Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer

por Sokač, Mateo, Ahrenfeldt, Johanne, Litchfield, Kevin, Watkins, Thomas B.K., Knudsen, Michael, Dyrskjøt, Lars, Jakobsen, Martin R., Birkbak, Nicolai J.
Publicado 2022

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

por McGranahan, Nicholas, Rosenthal, Rachel, Hiley, Crispin T., Rowan, Andrew J., Watkins, Thomas B.K., Wilson, Gareth A., Birkbak, Nicolai J., Veeriah, Selvaraju, Van Loo, Peter, Herrero, Javier, Swanton, Charles
Publicado 2017

Quantifying the impact of immunotherapy on RNA dynamics in cancer

por Usaite, Ieva, Biswas, Dhruva, Dijkstra, Krijn, Watkins, Thomas BK, Pich, Oriol, Puttick, Clare, Angelova, Mihaela, Thakkar, Krupa, Hiley, Crispin, Birkbak, Nicolai, Kok, Marleen, Zaccaria, Simone, Wu, Yin, Litchfield, Kevin, Swanton, Charles, Kanu, Nnennaya
Publicado 2023

Expansion of airway basal epithelial cells from primary human non‐small cell lung cancer tumors

por Hynds, Robert E., Ben Aissa, Assma, Gowers, Kate H.C., Watkins, Thomas B.K., Bosshard‐Carter, Leticia, Rowan, Andrew J., Veeriah, Selvaraju, Wilson, Gareth A., Quezada, Sergio A., Swanton, Charles, Janes, Sam M.
Publicado 2018

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

por Litchfield, Kevin, Reading, James L., Puttick, Clare, Thakkar, Krupa, Abbosh, Chris, Bentham, Robert, Watkins, Thomas B.K., Rosenthal, Rachel, Biswas, Dhruva, Rowan, Andrew, Lim, Emilia, Al Bakir, Maise, Turati, Virginia, Guerra-Assunção, José Afonso, Conde, Lucia, Furness, Andrew J.S., Saini, Sunil Kumar, Hadrup, Sine R., Herrero, Javier, Lee, Se-Hoon, Van Loo, Peter, Enver, Tariq, Larkin, James, Hellmann, Matthew D., Turajlic, Samra, Quezada, Sergio A., McGranahan, Nicholas, Swanton, Charles
Publicado 2021

Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers

por Blakely, Collin M., Watkins, Thomas B.K., Wu, Wei, Gini, Beatrice, Chabon, Jacob J., McCoach, Caroline E., McGranahan, Nicholas, Wilson, Gareth A., Birkbak, Nicolai J., Olivas, Victor R., Rotow, Julia, Maynard, Ashley, Wang, Victoria, Gubens, Matthew A., Banks, Kimberly C., Lanman, Richard B., Caulin, Aleah F., John, John St., Cordero, Anibal R., Giannikopoulos, Petros, Simmons, Andrew D., Mack, Philip C., Gandara, David R., Husain, Hatim, Doebele, Robert C., Riess, Jonathan W., Diehn, Maximilian, Swanton, Charles, Bivona, Trever G.
Publicado 2017

