Nihal, Salvi, Erika, Wang, Zhiying, Garofalidou, Tatiana, Fyhrquist, Frej, Kontula, Kimmo K., Glorioso, Valeria, Zaninello, Roberta, Glorioso, Nicola, Pepine, Carl J., Munroe, Patricia B., Turner, Stephan T., Chapman, Arlene B., Boerwinkle, Eric, Johnson, Julie A., Gong, Yan, Cooper‐DeHoff, Rhonda M.
Publicado 2019

KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern

por Teumer, Alexander, Trenkwalder, Teresa, Kessler, Thorsten, Jamshidi, Yalda, van den Berg, Marten E., Kaess, Bernhard, Nelson, Christopher P., Bastiaenen, Rachel, De Bortoli, Marzia, Rossini, Alessandra, Deisenhofer, Isabel, Stark, Klaus, Assa, Solmaz, Braund, Peter S., Cabrera, Claudia, Dominiczak, Anna F., Gögele, Martin, Hall, Leanne M., Ikram, M. Arfan, Kavousi, Maryam, Lackner, Karl J., Müller, Christian, Münzel, Thomas, Nauck, Matthias, Padmanabhan, Sandosh, Pfeiffer, Norbert, Spector, Tim D., Uitterlinden, Andre G., Verweij, Niek, Völker, Uwe, Warren, Helen R., Zafar, Mobeen, Felix, Stephan B., Kors, Jan A., Snieder, Harold, Munroe, Patricia B., Pattaro, Cristian, Fuchsberger, Christian, Schmidt, Georg, Nolte, Ilja M., Schunkert, Heribert, Pramstaller, Peter P., Wild, Philipp S., van der Harst, Pim, Stricker, Bruno H., Schnabel, Renate B., Samani, Nilesh J., Hengstenberg, Christian, Dörr, Marcus, Behr, Elijah R., Reinhard, Wibke
Publicado 2019

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

por Warren, Helen R, Evangelou, Evangelos, Cabrera, Claudia P, Gao, He, Ren, Meixia, Mifsud, Borbala, Ntalla, Ioanna, Surendran, Praveen, Liu, Chunyu, Cook, James P, Kraja, Aldi T, Drenos, Fotios, Loh, Marie, Verweij, Niek, Marten, Jonathan, Karaman, Ibrahim, Segura Lepe, Marcelo P, O’Reilly, Paul F, Knight, Joanne, Snieder, Harold, Kato, Norihiro, He, Jiang, Tai, E Shyong, Said, M Abdullah, Porteous, David, Alver, Maris, Poulter, Neil, Farrall, Martin, Gansevoort, Ron T, Padmanabhan, Sandosh, Mägi, Reedik, Stanton, Alice, Connell, John, Bakker, Stephan J L, Metspalu, Andres, Shields, Denis C, Thom, Simon, Brown, Morris, Sever, Peter, Esko, Tõnu, Hayward, Caroline, van der Harst, Pim, Saleheen, Danish, Chowdhury, Rajiv, Chambers, John C, Chasman, Daniel I, Chakravarti, Aravinda, Newton-Cheh, Christopher, Lindgren, Cecilia M, Levy, Daniel, Kooner, Jaspal S, Keavney, Bernard, Tomaszewski, Maciej, Samani, Nilesh J, Howson, Joanna M M, Tobin, Martin D, Munroe, Patricia B, Ehret, Georg B, Wain, Louise V, Barnes, Michael R, Tzoulaki, Ioanna, Caulfield, Mark J, Elliott, Paul
Publicado 2017

