Targeting the NLRP3 Inflammasome via BTK

por Weber, Alexander N. R.
Publicado 2021

Fish TLR5 develops a taste for viral RNA

por Weber, Alexander N R
Publicado 2022

Gadd45a Is an RNA Binding Protein and Is Localized in Nuclear Speckles

por Sytnikova, Yuliya A., Kubarenko, Andriy V., Schäfer, Andrea, Weber, Alexander N. R., Niehrs, Christof
Publicado 2011

Delayed NLRP3 inflammasome inhibition ameliorates subacute stroke progression in mice

por Bellut, Maximilian, Bieber, Michael, Kraft, Peter, Weber, Alexander N. R., Stoll, Guido, Schuhmann, Michael K.
Publicado 2023

Bruton’s Tyrosine Kinase: An Emerging Key Player in Innate Immunity

por Weber, Alexander N. R., Bittner, Zsofia, Liu, Xiao, Dang, Truong-Minh, Radsak, Markus Philipp, Brunner, Cornelia
Publicado 2017

Neutrophils: Between Host Defence, Immune Modulation, and Tissue Injury

por Kruger, Philipp, Saffarzadeh, Mona, Weber, Alexander N. R., Rieber, Nikolaus, Radsak, Markus, von Bernuth, Horst, Benarafa, Charaf, Roos, Dirk, Skokowa, Julia, Hartl, Dominik
Publicado 2015

Two Human MYD88 Variants, S34Y and R98C, Interfere with MyD88-IRAK4-Myddosome Assembly

por George, Julie, Motshwene, Precious G., Wang, Hui, Kubarenko, Andriy V., Rautanen, Anna, Mills, Tara C., Hill, Adrian V. S., Gay, Nicholas J., Weber, Alexander N. R.
Publicado 2011

Modulation of the CD95-Induced Apoptosis: The Role of CD95 N-Glycosylation

por Shatnyeva, Olga M., Kubarenko, Andriy V., Weber, Claudia E. M., Pappa, Alexander, Schwartz-Albiez, Reinhard, Weber, Alexander N. R., Krammer, Peter H., Lavrik, Inna N.
Publicado 2011

Absence of Non-Canonical, Inhibitory MYD88 Splice Variants in B Cell Lymphomas Correlates With Sustained NF-κB Signaling

por Cardona Gloria, Yamel, Bernhart, Stephan H., Fillinger, Sven, Wolz, Olaf-Oliver, Dickhöfer, Sabine, Admard, Jakob, Ossowski, Stephan, Nahnsen, Sven, Siebert, Reiner, Weber, Alexander N. R.
Publicado 2021

The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold

por Dossang, Anthony C. G., Motshwene, Precious G., Yang, Yang, Symmons, Martyn F., Bryant, Clare E., Borman, Satty, George, Julie, Weber, Alexander N. R., Gay, Nicholas J.
Publicado 2016

Crucial Role of Nucleic Acid Sensing via Endosomal Toll-Like Receptors for the Defense of Streptococcus pyogenes in vitro and in vivo

por Hafner, Anna, Kolbe, Ulrike, Freund, Isabel, Castiglia, Virginia, Kovarik, Pavel, Poth, Tanja, Herster, Franziska, Weigand, Markus A., Weber, Alexander N. R., Dalpke, Alexander H., Eigenbrod, Tatjana
Publicado 2019

The role of FIBCD1 in response to Aspergillus fumigatus in lung epithelial cells

por Bhattacharya, Shreya, Maupin, Alec Jacob, Schlosser, Anders Grønnegaard, Füchtbauer, Ernst-Martin, Gloria, Yamel Cardona, Weber, Alexander N. R., Holmskov, Uffe, Moeller, Jesper Bonnet, Templeton, Steven P.
Publicado 2023

