Counterintuitive effect of antiviral therapy on influenza A-SARS-CoV-2 coinfection due to viral interference

por Cheemarla, Nagarjuna R., Mihaylova, Valia T., Watkins, Timothy A., Foxman, Ellen F.
Publicado 2023

1646. Combined Resistance Analyses From Phase 2b Studies of Presatovir Treatment in RSV-Infected Adults

por Porter, Danielle, Guo, Ying, Perry, Jason, Gossage, David, Watkins, Timothy, Chien, Jason, Jordan, Robert
Publicado 2018

Red blood cell transfusion and outcomes in patients with acute lung injury, sepsis and shock

por Parsons, Elizabeth C, Hough, Catherine L, Seymour, Christopher W, Cooke, Colin R, Rubenfeld, Gordon D, Watkins, Timothy R
Publicado 2011

Pharmacokinetics, pharmacodynamics, safety and tolerability of cilofexor, a novel nonsteroidal Farnesoid X receptor agonist, in healthy volunteers

por Younis, Islam R., Kirby, Brian J., Billin, Andrew N., Xiao, Deqing, Song, Qinghua, Watkins, Timothy R., Othman, Ahmed A.
Publicado 2023

Evaluation of the Potential for Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions for Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor (FXR) Agonist

por Younis, Islam, Weber, Elijah, Nelson, Cara, Kirby, Brian J., Shen, Gong, Xiao, Deqing, Watkins, Timothy R., Othman, Ahmed A.
Publicado 2023

Temperature and time stability of whole blood lactate: implications for feasibility of pre-hospital measurement

por Seymour, Christopher W, Carlbom, David, Cooke, Colin R, Watkins, Timothy R, Bulger, Eileen M, Rea, Thomas D, Baird, Geoffrey S
Publicado 2011

The effect of an intensive care unit staffing model on tidal volume in patients with acute lung injury

por Cooke, Colin R, Watkins, Timothy R, Kahn, Jeremy M, Treggiari, Miriam M, Caldwell, Ellen, Hudson, Leonard D, Rubenfeld, Gordon D
Publicado 2008

Magnitude and timing of the antiviral response determine SARS-CoV-2 replication early in infection

por Cheemarla, Nagarjuna R., Watkins, Timothy A., Mihaylova, Valia T., Wang, Bao, Zhao, Dejian, Wang, Guilin, Landry, Marie L., Foxman, Ellen F.
Publicado 2021

Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics

por Cheemarla, Nagarjuna R., Watkins, Timothy A., Mihaylova, Valia T., Wang, Bao, Zhao, Dejian, Wang, Guilin, Landry, Marie L., Foxman, Ellen F.
Publicado 2021

Development and validation of a prehospital prediction model for acute traumatic coagulopathy

por Peltan, Ithan D., Rowhani-Rahbar, Ali, Vande Vusse, Lisa K., Caldwell, Ellen, Rea, Thomas D., Maier, Ronald V., Watkins, Timothy R.
Publicado 2016

Supplemental Oxygen–Free Days in Hematopoietic Cell Transplant Recipients With Respiratory Syncytial Virus

por Waghmare, Alpana, Xie, Hu, Kimball, Louise, Yi, Jessica, Özkök, Sezen, Leisenring, Wendy, Cheng, Guang-Shing, Englund, Janet A, Watkins, Timothy R, Chien, Jason W, Boeckh, Michael
Publicado 2017

Alveolar levels of immuno-inflammatory mediators in diffuse alveolar hemorrhage after allogeneic transplant

por Vande Vusse, Lisa K., Wurfel, Mark M., Madtes, David M., Schoch, H. Gary, Harju-Baker, Susanna, Hill, Joshua A., Jerome, Keith R., Boeckh, Michael, Watkins, Timothy R.
Publicado 2018

MANTA and MANTA-RAy: Rationale and Design of Trials Evaluating Effects of Filgotinib on Semen Parameters in Patients with Inflammatory Diseases

por Hellstrom, Wayne J. G., Dolhain, Radboud J. E. M., Ritter, Timothy E., Watkins, Timothy R., Arterburn, Sarah J., Dekkers, Goele, Gillen, Angi, Tonussi, Caroline, Gilles, Leen, Oortwijn, Alessandra, Van Beneden, Katrien, de Vries, Dick E., Sikka, Suresh C., Vanderschueren, Dirk, Reinisch, Walter
Publicado 2022