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

por van Setten, Jessica, Verweij, Niek, Mbarek, Hamdi, Niemeijer, Maartje N., Trompet, Stella, Arking, Dan E., Brody, Jennifer A., Gandin, Ilaria, Grarup, Niels, Hall, Leanne M., Hemerich, Daiane, Lyytikäinen, Leo-Pekka, Mei, Hao, Müller-Nurasyid, Martina, Prins, Bram P., Robino, Antonietta, Smith, Albert V., Warren, Helen R., Asselbergs, Folkert W., Boomsma, Dorret I., Caulfield, Mark J., Eijgelsheim, Mark, Ford, Ian, Hansen, Torben, Harris, Tamara B., Heckbert, Susan R., Hottenga, Jouke-Jan, Iorio, Annamaria, Kors, Jan A., Linneberg, Allan, MacFarlane, Peter W., Meitinger, Thomas, Nelson, Christopher P., Raitakari, Olli T., Silva Aldana, Claudia T., Sinagra, Gianfranco, Sinner, Moritz, Soliman, Elsayed Z., Stoll, Monika, Uitterlinden, Andre, van Duijn, Cornelia M., Waldenberger, Melanie, Alonso, Alvaro, Gasparini, Paolo, Gudnason, Vilmundur, Jamshidi, Yalda, Kääb, Stefan, Kanters, Jørgen K., Lehtimäki, Terho, Munroe, Patricia B., Peters, Annette, Samani, Nilesh J., Sotoodehnia, Nona, Ulivi, Sheila, Wilson, James G., de Geus, Eco J. C., Jukema, J. Wouter, Stricker, Bruno, van der Harst, Pim, de Bakker, Paul I. W., Isaacs, Aaron
Publicado 2019

Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease

por Young, William J., Haessler, Jeffrey, Benjamins, Jan-Walter, Repetto, Linda, Yao, Jie, Isaacs, Aaron, Harper, Andrew R., Ramirez, Julia, Garnier, Sophie, van Duijvenboden, Stefan, Baldassari, Antoine R., Concas, Maria Pina, Duong, ThuyVy, Foco, Luisa, Isaksen, Jonas L., Mei, Hao, Noordam, Raymond, Nursyifa, Casia, Richmond, Anne, Santolalla, Meddly L., Sitlani, Colleen M., Soroush, Negin, Thériault, Sébastien, Trompet, Stella, Aeschbacher, Stefanie, Ahmadizar, Fariba, Alonso, Alvaro, Brody, Jennifer A., Campbell, Archie, Correa, Adolfo, Darbar, Dawood, De Luca, Antonio, Deleuze, Jean-François, Ellervik, Christina, Fuchsberger, Christian, Goel, Anuj, Grace, Christopher, Guo, Xiuqing, Hansen, Torben, Heckbert, Susan R., Jackson, Rebecca D., Kors, Jan A., Lima-Costa, Maria Fernanda, Linneberg, Allan, Macfarlane, Peter W., Morrison, Alanna C., Navarro, Pau, Porteous, David J., Pramstaller, Peter P., Reiner, Alexander P., Risch, Lorenz, Schotten, Ulrich, Shen, Xia, Sinagra, Gianfranco, Soliman, Elsayed Z., Stoll, Monika, Tarazona-Santos, Eduardo, Tinker, Andrew, Trajanoska, Katerina, Villard, Eric, Warren, Helen R., Whitsel, Eric A., Wiggins, Kerri L., Arking, Dan E., Avery, Christy L., Conen, David, Girotto, Giorgia, Grarup, Niels, Hayward, Caroline, Jukema, J.Wouter, Mook-Kanamori, Dennis O., Olesen, Morten Salling, Padmanabhan, Sandosh, Psaty, Bruce M., Pattaro, Cristian, Ribeiro, Antonio Luiz P., Rotter, Jerome I., Stricker, Bruno H., van der Harst, Pim, van Duijn, Cornelia M., Verweij, Niek, Wilson, James G., Orini, Michele, Charron, Philippe, Watkins, Hugh, Kooperberg, Charles, Lin, Henry J., Wilson, James F., Kanters, Jørgen K., Sotoodehnia, Nona, Mifsud, Borbala, Lambiase, Pier D., Tereshchenko, Larisa G., Munroe, Patricia B.
Publicado 2023

