The Enteric Virome in Inflammatory Bowel Disease

por Brooks, Johanne, Watson, Alastair J.M.
Publicado 2015

Deciphering the Complex Signaling Systems That Regulate Intestinal Epithelial Cell Death Processes and Shedding

por Patterson, Angela M., Watson, Alastair J. M.
Publicado 2017

Modelling the Spatio-Temporal Cell Dynamics Reveals Novel Insights on Cell Differentiation and Proliferation in the Small Intestinal Crypt

por Pin, Carmen, Watson, Alastair J. M., Carding, Simon R.
Publicado 2012

Inhibition of Hsp90 acts synergistically with topoisomerase II poisons to increase the apoptotic killing of cells due to an increase in topoisomerase II mediated DNA damage

por Barker, Catherine R., McNamara, Anne V., Rackstraw, Stephen A., Nelson, David E., White, Mike R., Watson, Alastair J. M., Jenkins, John R.
Publicado 2006

A hierarchical Bayesian model for understanding the spatiotemporal dynamics of the intestinal epithelium

por Maclaren, Oliver J., Parker, Aimée, Pin, Carmen, Carding, Simon R., Watson, Alastair J. M., Fletcher, Alexander G., Byrne, Helen M., Maini, Philip K.
Publicado 2017

Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi

por Parker, Aimee, Maclaren, Oliver J., Fletcher, Alexander G., Muraro, Daniele, Kreuzaler, Peter A., Byrne, Helen M., Maini, Philip K., Watson, Alastair J. M., Pin, Carmen
Publicado 2017

Elevated apoptosis impairs epithelial cell turnover and shortens villi in TNF-driven intestinal inflammation

por Parker, Aimée, Vaux, Laura, Patterson, Angela M., Modasia, Amisha, Muraro, Daniele, Fletcher, Alexander G., Byrne, Helen M., Maini, Philip K., Watson, Alastair J. M., Pin, Carmen
Publicado 2019

Calcium Elevation in Mitochondria Is the Main Ca(2+) Requirement for Mitochondrial Permeability Transition Pore (mPTP) Opening

por Baumgartner, Heidi K., Gerasimenko, Julia V., Thorne, Christopher, Ferdek, Pawel, Pozzan, Tullio, Tepikin, Alexei V., Petersen, Ole H., Sutton, Robert, Watson, Alastair J. M., Gerasimenko, Oleg V.
Publicado 2009

The early life microbiota protects neonatal mice from pathological small intestinal epithelial cell shedding

por Hughes, Kevin R., Schofield, Zoe, Dalby, Matthew J., Caim, Shabhonam, Chalklen, Lisa, Bernuzzi, Federico, Alcon‐Giner, Cristina, Le Gall, Gwénaëlle, Watson, Alastair J. M., Hall, Lindsay J.
Publicado 2020

Caspase-8 controls the gut response to microbial challenges by Tnf-α-dependent and independent pathways

por Günther, Claudia, Buchen, Barbara, He, Gui-Wei, Hornef, Mathias, Torow, Natalia, Neumann, Helmut, Wittkopf, Nadine, Martini, Eva, Basic, Marijana, Bleich, André, Watson, Alastair J M, Neurath, Markus F, Becker, Christoph
Publicado 2015

Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

por Marchiando, Amanda M., Shen, Le, Graham, W. Vallen, Weber, Christopher R., Schwarz, Brad T., Austin, Jotham R., Raleigh, David R., Guan, Yanfang, Watson, Alastair J.M., Montrose, Marshall H., Turner, Jerrold R.
Publicado 2010

Confocal laser endomicroscopy is a new imaging modality for recognition of intramucosal bacteria in inflammatory bowel disease in vivo

por Moussata, Driffa, Goetz, Martin, Gloeckner, Annabel, Kerner, Marcus, Campbell, Barry, Hoffman, Arthur, Biesterfeld, Stephan, Flourie, Bernard, Saurin, Jean-Christophe, Galle, Peter R, Neurath, Markus F, Watson, Alastair J M, Kiesslich, Ralf
Publicado 2010

A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide

por Williams, Jonathan M., Duckworth, Carrie A., Watson, Alastair J. M., Frey, Mark R., Miguel, Jennifer C., Burkitt, Michael D., Sutton, Robert, Hughes, Kevin R., Hall, Lindsay J., Caamaño, Jorge H., Campbell, Barry J., Pritchard, D. Mark
Publicado 2013

Dietary Supplementation with Soluble Plantain Non-Starch Polysaccharides Inhibits Intestinal Invasion of Salmonella Typhimurium in the Chicken

por Parsons, Bryony N., Wigley, Paul, Simpson, Hannah L., Williams, Jonathan M., Humphrey, Suzie, Salisbury, Anne-Marie, Watson, Alastair J. M., Fry, Stephen C., O'Brien, David, Roberts, Carol L., O'Kennedy, Niamh, Keita, Åsa V., Söderholm, Johan D., Rhodes, Jonathan M., Campbell, Barry J.
Publicado 2014

Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy

por Jones, Emily J., Matthews, Zoe J., Gul, Lejla, Sudhakar, Padhmanand, Treveil, Agatha, Divekar, Devina, Buck, Jasmine, Wrzesinski, Tomasz, Jefferson, Matthew, Armstrong, Stuart D., Hall, Lindsay J., Watson, Alastair J. M., Carding, Simon R., Haerty, Wilfried, Di Palma, Federica, Mayer, Ulrike, Powell, Penny P., Hautefort, Isabelle, Wileman, Tom, Korcsmaros, Tamas
Publicado 2019

Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation

por Martínez-Sánchez, Luz del Carmen, Ngo, Phuong Anh, Pradhan, Rashmita, Becker, Lukas-Sebastian, Boehringer, David, Soteriou, Despina, Kubankova, Marketa, Schweitzer, Christine, Koch, Tatyana, Thonn, Veronika, Erkert, Lena, Stolzer, Iris, Günther, Claudia, Becker, Christoph, Weigmann, Benno, Klewer, Monika, Daniel, Christoph, Amann, Kerstin, Tenzer, Stefan, Atreya, Raja, Bergo, Martin, Brakebusch, Cord, Watson, Alastair J M, Guck, Jochen, Fabry, Ben, Atreya, Imke, Neurath, Markus F, López-Posadas, Rocío
Publicado 2023