The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment

por Weaver, Jeremy D., Wang, Huanchen, Shears, Stephen B.
Publicado 2013

First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP(5) kinase

por Riley, Andrew M., Wang, Huanchen, Weaver, Jeremy D., Shears, Stephen B., Potter, Barry V. L.
Publicado 2012

Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery

por Wang, Huanchen, Godage, Himali Y., Riley, Andrew M., Weaver, Jeremy D., Shears, Stephen B., Potter, Barry V.L.
Publicado 2014

Human Genome-Wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response

por Pulloor, Niyas Kudukkil, Nair, Sajith, Kostic, Aleksandar D., Bist, Pradeep, Weaver, Jeremy D., Riley, Andrew M., Tyagi, Richa, Uchil, Pradeep D., York, John D., Snyder, Solomon H., García-Sastre, Adolfo, Potter, Barry V. L., Lin, Rongtuan, Shears, Stephen B., Xavier, Ramnik J., Krishnan, Manoj N.
Publicado 2014