Editorial: Adenylyl cyclase isoforms as potential drug targets

por Brust, Tarsis F., Ostrom, Rennolds S., Watts, Val J.
Publicado 2022

Dopamine D(2) Receptor-Mediated Heterologous Sensitization of AC5 Requires Signalosome Assembly

por Ejendal, Karin F. K., Dessauer, Carmen W., Hébert, Terence E., Watts, Val J.
Publicado 2012

Comparative pharmacological characterization of D(1)-like dopamine receptors from Anopheles gambiae, Aedes aegypti and Culex quinquefasciatus suggests pleiotropic signaling in mosq...

por Hill, Catherine A., Doyle, Trevor, Nuss, Andrew B., Ejendal, Karin F. K., Meyer, Jason M., Watts, Val J.
Publicado 2016

Isoform Specific Regulation of Adenylyl Cyclase 5 by Gβγ

por Yen, Yu-Chen, Li, Yong, Chen, Chun-Liang, Klose, Thomas, Watts, Val J, Dessauer, Carmen W, Tesmer, John J. G.
Publicado 2023

Reduced activity of adenylyl cyclase 1 attenuates morphine induced hyperalgesia and inflammatory pain in mice

por Johnson, Kayla, Doucette, Alexis, Edwards, Alexis, Verdi, Aleeya, McFarland, Ryan, Hulke, Shelby, Fowler, Amanda, Watts, Val J., Klein, Amanda H.
Publicado 2022

Dopamine Receptor Antagonists as New Mode-of-Action Insecticide Leads for Control of Aedes and Culex Mosquito Vectors

por Nuss, Andrew B., Ejendal, Karin F. K., Doyle, Trevor B., Meyer, Jason M., Lang, Emma G., Watts, Val J., Hill, Catherine A.
Publicado 2015

Protein-protein interaction-based high throughput screening for adenylyl cyclase 1 inhibitors: Design, implementation, and discovery of a novel chemotype

por Dwyer, Tiffany S., O’Brien, Joseph B., Ptak, Christopher P., LaVigne, Justin E., Flaherty, Daniel P., Watts, Val J., Roman, David L.
Publicado 2022

Identification of Novel Adenylyl Cyclase 5 (AC5) Signaling Networks in D(1) and D(2) Medium Spiny Neurons using Bimolecular Fluorescence Complementation Screening

por Doyle, Trevor B., Muntean, Brian S., Ejendal, Karin F., Hayes, Michael P., Soto-Velasquez, Monica, Martemyanov, Kirill A., Dessauer, Carmen W., Hu, Chang-Deng, Watts, Val J.
Publicado 2019

AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca(2+) Channels

por Kar, Pulak, Barak, Pradeep, Zerio, Anna, Lin, Yu-Ping, Parekh, Amy J, Watts, Val J, Cooper, Dermot M F, Zaccolo, Manuela, Kramer, Holger, Parekh, Anant B
Publicado 2021

A “Genome-to-Lead” Approach for Insecticide Discovery: Pharmacological Characterization and Screening of Aedes aegypti D(1)-like Dopamine Receptors

por Meyer, Jason M., Ejendal, Karin F. K., Avramova, Larisa V., Garland-Kuntz, Elisabeth E., Giraldo-Calderón, Gloria I., Brust, Tarsis F., Watts, Val J., Hill, Catherine A.
Publicado 2012