Evolutionary characterisation of lung adenocarcinoma morphology in TRACERx

por Karasaki, Takahiro, Moore, David A., Veeriah, Selvaraju, Naceur-Lombardelli, Cristina, Toncheva, Antonia, Magno, Neil, Ward, Sophia, Al Bakir, Maise, Watkins, Thomas B.K., Grigoriadis, Kristiana, Huebner, Ariana, Hill, Mark S., Frankell, Alexander M., Abbosh, Christopher, Gimeno-Valiente, Francisco, Saghafinia, Sadegh, Kanu, Nnennaya, Dietzen, Michelle, Pich, Oriol, Lim, Emilia, Martinez-Ruiz, Carlos, Black, James R.M., Puttick, Clare, Biswas, Dhruva, Campbell, Brittany B., Lee, Claudia, Colliver, Emma, Enfield, Katey S.S., Hessey, Sonya, Hiley, Crispin T., Zaccaria, Simone, Litchfield, Kevin, Birkbak, Nicolai J., Cadieux, Elizabeth Larose, Demeulemeester, Jonas, Van Loo, Peter, Adusumilli, Prasad S., Tan, Kay See, Cheema, Waseem, Sanchez-Vega, Francisco, Jones, David R., Rekhtman, Natasha, Travis, William D., Hackshaw, Allan, Marafioti, Teresa, Salgado, Roberto, Le Quesne, John, Nicholson, Andrew G., McGranahan, Nicholas, Swanton, Charles, Jamal-Hanjani, Mariam, Jamal-Hanjani, Mariam, McGranahan, Nicholas, Swanton, Charles, McGranahan, Nicholas, Birkbak, Nicolai J., Litchfield, Kevin, Zaccaria, Simone, Swanton, Charles, Karasaki, Takahiro, Moore, David A., Al Bakir, Maise, Campbell, Brittany B., Abbosh, Christopher, Hessey, Sonya, Hiley, Crispin T., Jamal-Hanjani, Mariam, Swanton, Charles, Hackshaw, Allan, Moore, David A., Nicholson, Andrew G., Le Quesne, John, Salgado, Roberto, Al Bakir, Maise, Karasaki, Takahiro, Veeriah, Selvaraju, Naceur-Lombardelli, Cristina, Toncheva, Antonia, Magno, Neil, Ward, Sophia, Karasaki, Takahiro, Moore, David A., Dietzen, Michelle, Karasaki, Takahiro, Grigoriadis, Kristiana, Frankell, Alexander M., Watkins, Thomas B.K., Lim, Emilia, Hill, Mark S., Campbell, Brittany B., Karasaki, Takahiro, Martinez-Ruiz, Carlos, Black, James R.M., Puttick, Clare, Biswas, Dhruva, Gimeno-Valiente, Francisco, Saghafinia, Sadegh, Kanu, Nnennaya, Karasaki, Takahiro, Huebner, Ariana, Al Bakir, Maise, Abbosh, Christopher, Frankell, Alexander M., Karasaki, Takahiro, Birkbak, Nicolai J., Swanton, Charles, Karasaki, Takahiro, Puttick, Clare, Pich, Oriol, Puttick, Clare, Lee, Claudia, Grigoriadis, Kristiana, Colliver, Emma, Enfield, Katey S.S., Hiley, Crispin T., McGranahan, Nicholas, Swanton, Charles, Karasaki, Takahiro, Hill, Mark S., Litchfield, Kevin, Hackshaw, Allan, Adusumilli, Prasad S., Tan, Kay See, Cheema, Waseem, Sanchez-Vega, Francisco, Jones, David R., Rekhtman, Natasha, Travis, William D., Moore, David A., Karasaki, Takahiro, Watkins, Thomas B.K., Frankell, Alexander M., Grigoriadis, Kristiana, Colliver, Emma, Enfield, Katey S.S., Cadieux, Elizabeth Larose, Demeulemeester, Jonas, Van Loo, Peter, Sanchez-Vega, Francisco, Jones, David R., Rekhtman, Natasha, Travis, William D., Marafioti, Teresa, Salgado, Roberto, Le Quesne, John, Nicholson, Andrew G., McGranahan, Nicholas, Jamal-Hanjani, Mariam, Swanton, Charles
Publicado 2023

Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal

por Turajlic, Samra, Xu, Hang, Litchfield, Kevin, Rowan, Andrew, Chambers, Tim, Lopez, Jose I., Nicol, David, O’Brien, Tim, Larkin, James, Horswell, Stuart, Stares, Mark, Au, Lewis, Jamal-Hanjani, Mariam, Challacombe, Ben, Chandra, Ashish, Hazell, Steve, Eichler-Jonsson, Claudia, Soultati, Aspasia, Chowdhury, Simon, Rudman, Sarah, Lynch, Joanna, Fernando, Archana, Stamp, Gordon, Nye, Emma, Jabbar, Faiz, Spain, Lavinia, Lall, Sharanpreet, Guarch, Rosa, Falzon, Mary, Proctor, Ian, Pickering, Lisa, Gore, Martin, Watkins, Thomas B.K., Ward, Sophia, Stewart, Aengus, DiNatale, Renzo, Becerra, Maria F., Reznik, Ed, Hsieh, James J., Richmond, Todd A., Mayhew, George F., Hill, Samantha M., McNally, Catherine D., Jones, Carol, Rosenbaum, Heidi, Stanislaw, Stacey, Burgess, Daniel L., Alexander, Nelson R., Swanton, Charles
Publicado 2018

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

por Dentro, Stefan C., Leshchiner, Ignaty, Haase, Kerstin, Tarabichi, Maxime, Wintersinger, Jeff, Deshwar, Amit G., Yu, Kaixian, Rubanova, Yulia, Macintyre, Geoff, Demeulemeester, Jonas, Vázquez-García, Ignacio, Kleinheinz, Kortine, Livitz, Dimitri G., Malikic, Salem, Donmez, Nilgun, Sengupta, Subhajit, Anur, Pavana, Jolly, Clemency, Cmero, Marek, Rosebrock, Daniel, Schumacher, Steven E., Fan, Yu, Fittall, Matthew, Drews, Ruben M., Yao, Xiaotong, Watkins, Thomas B.K., Lee, Juhee, Schlesner, Matthias, Zhu, Hongtu, Adams, David J., McGranahan, Nicholas, Swanton, Charles, Getz, Gad, Boutros, Paul C., Imielinski, Marcin, Beroukhim, Rameen, Sahinalp, S. Cenk, Ji, Yuan, Peifer, Martin, Martincorena, Inigo, Markowetz, Florian, Mustonen, Ville, Yuan, Ke, Gerstung, Moritz, Spellman, Paul T., Wang, Wenyi, Morris, Quaid D., Wedge, David C., Van Loo, Peter
Publicado 2021

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

por Turajlic, Samra, Xu, Hang, Litchfield, Kevin, Rowan, Andrew, Horswell, Stuart, Chambers, Tim, O’Brien, Tim, Lopez, Jose I., Watkins, Thomas B.K., Nicol, David, Stares, Mark, Challacombe, Ben, Hazell, Steve, Chandra, Ashish, Mitchell, Thomas J., Au, Lewis, Eichler-Jonsson, Claudia, Jabbar, Faiz, Soultati, Aspasia, Chowdhury, Simon, Rudman, Sarah, Lynch, Joanna, Fernando, Archana, Stamp, Gordon, Nye, Emma, Stewart, Aengus, Xing, Wei, Smith, Jonathan C., Escudero, Mickael, Huffman, Adam, Matthews, Nik, Elgar, Greg, Phillimore, Ben, Costa, Marta, Begum, Sharmin, Ward, Sophia, Salm, Max, Boeing, Stefan, Fisher, Rosalie, Spain, Lavinia, Navas, Carolina, Grönroos, Eva, Hobor, Sebastijan, Sharma, Sarkhara, Aurangzeb, Ismaeel, Lall, Sharanpreet, Polson, Alexander, Varia, Mary, Horsfield, Catherine, Fotiadis, Nicos, Pickering, Lisa, Schwarz, Roland F., Silva, Bruno, Herrero, Javier, Luscombe, Nick M., Jamal-Hanjani, Mariam, Rosenthal, Rachel, Birkbak, Nicolai J., Wilson, Gareth A., Pipek, Orsolya, Ribli, Dezso, Krzystanek, Marcin, Csabai, Istvan, Szallasi, Zoltan, Gore, Martin, McGranahan, Nicholas, Van Loo, Peter, Campbell, Peter, Larkin, James, Swanton, Charles
Publicado 2018