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

por Bihlmeyer, Nathan A., Brody, Jennifer A., Smith, Albert Vernon, Warren, Helen R., Lin, Honghuang, Isaacs, Aaron, Liu, Ching-Ti, Marten, Jonathan, Radmanesh, Farid, Hall, Leanne M., Grarup, Niels, Mei, Hao, Müller-Nurasyid, Martina, Huffman, Jennifer E., Verweij, Niek, Guo, Xiuqing, Yao, Jie, Li-Gao, Ruifang, van den Berg, Marten, Weiss, Stefan, Prins, Bram P., van Setten, Jessica, Haessler, Jeffrey, Lyytikäinen, Leo-Pekka, Li, Man, Alonso, Alvaro, Soliman, Elsayed Z., Bis, Joshua C., Austin, Tom, Chen, Yii-Der Ida, Psaty, Bruce M., Harrris, Tamara B., Launer, Lenore J., Padmanabhan, Sandosh, Dominiczak, Anna, Huang, Paul L., Xie, Zhijun, Ellinor, Patrick T., Kors, Jan A., Campbell, Archie, Murray, Alison D., Nelson, Christopher P., Tobin, Martin D., Bork-Jensen, Jette, Hansen, Torben, Pedersen, Oluf, Linneberg, Allan, Sinner, Moritz F., Peters, Annette, Waldenberger, Melanie, Meitinger, Thomas, Perz, Siegfried, Kolcic, Ivana, Rudan, Igor, de Boer, Rudolf A., van der Meer, Peter, Lin, Henry J., Taylor, Kent D., de Mutsert, Renée, Trompet, Stella, Jukema, J. Wouter, Maan, Arie C., Stricker, Bruno H.C., Rivadeneira, Fernando, Uitterlinden, André, Völker, Uwe, Homuth, Georg, Völzke, Henry, Felix, Stephan B., Mangino, Massimo, Spector, Timothy D., Bots, Michiel L., Perez, Marco, Raitakari, Olli T., Kähönen, Mika, Mononen, Nina, Gudnason, Vilmundur, Munroe, Patricia B., Lubitz, Steven A., van Duijn, Cornelia M., Newton-Cheh, Christopher H., Hayward, Caroline, Rosand, Jonathan, Samani, Nilesh J., Kanters, Jørgen K., Wilson, James G., Kääb, Stefan, Polasek, Ozren, van der Harst, Pim, Heckbert, Susan R., Rotter, Jerome I., Mook-Kanamori, Dennis O., Eijgelsheim, Mark, Dörr, Marcus, Jamshidi, Yalda, Asselbergs, Folkert W., Kooperberg, Charles, Lehtimäki, Terho, Arking, Dan E., Sotoodehnia, Nona
Publicado 2018

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

por Giri, Ayush, Hellwege, Jacklyn N., Keaton, Jacob M., Park, Jihwan, Qiu, Chengxiang, Warren, Helen R., Torstenson, Eric S., Kovesdy, Csaba P., Sun, Yan V., Wilson, Otis D., Robinson-Cohen, Cassianne, Roumie, Christianne L., Chung, Cecilia P., Birdwell, Kelly A., Damrauer, Scott M., DuVall, Scott L., Klarin, Derek, Cho, Kelly, Wang, Yu, Evangelou, Evangelos, Cabrera, Claudia P., Wain, Louise V., Shrestha, Rojesh, Mautz, Brian S., Akwo, Elvis A., Sargurupremraj, Muralidharan, Debette, Stéphanie, Boehnke, Michael, Scott, Laura J., Luan, Jian’an, Jing-Hua, Zhao, Willems, Sara M., Thériault, Sébastien, Shah, Nabi, Oldmeadow, Christopher, Almgren, Peter, Li-Gao, Ruifang, Verweij, Niek, Boutin, Thibaud S., Mangino, Massimo, Ntalla, Ioanna, Feofanova, Elena, Surendran, Praveen, Cook, James P., Karthikeyan, Savita, Lahrouchi, Najim, Liu, Chunyu, Sepúlveda, Nuno, Richardson, Tom G., Kraja, Aldi, Amouyel, Philippe, Farrall, Martin, Poulter, Neil R., Laakso, Markku, Zeggini, Eleftheria, Sever, Peter, Scott, Robert A., Langenberg, Claudia, Wareham, Nicholas J., Conen, David, Alexander Palmer, Colin Neil, Attia, John, Chasman, Daniel I., Ridker, Paul M., Melander, Olle, Mook-Kanamori, Dennis Owen, van der Harst, Pim, Cucca, Francesco, Schlessinger, David, Hayward, Caroline, Spector, Tim D., Marjo-Riitta, Jarvelin, Hennig, Branwen J., Timpson, Nicholas J., Wei-Qi, Wei, Smith, Joshua C., Xu, Yaomin, Matheny, Michael E., Siew, Edward E., Lindgren, Cecilia, Karl-Heinz, Herzig, Dedoussis, George, Denny, Joshua C., Psaty, Bruce M., Howson, Joanna M. M., Munroe, Patricia B., Newton-Cheh, Christopher, Caulfield, Mark J., Elliott, Paul, Gaziano, J. Michael, Concato, John, Wilson, Peter W.F., Tsao, Philip S., Velez Edwards, Digna R., Susztak, Katalin, O’Donnell, Christopher J., Hung, Adriana M., Edwards, Todd L.
Publicado 2018

