How Taxol/paclitaxel kills cancer cells

por Weaver, Beth A.
Publicado 2014

The role of aneuploidy in promoting and suppressing tumors

por Weaver, Beth A.A., Cleveland, Don W.
Publicado 2009

Low Rates of Aneuploidy Promote Tumorigenesis while High Rates of Aneuploidy Cause Cell Death and Tumor Suppression

por Weaver, Beth A. A., Silk, Alain D., Cleveland, Don W.
Publicado 2008

Recordings from neuron–HEK cell cocultures reveal the determinants of miniature excitatory postsynaptic currents

por Chiang, Chung-Wei, Shu, Wen-Chi, Wan, Jun, Weaver, Beth A., Jackson, Meyer B.
Publicado 2021

Quantifying chromosomal instability from intratumoral karyotype diversity using agent-based modeling and Bayesian inference

por Lynch, Andrew R, Arp, Nicholas L, Zhou, Amber S, Weaver, Beth A, Burkard, Mark E
Publicado 2022

The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B

por Britigan, Eric M.C., Wan, Jun, Zasadil, Lauren M., Ryan, Sean D., Weaver, Beth A.
Publicado 2014

Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer

por Denu, Ryan A., Zasadil, Lauren M., Kanugh, Craig, Laffin, Jennifer, Weaver, Beth A., Burkard, Mark E.
Publicado 2016

Mad1 destabilizes p53 by preventing PML from sequestering MDM2

por Wan, Jun, Block, Samuel, Scribano, Christina M., Thiry, Rebecca, Esbona, Karla, Audhya, Anjon, Weaver, Beth A.
Publicado 2019

A survey of CIN measures across mechanistic models

por Lynch, Andrew R., Bradford, Shermineh, Zhou, Amber S., Oxendine, Kim, Henderson, Les, Horner, Vanessa L., Weaver, Beth A., Burkard, Mark E.
Publicado 2023

High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instabilit...

por Matson, Daniel R., Denu, Ryan A., Zasadil, Lauren M., Burkard, Mark E., Weaver, Beth A., Flynn, Christopher, Stukenberg, P. Todd
Publicado 2021

Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss

por Weaver, Beth A.A., Bonday, Zahid Q., Putkey, Frances R., Kops, Geert J.P.L., Silk, Alain D., Cleveland, Don W.
Publicado 2003

Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer

por Tucker, John B., Bonema, Sarah C., García-Varela, Rebeca, Denu, Ryan A., Hu, Yang, McGregor, Stephanie M., Burkard, Mark E., Weaver, Beth A.
Publicado 2023

ZW10 links mitotic checkpoint signaling to the structural kinetochore

por Kops, Geert J.P.L., Kim, Yumi, Weaver, Beth A.A., Mao, Yinghui, McLeod, Ian, Yates, John R., Tagaya, Mitsuo, Cleveland, Don W.
Publicado 2005

High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation

por Zasadil, Lauren M., Britigan, Eric M. C., Ryan, Sean D., Kaur, Charanjeet, Guckenberger, David J., Beebe, David J., Moser, Amy R., Weaver, Beth A.
Publicado 2016

Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles

por Zhou, Amber S., Tucker, John B., Scribano, Christina M., Lynch, Andrew R., Carlsen, Caleb L., Pop-Vicas, Sophia T., Pattaswamy, Srishrika M., Burkard, Mark E., Weaver, Beth A.
Publicado 2023

Centrosome amplification is a frequent event in circulating tumor cells from subjects with metastatic breast cancer

por Singh, Ashok, Denu, Ryan A., Wolfe, Serena K., Sperger, Jamie M., Schehr, Jennifer, Witkowsky, Tessa, Esbona, Karla, Chappell, Richard J., Weaver, Beth A., Burkard, Mark E., Lang, Joshua M.
Publicado 2020

Increased Aurora B expression reduces substrate phosphorylation and induces chromosomal instability

por Britigan, Eric M. C., Wan, Jun, Sam, Daniel K., Copeland, Sarah E., Lasek, Amber L., Hrycyniak, Laura C. F., Wang, Lei, Audhya, Anjon, Burkard, Mark E., Roopra, Avtar, Weaver, Beth A.
Publicado 2022

HPV16 E6 induces chromosomal instability due to polar chromosomes caused by E6AP-dependent degradation of the mitotic kinesin CENP-E

por Cosper, Pippa F., Hrycyniak, Laura C. F., Paracha, Maha, Lee, Denis L., Wan, Jun, Jones, Kathryn, Bice, Sophie A., Nickel, Kwangok, Mallick, Samyukta, Taylor, Alison M., Kimple, Randall J., Lambert, Paul F., Weaver, Beth A.
Publicado 2023

Therapeutic relevance of the protein phosphatase 2A in cancer

por Cunningham, Chelsea E., Li, Shuangshuang, Vizeacoumar, Frederick S., Bhanumathy, Kalpana Kalyanasundaram, Lee, Joo Sang, Parameswaran, Sreejit, Furber, Levi, Abuhussein, Omar, Paul, James M., McDonald, Megan, Templeton, Shaina D., Shukla, Hersh, El Zawily, Amr M., Boyd, Frederick, Alli, Nezeka, Mousseau, Darrell D., Geyer, Ron, Bonham, Keith, Anderson, Deborah H., Yan, Jiong, Yu-Lee, Li-Yuan, Weaver, Beth A., Uppalapati, Maruti, Ruppin, Eytan, Sablina, Anna, Freywald, Andrew, Vizeacoumar, Franco J.
Publicado 2016