Modeling Alzheimer’s disease in primary neurons reveals DNA damage response coupled with MAPK-DLK signaling in wild-type tau-induced neurodegeneration

por Li, Sanming, Roy, Ethan R., Wang, Yanyu, Watkins, Trent, Cao, Wei
Publicado 2023

JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis

por Huntwork-Rodriguez, Sarah, Wang, Bei, Watkins, Trent, Ghosh, Arundhati Sengupta, Pozniak, Christine D., Bustos, Daisy, Newton, Kim, Kirkpatrick, Donald S., Lewcock, Joseph W.
Publicado 2013

Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult

por Larhammar, Martin, Huntwork-Rodriguez, Sarah, Jiang, Zhiyu, Solanoy, Hilda, Sengupta Ghosh, Arundhati, Wang, Bei, Kaminker, Joshua S, Huang, Kevin, Eastham-Anderson, Jeffrey, Siu, Michael, Modrusan, Zora, Farley, Madeline M, Tessier-Lavigne, Marc, Lewcock, Joseph W, Watkins, Trent A
Publicado 2017

Remyelination protects neurons from DLK-mediated neurodegeneration

por Duncan, Greg J, Ingram, Samantha D, Emberley, Katie, Hill, Jo, Cordano, Christian, Abdelhak, Ahmed, McCane, Michael, Jabassini, Nora, Ananth, Kirtana, Ferrara, Skylar J., Stedelin, Brittany, Sivyer, Benjamin, Aicher, Sue A., Scanlan, Thomas, Watkins, Trent A, Mishra, Anusha, Nelson, Jonathan, Green, Ari J., Emery, Ben
Publicado 2023