Engineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease

por Johnson, Matthew J., Laoharawee, Kanut, Lahr, Walker S., Webber, Beau R., Moriarity, Branden S.
Publicado 2018

254 A systems genomics approach to identify novel drug targets of Ewing sarcoma through ancestry-informed human iPSC modeling

por Moss, Rachel M, Becklin, Kelsie, Mills, Lauren J, Moriarity, Branden S, Webber, Beau R, Spector, Logan G
Publicado 2023

Dermatopontin in Bone Marrow Extracellular Matrix Regulates Adherence but Is Dispensable for Murine Hematopoietic Cell Maintenance

por Kramer, Ashley C., Blake, Amanda L., Taisto, Mandy E., Lehrke, Michael J., Webber, Beau R., Lund, Troy C.
Publicado 2017

EditR: A Method to Quantify Base Editing from Sanger Sequencing

por Kluesner, Mitchell G., Nedveck, Derek A., Lahr, Walker S., Garbe, John R., Abrahante, Juan E., Webber, Beau R., Moriarity, Branden S.
Publicado 2018

MultiEditR: The first tool for the detection and quantification of RNA editing from Sanger sequencing demonstrates comparable fidelity to RNA-seq

por Kluesner, Mitchell G., Tasakis, Rafail Nikolaos, Lerner, Taga, Arnold, Annette, Wüst, Sandra, Binder, Marco, Webber, Beau R., Moriarity, Branden S., Pecori, Riccardo
Publicado 2021

CRISPR/Cas9-Mediated Correction of the FANCD1 Gene in Primary Patient Cells

por Skvarova Kramarzova, Karolina, Osborn, Mark J., Webber, Beau R., DeFeo, Anthony P., McElroy, Amber N., Kim, Chong Jai, Tolar, Jakub
Publicado 2017

Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays

por Kurata, Morito, Wolf, Natalie K., Lahr, Walker S., Weg, Madison T., Kluesner, Mitchell G., Lee, Samantha, Hui, Kai, Shiraiwa, Masano, Webber, Beau R., Moriarity, Branden S.
Publicado 2018

Myosin Heavy Chain Converter Domain Mutations Drive Early-Stage Changes in Extracellular Matrix Dynamics in Hypertrophic Cardiomyopathy

por Hsieh, Jeanne, Becklin, Kelsie L., Givens, Sophie, Komosa, Elizabeth R., Lloréns, Juan E. Abrahante, Kamdar, Forum, Moriarity, Branden S., Webber, Beau R., Singh, Bhairab N., Ogle, Brenda M.
Publicado 2022

Rapid DNA replication origin licensing protects stem cell pluripotency

por Matson, Jacob Peter, Dumitru, Raluca, Coryell, Philip, Baxley, Ryan M, Chen, Weili, Twaroski, Kirk, Webber, Beau R, Tolar, Jakub, Bielinsky, Anja-Katrin, Purvis, Jeremy E, Cook, Jeanette Gowen
Publicado 2017

Correction: Rapid DNA replication origin licensing protects stem cell pluripotency

por Matson, Jacob Peter, Dumitru, Raluca, Coryell, Philip, Baxley, Ryan M, Chen, Weili, Twaroski, Kirk, Webber, Beau R, Tolar, Jakub, Bielinsky, Anja-Katrin, Purvis, Jeremy E, Cook, Jeanette Gowen
Publicado 2019

Germline T cell receptor exchange results in physiological T cell development and function

por Rollins, Meagan R., Raynor, Jackson F., Miller, Ebony A., Butler, Jonah Z., Spartz, Ellen J., Lahr, Walker S., You, Yun, Burrack, Adam L., Moriarity, Branden S., Webber, Beau R., Stromnes, Ingunn M.
Publicado 2023

