Neutrophil Elastase-mediated proteolysis activates the anti-inflammatory cytokine IL-36 Receptor antagonist

por Macleod, Tom, Doble, Rosella, McGonagle, Dennis, Wasson, Christopher W., Alase, Adewonuola, Stacey, Martin, Wittmann, Miriam
Publicado 2016

Alkyl-imino sugars inhibit the pro-oncogenic ion channel function of human papillomavirus (HPV) E5

por Wetherill, Laura F., Wasson, Christopher W., Swinscoe, Gemma, Kealy, David, Foster, Richard, Griffin, Stephen, Macdonald, Andrew
Publicado 2018

The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes

por Richards, Kathryn H., Wasson, Christopher W., Watherston, Oliver, Doble, Rosella, Eric Blair, G., Wittmann, Miriam, Macdonald, Andrew
Publicado 2015

Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus lif...

por Wasson, Christopher W., Morgan, Ethan L., Müller, Marietta, Ross, Rebecca L., Hartley, Margaret, Roberts, Sally, Macdonald, Andrew
Publicado 2017

Inhibition of Plk1 and Cyclin B1 Expression Results in Panobinostat-Induced G(2) Delay and Mitotic Defects

por Prystowsky, Michael, Feeney, Katherine, Kawachi, Nicole, Montagna, Cristina, Willmott, Michelle, Wasson, Christopher, Antkowiak, Maciej, Loudig, Olivier, Parish, Joanna
Publicado 2013

E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer

por Morgan, Ethan L., Scarth, James A., Patterson, Molly R., Wasson, Christopher W., Hemingway, Georgia C., Barba-Moreno, Diego, Macdonald, Andrew
Publicado 2020

YIP1 family member 4 (YIPF4) is a novel cellular binding partner of the papillomavirus E5 proteins

por Müller, Marietta, Wasson, Christopher W., Bhatia, Ramya, Boxall, Sally, Millan, David, Goh, Grace Y.S., Haas, Jürgen, Stonehouse, Nicola J., Macdonald, Andrew
Publicado 2015

Glibenclamide inhibits BK polyomavirus infection in kidney cells through CFTR blockade

por Panou, Margarita-Maria, Antoni, Michelle, Morgan, Ethan L., Loundras, Eleni-Anna, Wasson, Christopher W., Welberry-Smith, Matthew, Mankouri, Jamel, Macdonald, Andrew
Publicado 2020

Long non-coding RNA HOTAIR induces GLI2 expression through Notch signalling in systemic sclerosis dermal fibroblasts

por Wasson, Christopher W., Ross, Rebecca L., Wells, Rebecca, Corinaldesi, Clarissa, Georgiou, Ioanna Ch., Riobo-Del Galdo, Natalia A., Del Galdo, Francesco
Publicado 2020

Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH

por Wasson, Christopher W, Abignano, Giuseppina, Hermes, Heidi, Malaab, Maya, Ross, Rebecca L, Jimenez, Sergio A, Chang, Howard Y, Feghali-Bostwick, Carol A, del Galdo, Francesco
Publicado 2020

Induction of Pro-Fibrotic CLIC4 in Dermal Fibroblasts by TGF-β/Wnt3a Is Mediated by GLI2 Upregulation

por Wasson, Christopher W., Caballero-Ruiz, Begoña, Gillespie, Justin, Derrett-Smith, Emma, Mankouri, Jamel, Denton, Christopher P., Canettieri, Gianluca, Riobo-Del Galdo, Natalia A., Del Galdo, Francesco
Publicado 2022

Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation

por Stakaitytė, Gabrielė, Nwogu, Nnenna, Dobson, Samuel J., Knight, Laura M., Wasson, Christopher W., Salguero, Francisco J., Blackbourn, David J., Blair, G. Eric, Mankouri, Jamel, Macdonald, Andrew, Whitehouse, Adrian
Publicado 2018

Exploitation of ATP-sensitive potassium ion (K(ATP)) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling

por Scarth, James A., Wasson, Christopher W., Patterson, Molly R., Evans, Debra, Barba-Moreno, Diego, Carden, Holli, Cassidy, Rosa, Whitehouse, Adrian, Mankouri, Jamel, Samson, Adel, Morgan, Ethan L., Macdonald, Andrew
Publicado 2023

MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer

por Morgan, Ethan L., Patterson, Molly R., Ryder, Emma L., Lee, Siu Yi, Wasson, Christopher W., Harper, Katherine L., Li, Yigen, Griffin, Stephen, Blair, G. Eric, Whitehouse, Adrian, Macdonald, Andrew
Publicado 2020

STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle

por Morgan, Ethan L., Wasson, Christopher W., Hanson, Lucy, Kealy, David, Pentland, Ieisha, McGuire, Victoria, Scarpini, Cinzia, Coleman, Nicholas, Arthur, J. Simon C., Parish, Joanna L., Roberts, Sally, Macdonald, Andrew
Publicado 2018

Targeting human plasmacytoid dendritic cells through BDCA2 prevents skin inflammation and fibrosis in a novel xenotransplant mouse model of scleroderma

por Ross, Rebecca L, Corinaldesi, Clarissa, Migneco, Gemma, Carr, Ian M, Antanaviciute, Agne, Wasson, Christopher W, Carriero, Antonio, Distler, Jörg H W, Holmes, Steve, El-Sherbiny, Yasser M, McKimmie, Clive S, Del Galdo, Francesco
Publicado 2021