Nasal host response-based screening for undiagnosed respiratory viruses: a pathogen surveillance and detection study

por Cheemarla, Nagarjuna R, Hanron, Amelia, Fauver, Joseph R, Bishai, Jason, Watkins, Timothy A, Brito, Anderson F, Zhao, Dejian, Alpert, Tara, Vogels, Chantal B F, Ko, Albert I, Schulz, Wade L, Landry, Marie L, Grubaugh, Nathan D, van Dijk, David, Foxman, Ellen F
Publicado 2023

Effects of filgotinib on semen parameters and sex hormones in male patients with inflammatory diseases: results from the phase 2, randomised, double-blind, placebo-controlled MANTA...

por Reinisch, Walter, Hellstrom, Wayne, Dolhain, Radboud J E M, Sikka, Suresh, Westhovens, René, Mehta, Rajiv, Ritter, Timothy, Seidler, Ursula, Golovchenko, Oleksandr, Simanenkov, Vladimir, Garmish, Olena, Jeka, Sławomir, Moravcová, Radka, Rajendran, Vijay, Le Brun, Franck-Olivier, Arterburn, Sarah, Watkins, Timothy R, Besuyen, Robin, Vanderschueren, Dirk
Publicado 2023

A Phase 2b, Randomized, Double-blind, Placebo-Controlled Multicenter Study Evaluating Antiviral Effects, Pharmacokinetics, Safety, and Tolerability of Presatovir in Hematopoietic C...

por Marty, Francisco M, Chemaly, Roy F, Mullane, Kathleen M, Lee, Dong-Gun, Hirsch, Hans H, Small, Catherine B, Bergeron, Anne, Shoham, Shmuel, Ljungman, Per, Waghmare, Alpana, Blanchard, Elodie, Kim, Yae-Jean, McKevitt, Matt, Porter, Danielle P, Jordan, Robert, Guo, Ying, German, Polina, Boeckh, Michael, Watkins, Timothy R, Chien, Jason W, Dadwal, Sanjeet S
Publicado 2019

Application of B cell immortalization for the isolation of antibodies and B cell clones from vaccine and infection settings

por Boswell, Kristin L., Watkins, Timothy A., Cale, Evan M., Samsel, Jakob, Andrews, Sarah F., Ambrozak, David R., Driscoll, Jefferson I., Messina, Michael A., Narpala, Sandeep, Hopp, Christine S., Cagigi, Alberto, Casazza, Joseph P., Yamamoto, Takuya, Zhou, Tongqing, Schief, William R., Crompton, Peter D., Ledgerwood, Julie E., Connors, Mark, Gama, Lucio, Kwong, Peter D., McDermott, Adrian, Mascola, John R., Koup, Richard A.
Publicado 2022

AI-based histologic scoring enables automated and reproducible assessment of enrollment criteria and endpoints in NASH clinical trials

por Iyer, Janani S., Pokkalla, Harsha, Biddle-Snead, Charles, Carrasco-Zevallos, Oscar, Lin, Mary, Shanis, Zahil, Le, Quang, Juyal, Dinkar, Pouryahya, Maryam, Pedawi, Aryan, Hoffman, Sara, Elliott, Hunter, Leidal, Kenneth, Myers, Robert P., Chung, Chuhan, Billin, Andrew N., Watkins, Timothy R., Resnick, Murray, Wack, Katy, Glickman, Jon, Burt, Alastair D., Loomba, Rohit, Sanyal, Arun J., Montalto, Michael C., Beck, Andrew H., Taylor-Weiner, Amaro, Wapinski, Ilan
Publicado 2023

A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial of Presatovir for the Treatment of Respiratory Syncytial Virus Upper Respiratory Tract Infection in Hematopoietic-Cell...

por Chemaly, Roy F, Dadwal, Sanjeet S, Bergeron, Anne, Ljungman, Per, Kim, Yae-Jean, Cheng, Guang-Shing, Pipavath, Sudhakar N, Limaye, Ajit P, Blanchard, Elodie, Winston, Drew J, Stiff, Patrick J, Zuckerman, Tsila, Lachance, Silvy, Rahav, Galia, Small, Catherine B, Mullane, Kathleen M, Patron, Roberto L, Lee, Dong-Gun, Hirsch, Hans H, Waghmare, Alpana, McKevitt, Matt, Jordan, Robert, Guo, Ying, German, Polina, Porter, Danielle P, Gossage, David L, Watkins, Timothy R, Marty, Francisco M, Chien, Jason W, Boeckh, Michael
Publicado 2019