Impact of Molecular Genetics on Clinical Cardiology

por Mayosi, Bongani M, Watkins, Hugh
Publicado 1999

Localisation of AMPK γ subunits in cardiac and skeletal muscles

por Pinter, Katalin, Grignani, Robert T., Watkins, Hugh, Redwood, Charles
Publicado 2013

Manhattan++: displaying genome-wide association summary statistics with multiple annotation layers

por Grace, Christopher, Farrall, Martin, Watkins, Hugh, Goel, Anuj
Publicado 2019

Determination of AMP-activated protein kinase phosphorylation sites in recombinant protein expressed using the pET28a vector: A cautionary tale

por Renz, Bernhard, Davies, Joanna K., Carling, David, Watkins, Hugh, Redwood, Charles
Publicado 2009

Stakeholder views on secondary findings in whole-genome and whole-exome sequencing: a systematic review of quantitative and qualitative studies

por Mackley, Michael P., Fletcher, Benjamin, Parker, Michael, Watkins, Hugh, Ormondroyd, Elizabeth
Publicado 2017

Robust estimates of heritable coronary disease risk in individuals with type 2 diabetes

por Grace, Christopher, Hopewell, Jemma C., Watkins, Hugh, Farrall, Martin, Goel, Anuj
Publicado 2021

Embryonic expression of AMPK γ subunits and the identification of a novel γ2 transcript variant in adult heart

por Pinter, Katalin, Grignani, Robert T., Czibik, Gabor, Farza, Hend, Watkins, Hugh, Redwood, Charles
Publicado 2012

Mavacamten rescues increased myofilament calcium sensitivity and dysregulation of Ca(2+) flux caused by thin filament hypertrophic cardiomyopathy mutations

por Sparrow, Alexander J., Watkins, Hugh, Daniels, Matthew J., Redwood, Charles, Robinson, Paul
Publicado 2020

Lack of genetic support for shared aetiology of Coronary Artery Disease and Late-onset Alzheimer’s disease

por Grace, Christopher, Clarke, Robert, Goel, Anuj, Farrall, Martin, Watkins, Hugh, Hopewell, Jemma C.
Publicado 2018

Views of rare disease participants in a UK whole-genome sequencing study towards secondary findings: a qualitative study

por Mackley, Michael P, Blair, Edward, Parker, Michael, Taylor, Jenny C, Watkins, Hugh, Ormondroyd, Elizabeth
Publicado 2018

Patients with hypertrophic cardiomyopathy (HCM) and HCM gene carriers have attenuated myocardial oxygenation response to vasodilator stress - a potential mechanism for sudden cardi...

por Dass, Sairia, Karamitsos, Theodoros, Suttie, Joseph, Sever, Emily, Jerosch-Herold, Michael, Watkins, Hugh, Neubauer, Stefan
Publicado 2012

In vivo mouse cardiac hyperpolarized magnetic resonance spectroscopy

por Dodd, Michael S, Ball, Vicky, Bray, Rosalind, Ashrafian, Houman, Watkins, Hugh, Clarke, Kieran, Tyler, Damian J
Publicado 2013

Relationship between CMR and ECG-derived indices of left ventricular hypertrophy

por Nethononda, Richard M, Casadei, Barbara, Whitworth, Polly, Francis, Jane, Alder, Nicola, Watkins, Hugh, Neubauer, Stefan
Publicado 2009

Patients with Dilated Cardiomyopathy (DCM) have appropriate myocardial oxygenation response to vasodilator stress

por Dass, Sairia, Holloway, Cameron, Suttie, Joseph, Mahmod, Masliza, Sever, Emily, Watkins, Hugh, Neubauer, Stefan, Karamitsos, Theodoros
Publicado 2013

Inherited aortopathy assessment in bicuspid aortic valve disease relative

por Bissell, Malenka M, Biasiolli, Luca, Oswal, Abhishek, Loudon, Margaret, Watkins, Hugh, Neubauer, Stefan, Myerson, Saul G
Publicado 2016

Do health professionals value genomic testing? A discrete choice experiment in inherited cardiovascular disease

por Buchanan, James, Blair, Edward, Thomson, Kate L., Ormondroyd, Elizabeth, Watkins, Hugh, Taylor, Jenny C., Wordsworth, Sarah
Publicado 2019

Data-driven modelling of mutational hotspots and in silico predictors in hypertrophic cardiomyopathy

por Waring, Adam, Harper, Andrew, Salatino, Silvia, Kramer, Christopher, Neubauer, Stefan, Thomson, Kate, Watkins, Hugh, Farrall, Martin
Publicado 2021

Hypertrophic cardiomyopathy mutations increase myofilament Ca(2+) buffering, alter intracellular Ca(2+) handling, and stimulate Ca(2+)-dependent signaling

por Robinson, Paul, Liu, Xing, Sparrow, Alexander, Patel, Suketu, Zhang, Yin-Hua, Casadei, Barbara, Watkins, Hugh, Redwood, Charles
Publicado 2018

Arrhythmogenic right ventricular cardiomyopathy type 6 (ARVC6): support for the locus assignment, narrowing of the critical region and mutation screening of three candidate genes

por Matolweni, Luzuko O, Bardien, Soraya, Rebello, George, Oppon, Ekow, Munclinger, Miroslav, Ramesar, Rajkumar, Watkins, Hugh, Mayosi, Bongani M
Publicado 2006

Plasma cytokines and risk of coronary heart disease in the PROCARDIS study

por Clarke, Robert, Valdes-Marquez, Elsa, Hill, Michael, Gordon, Joanne, Farrall, Martin, Hamsten, Anders, Watkins, Hugh, Hopewell, Jemma C
Publicado 2018