Rationale and Means to Target Pro-Inflammatory Interleukin-8 (CXCL8) Signaling in Cancer

por Campbell, Laura M., Maxwell, Pamela J., Waugh, David J.J.
Publicado 2013

Tumor-derived CXCL8 signaling augments stroma-derived CCL2-promoted proliferation and CXCL12-mediated invasion of PTEN-deficient prostate cancer cells

por Maxwell, Pamela J., Neisen, Jessica, Messenger, Johanna, Waugh, David J.J.
Publicado 2014

CD44-mediated activation of α5β1-integrin, cortactin and paxillin signaling underpins adhesion of basal-like breast cancer cells to endothelium and Fibronectin-enriched matrices

por McFarlane, Suzanne, McFarlane, Cheryl, Montgomery, Nicola, Hill, Ashleigh, Waugh, David J.J.
Publicado 2015

CD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity

por Montgomery, Nicola, Hill, Ashleigh, McFarlane, Suzanne, Neisen, Jessica, O'Grady, Anthony, Conlon, Susie, Jirstrom, Karin, Kay, Elaine W, Waugh, David JJ
Publicado 2012

CD44 increases the efficiency of distant metastasis of breast cancer

por McFarlane, Suzanne, Coulter, Jonathan A., Tibbits, Paul, O'Grady, Anthony, McFarlane, Cheryl, Montgomery, Nicola, Hill, Ashleigh, McCarthy, Helen O., Young, Leonie S., Kay, Elaine W., Isacke, Clare M., Waugh, David J.J.
Publicado 2015

Attenuating Adaptive VEGF-A and IL8 Signaling Restores Durable Tumor Control in AR Antagonist–Treated Prostate Cancers

por Maxwell, Pamela J., McKechnie, Melanie, Armstrong, Christopher W., Manley, Judith M., Ong, Chee Wee, Worthington, Jenny, Mills, Ian G., Longley, Daniel B., Quigley, James P., Zoubeidi, Amina, de Bono, Johann S., Deryugina, Elena, LaBonte, Melissa J., Waugh, David J.J.
Publicado 2022

PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy

por Armstrong, Chris W.D., Maxwell, Pamela J., Ong, Chee Wee, Redmond, Kelly M., McCann, Christopher, Neisen, Jessica, Ward, George A., Chessari, Gianni, Johnson, Christopher, Crawford, Nyree T., LaBonte, Melissa J., Prise, Kevin M., Robson, Tracy, Salto-Tellez, Manuel, Longley, Daniel B., Waugh, David J.J.
Publicado 2016

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.

por D'Costa, Zenobia C., Higgins, Catherine, Ong, Chee Wee, Irwin, Gareth W., Boyle, David, McArt, Darragh G., McCloskey, Karen, Buckley, Niamh E., Crawford, Nyree T., Thiagarajan, Lalitha, Murray, James T., Kennedy, Richard D., Mulligan, Karl A., Harkin, D. Paul, Waugh, David J.J., Scott, Chris J., Salto-Tellez, Manuel, Williams, Richard, Mullan, Paul B.
Publicado 2014