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

por Postmus, Iris, Trompet, Stella, Deshmukh, Harshal A., Barnes, Michael R., Li, Xiaohui, Warren, Helen R., Chasman, Daniel I., Zhou, Kaixin, Arsenault, Benoit J., Donnelly, Louise A., Wiggins, Kerri L., Avery, Christy L., Griffin, Paula, Feng, QiPing, Taylor, Kent D., Li, Guo, Evans, Daniel S., Smith, Albert V., de Keyser, Catherine E., Johnson, Andrew D., de Craen, Anton J. M., Stott, David J., Buckley, Brendan M., Ford, Ian, Westendorp, Rudi G. J., Eline Slagboom, P., Sattar, Naveed, Munroe, Patricia B., Sever, Peter, Poulter, Neil, Stanton, Alice, Shields, Denis C., O’Brien, Eoin, Shaw-Hawkins, Sue, Ida Chen, Y.-D., Nickerson, Deborah A., Smith, Joshua D., Pierre Dubé, Marie, Matthijs Boekholdt, S., Kees Hovingh, G., Kastelein, John J. P., McKeigue, Paul M., Betteridge, John, Neil, Andrew, Durrington, Paul N., Doney, Alex, Carr, Fiona, Morris, Andrew, McCarthy, Mark I., Groop, Leif, Ahlqvist, Emma, Bis, Joshua C., Rice, Kenneth, Smith, Nicholas L., Lumley, Thomas, Whitsel, Eric A., Stürmer, Til, Boerwinkle, Eric, Ngwa, Julius S., O’Donnell, Christopher J., Vasan, Ramachandran S., Wei, Wei-Qi, Wilke, Russell A., Liu, Ching-Ti, Sun, Fangui, Guo, Xiuqing, Heckbert, Susan R, Post, Wendy, Sotoodehnia, Nona, Arnold, Alice M., Stafford, Jeanette M., Ding, Jingzhong, Herrington, David M., Kritchevsky, Stephen B., Eiriksdottir, Gudny, Launer, Leonore J., Harris, Tamara B., Chu, Audrey Y., Giulianini, Franco, MacFadyen, Jean G., Barratt, Bryan J., Nyberg, Fredrik, Stricker, Bruno H., Uitterlinden, André G., Hofman, Albert, Rivadeneira, Fernando, Emilsson, Valur, Franco, Oscar H., Ridker, Paul M., Gudnason, Vilmundur, Liu, Yongmei, Denny, Joshua C., Ballantyne, Christie M., Rotter, Jerome I., Adrienne Cupples, L., Psaty, Bruce M., Palmer, Colin N. A., Tardif, Jean-Claude, Colhoun, Helen M., Hitman, Graham, Krauss, Ronald M., Wouter Jukema, J, Caulfield, Mark J.
Publicado 2014