Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR

por Simons, Jan Fredrik, Lim, Yoong Wearn, Carter, Kyle P., Wagner, Ellen K., Wayham, Nicholas, Adler, Adam S., Johnson, David S.
Publicado 2020

Antibody repertoire analysis of mouse immunization protocols using microfluidics and molecular genomics

por Asensio, Michael A., Lim, Yoong Wearn, Wayham, Nicholas, Stadtmiller, Kacy, Edgar, Robert C., Leong, Jackson, Leong, Renee, Mizrahi, Rena A., Adams, Matthew S., Simons, Jan Fredrik, Spindler, Matthew J., Johnson, David S., Adler, Adam S.
Publicado 2019

Detection of Clonal and Subclonal Copy-Number Variants in Cell-Free DNA from Patients with Breast Cancer Using a Massively Multiplexed PCR Methodology

por Kirkizlar, Eser, Zimmermann, Bernhard, Constantin, Tudor, Swenerton, Ryan, Hoang, Bin, Wayham, Nicholas, Babiarz, Joshua E., Demko, Zachary, Pelham, Robert J., Kareht, Stephanie, Simon, Alexander L., Jinnett, Kristine N., Rabinowitz, Matthew, Sigurjonsson, Styrmir, Hill, Matthew
Publicado 2015

Preferential Identification of Agonistic OX40 Antibodies by Using Cell Lysate to Pan Natively Paired, Humanized Mouse-Derived Yeast Surface Display Libraries

por Medina-Cucurella, Angélica V., Mizrahi, Rena A., Asensio, Michael A., Edgar, Robert C., Leong, Jackson, Leong, Renee, Lim, Yoong Wearn, Nelson, Ayla, Niedecken, Ariel R., Simons, Jan Fredrik, Spindler, Matthew J., Stadtmiller, Kacy, Wayham, Nicholas, Adler, Adam S., Johnson, David S.
Publicado 2019

A Potent Recombinant Polyclonal Antibody Therapeutic for Protection Against New Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern

por Wayham, Nicholas P, Niedecken, Ariel R, Simons, Jan Fredrik, Chiang, Yao Y, Medina-Cucurella, Angélica V, Mizrahi, Rena A, Wagner, Ellen K, Gras, Ashley, Segal, Ilana, Witte, Peyton, Enstrom, Alexis, Bountouvas, Aristea, Nelson, Sabrina M, Weinberger, Tess, Tan, David, Asensio, Michael A, Subramanian, Alagu, Lim, Yoong Wearn, Adler, Adam S, Keating, Sheila M
Publicado 2023

GMP Manufacturing and IND-Enabling Studies of a Recombinant Hyperimmune Globulin Targeting SARS-CoV-2

por Mizrahi, Rena A., Lin, Wendy Y., Gras, Ashley, Niedecken, Ariel R., Wagner, Ellen K., Keating, Sheila M., Ikon, Nikita, Manickam, Vishal A., Asensio, Michael A., Leong, Jackson, Medina-Cucurella, Angelica V., Benzie, Emily, Carter, Kyle P., Chiang, Yao, Edgar, Robert C., Leong, Renee, Lim, Yoong Wearn, Simons, Jan Fredrik, Spindler, Matthew J., Stadtmiller, Kacy, Wayham, Nicholas, Büscher, Dirk, Terencio, Jose Vicente, Germanio, Clara Di, Chamow, Steven M., Olson, Charles, Pino, Paula A., Park, Jun-Gyu, Hicks, Amberlee, Ye, Chengjin, Garcia-Vilanova, Andreu, Martinez-Sobrido, Luis, Torrelles, Jordi B., Johnson, David S., Adler, Adam S.
Publicado 2022

Generation of recombinant hyperimmune globulins from diverse B-cell repertoires

por Keating, Sheila M., Mizrahi, Rena A., Adams, Matthew S., Asensio, Michael A., Benzie, Emily, Carter, Kyle P., Chiang, Yao, Edgar, Robert C., Gautam, Bishal K., Gras, Ashley, Leong, Jackson, Leong, Renee, Wearn Lim, Yoong, Manickam, Vishal A., Medina-Cucurella, Angelica V., Niedecken, Ariel R., Saini, Jasmeen, Fredrik Simons, Jan, Spindler, Matthew J., Stadtmiller, Kacy, Tinsley, Brendan, Wagner, Ellen K., Wayham, Nicholas, Tracy, LaRee, Vingsbo Lundberg, Carina, Büscher, Dirk, Vicente Terencio, Jose, Roalfe, Lucy, Pearce, Emma, Richardson, Hayley, Goldblatt, David, Ramjag, Anushka T., Carrington, Christine V.F., Simmons, Graham, Muench, Marcus O., Chamow, Steven M., Monroe, Bryan, Olson, Charles, Oguin, Thomas H., Lynch, Heather, Jeanfreau, Robert, Mosher, Rachel A., Walch, Matthew J., Bartley, Christopher R., Ross, Carl A., Meyer, Everett H., Adler, Adam S., Johnson, David S.
Publicado 2021