Pattern recognition receptor mediated downregulation of microRNA‐650 fine‐tunes MxA expression in dendritic cells infected with influenza A virus

por Pichulik, Tica, Khatamzas, Elham, Liu, Xiao, Brain, Oliver, Delmiro Garcia, Magno, Leslie, Alasdair, Danis, Benedicte, Mayer, Alice, Baban, Dilair, Ragoussis, Jiannis, Weber, Alexander N. R., Simmons, Alison
Publicado 2015

A Naturally Occurring Variant in Human TLR9, P99L, Is Associated with Loss of CpG Oligonucleotide Responsiveness

por Kubarenko, Andriy V., Ranjan, Satish, Rautanen, Anna, Mills, Tara C., Wong, Sunny, Vannberg, Fredrik, Neumaier, Michael, Bekeredjian-Ding, Isabelle, Hill, Adrian V. S., Ahmad-Nejad, Parviz, Weber, Alexander N. R.
Publicado 2010

Investigation of single and synergic effects of NLRC5 and PD-L1 variants on the risk of colorectal cancer

por Catalano, Calogerina, da Silva Filho, Miguel Inacio, Frank, Christoph, Jiraskova, Katerina, Vymetalkova, Veronika, Levy, Miroslav, Liska, Vaclav, Vycital, Ondrej, Naccarati, Alessio, Vodickova, Ludmila, Hemminki, Kari, Vodicka, Pavel, Weber, Alexander N. R., Försti, Asta
Publicado 2018

Epistatic effect of TLR3 and cGAS‐STING‐IKKε‐TBK1‐IFN signaling variants on colorectal cancer risk

por Catalano, Calogerina, da Silva Filho, Miguel Inacio, Frank, Christoph, Lu, Shun, Jiraskova, Katerina, Vymetalkova, Veronika, Levy, Miroslav, Liska, Vaclav, Vycital, Ondrej, Naccarati, Alessio, Vodickova, Ludmila, Hemminki, Kari, Vodicka, Pavel, Weber, Alexander N. R., Försti, Asta
Publicado 2019

Study of Human RIG-I Polymorphisms Identifies Two Variants with an Opposite Impact on the Antiviral Immune Response

por Pothlichet, Julien, Burtey, Anne, Kubarenko, Andriy V., Caignard, Gregory, Solhonne, Brigitte, Tangy, Frédéric, Ben-Ali, Meriem, Quintana-Murci, Lluis, Heinzmann, Andrea, Chiche, Jean-Daniel, Vidalain, Pierre-Olivier, Weber, Alexander N. R., Chignard, Michel, Si-Tahar, Mustapha
Publicado 2009

Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis

por Herster, Franziska, Bittner, Zsofia, Codrea, Marius Cosmin, Archer, Nathan K., Heister, Martin, Löffler, Markus W., Heumos, Simon, Wegner, Joanna, Businger, Ramona, Schindler, Michael, Stegner, David, Schäkel, Knut, Grabbe, Stephan, Ghoreschi, Kamran, Miller, Lloyd S., Weber, Alexander N. R.
Publicado 2019

NLRP3 Inflammasome Assembly in Neutrophils Is Supported by PAD4 and Promotes NETosis Under Sterile Conditions

por Münzer, Patrick, Negro, Roberto, Fukui, Shoichi, di Meglio, Lucas, Aymonnier, Karen, Chu, Long, Cherpokova, Deya, Gutch, Sarah, Sorvillo, Nicoletta, Shi, Lai, Magupalli, Venkat Giri, Weber, Alexander N. R., Scharf, Rüdiger E., Waterman, Clare M., Wu, Hao, Wagner, Denisa D.
Publicado 2021

Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells

por El Maadidi, Souhayla, Weber, Alexander N. R., Motshwene, Precious, Schüssler, Jan Moritz, Backes, Daniel, Dickhöfer, Sabine, Wang, Hui, Liu, Xiao, Garcia, Magno Delmiro, Taumer, Christoph, Soufi, Boumediene, Wolz, Olaf-Oliver, Klimosch, Sascha N., Franz-Wachtel, Mirita, Macek, Boris, Gay, Nicholas J.
Publicado 2019