Menahydroquinone-4 Prodrug: A Promising Candidate Anti-Hepatocellular Carcinoma Agent

por Enjoji, Munechika, Watase, Daisuke, Matsunaga, Kazuhisa, Kusuda, Mariko, Nagata-Akaho, Nami, Karube, Yoshiharu, Takata, Jiro
Publicado 2015

Prodrugs for Skin Delivery of Menahydroquinone-4, an Active Form of Vitamin K(2(20)), Could Overcome the Photoinstability and Phototoxicity of Vitamin K(2(20))

por Goto, Shotaro, Setoguchi, Shuichi, Yamakawa, Hirofumi, Watase, Daisuke, Terada, Kazuki, Matsunaga, Kazuhisa, Karube, Yoshiharu, Takata, Jiro
Publicado 2019

Novel Cationic Prodrug of Ubiquinol-10 Enhances Intestinal Absorption via Efficient Formation of Nanosized Mixed-Micelles with Bile Acid Anions

por Setoguchi, Shuichi, Hidaka, Ryoji, Nagata-Akaho, Nami, Watase, Daisuke, Koga, Mitsuhisa, Matsunaga, Kazuhisa, Karube, Yoshiharu, Takata, Jiro
Publicado 2020

Antitumor Effects and Delivery Profiles of Menahydroquinone-4 Prodrugs with Ionic or Nonionic Promoiety to Hepatocellular Carcinoma Cells

por Setoguchi, Shuichi, Watase, Daisuke, Matsunaga, Kazuhisa, Yamakawa, Hirofumi, Goto, Shotaro, Terada, Kazuki, Ohe, Kenji, Enjoji, Munechika, Karube, Yoshiharu, Takata, Jiro
Publicado 2018

Cationic N,N-Dimethylglycine Ester Prodrug of 2R-α-Tocotrienol Promotes Intestinal Absorption via Efficient Self-Micellization with Intrinsic Bile Acid Anion

por Watase, Daisuke, Setoguchi, Shuichi, Nagata-Akaho, Nami, Goto, Shotaro, Yamakawa, Hirofumi, Yamada, Ayano, Koga, Mitsuhisa, Karube, Yoshiharu, Matsunaga, Kazuhisa, Takata, Jiro
Publicado 2022

Atypical Antipsychotic Drug Ziprasidone Protects against Rotenone-Induced Neurotoxicity: An In Vitro Study

por Terada, Kazuki, Murata, Ayumi, Toki, Erina, Goto, Shotaro, Yamakawa, Hirofumi, Setoguchi, Shuichi, Watase, Daisuke, Koga, Mitsuhisa, Takata, Jiro, Matsunaga, Kazuhisa, Karube, Yoshiharu
Publicado 2020

Growth Inhibitory Effects of Ester Derivatives of Menahydroquinone-4, the Reduced Form of Vitamin K(2(20)), on All-Trans Retinoic Acid-Resistant HL60 Cell Line

por Yamakawa, Hirofumi, Setoguchi, Shuichi, Goto, Shotaro, Watase, Daisuke, Terada, Kazuki, Nagata-Akaho, Nami, Toki, Erina, Koga, Mitsuhisa, Matsunaga, Kazuhisa, Karube, Yoshiharu, Takata, Jiro
Publicado 2021

Delivery of the reduced form of vitamin K(2(20)) to NIH/3T3 cells partially protects against rotenone induced cell death

por Toki, Erina, Goto, Shotaro, Setoguchi, Shuichi, Terada, Kazuki, Watase, Daisuke, Yamakawa, Hirofumi, Yamada, Ayano, Koga, Mitsuhisa, Kubota, Kaori, Iwasaki, Katsunori, Karube, Yoshiharu, Matsunaga, Kazuhisa, Takata, Jiro
Publicado 2022