A Pan-RNase Inhibitor Enabling CRISPR-mRNA Platforms for Engineering of Primary Human Monocytes

por Laoharawee, Kanut, Johnson, Matthew J., Lahr, Walker S., Sipe, Christopher J., Kleinboehl, Evan, Peterson, Joseph J., Lonetree, Cara-lin, Bell, Jason B., Slipek, Nicholas J., Crane, Andrew T., Webber, Beau R., Moriarity, Branden S.
Publicado 2022

A BAFF ligand-based CAR-T cell targeting three receptors and multiple B cell cancers

por Wong, Derek P., Roy, Nand K., Zhang, Keman, Anukanth, Anusha, Asthana, Abhishek, Shirkey-Son, Nicole J., Dunmire, Samantha, Jones, Bryan J., Lahr, Walker S., Webber, Beau R., Moriarity, Branden S., Caimi, Paolo, Parameswaran, Reshmi
Publicado 2022

CRISPR/Cas9-Based Cellular Engineering for Targeted Gene Overexpression

por Osborn, Mark J., Lees, Christopher J., McElroy, Amber N., Merkel, Sarah C., Eide, Cindy R., Mathews, Wendy, Feser, Colby J., Tschann, Madison, McElmury, Ron T., Webber, Beau R., Kim, Chong Jai, Blazar, Bruce R., Tolar, Jakub
Publicado 2018

Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments

por Tabdanov, Erdem D., Rodríguez-Merced, Nelson J., Cartagena-Rivera, Alexander X., Puram, Vikram V., Callaway, Mackenzie K., Ensminger, Ethan A., Pomeroy, Emily J., Yamamoto, Kenta, Lahr, Walker S., Webber, Beau R., Moriarity, Branden S., Zhovmer, Alexander S., Provenzano, Paolo P.
Publicado 2021

Rapid generation of Col7a1(−/−) mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells

por Webber, Beau R., O’Connor, Kyle T., McElmurry, Ron T., Durgin, Elise N., Eide, Cindy, Lees, Christopher J., Riddle, Megan J., Mathews, Wendy, Frank, Natasha Y., Kluth, Mark A., Ganss, Christoph, Moriarity, Branden S., Frank, Markus H., Osborn, Mark J., Tolar, Jakub
Publicado 2017

CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa

por Webber, Beau R, Osborn, Mark J, McElroy, Amber N, Twaroski, Kirk, Lonetree, Cara-lin, DeFeo, Anthony P, Xia, Lily, Eide, Cindy, Lees, Christopher J, McElmurry, Ron T, Riddle, Megan J, Kim, Chong Jai, Patel, Dharmeshkumar D, Blazar, Bruce R, Tolar, Jakub
Publicado 2016

CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells

por Kluesner, Mitchell G., Lahr, Walker S., Lonetree, Cara-lin, Smeester, Branden A., Qiu, Xiaohong, Slipek, Nicholas J., Claudio Vázquez, Patricia N., Pitzen, Samuel P., Pomeroy, Emily J., Vignes, Madison J., Lee, Samantha C., Bingea, Samuel P., Andrew, Aneesha A., Webber, Beau R., Moriarity, Branden S.
Publicado 2021

Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors

por Webber, Beau R., Lonetree, Cara-lin, Kluesner, Mitchell G., Johnson, Matthew J., Pomeroy, Emily J., Diers, Miechaleen D., Lahr, Walker S., Draper, Garrett M., Slipek, Nicholas J., Smeester, Branden A., Lovendahl, Klaus N., McElroy, Amber N., Gordon, Wendy R., Osborn, Mark J., Moriarity, Branden S.
Publicado 2019

Author Correction: Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors

por Webber, Beau R., Lonetree, Cara-lin, Kluesner, Mitchell G., Johnson, Matthew J., Pomeroy, Emily J., Diers, Miechaleen D., Lahr, Walker S., Draper, Garrett M., Slipek, Nicholas J., Smeester, Branden A., Lovendahl, Klaus N., McElroy, Amber N., Gordon, Wendy R., Osborn, Mark J., Moriarity, Branden S.
Publicado 2019