Safety, tolerability and pharmacodynamics of a novel immunomodulator, MIS416, in patients with chronic progressive multiple sclerosis

por Luckey, Alison M, Anderson, Tim, Silverman, Michael H, Webster, Gill
Publicado 2015

Innate IFN-γ ameliorates experimental autoimmune encephalomyelitis and promotes myeloid expansion and PDL-1 expression

por White, Madeleine P. J., Webster, Gill, Leonard, Faith, La Flamme, Anne Camille
Publicado 2018

Targeting Innate Receptors with MIS416 Reshapes Th Responses and Suppresses CNS Disease in a Mouse Model of Multiple Sclerosis

por White, Madeleine, Webster, Gill, O’Sullivan, David, Stone, Sarrabeth, La Flamme, Anne Camille
Publicado 2014

Bridging Small Molecules to Modified Bacterial Microparticles Using a Disulphide Linkage: MIS416 as a Cargo Delivery System

por Mainini, Francesco, Larsen, David S., Webster, Gill A., Young, Sarah L., Eccles, Michael R.
Publicado 2015

Evaluation of neurological changes in secondary progressive multiple sclerosis patients treated with immune modulator MIS416: results from a feasibility study

por Webster, Gill A., Sim, Dalice A., La Flamme, Anne C., Mayo, Nancy E.
Publicado 2017

MIS416 as a siRNA Delivery System with the Ability to Target Antigen-Presenting Cells

por Mainini, Francesco, Larsen, David S., Webster, Gill A., Young, Sarah L., Eccles, Michael R.
Publicado 2018

Innate Signaling in the CNS Prevents Demyelination in a Focal EAE Model

por Dubik, Magdalena, Marczynska, Joanna, Mørch, Marlene T., Webster, Gill, Jensen, Kirstine Nolling, Wlodarczyk, Agnieszka, Khorooshi, Reza, Owens, Trevor
Publicado 2021

Potent subunit-specific effects on cell growth and drug sensitivity from optimised siRNA-mediated silencing of ribonucleotide reductase

por Reid, Glen, Wallant, Natacha Coppieters ‘t, Patel, Rachna, Antonic, Ana, Saxon-Aliifaalogo, Faamatala, Cao, Helen, Webster, Gill, Watson, James D
Publicado 2009

MIS416 Enhances Therapeutic Functions of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Against Experimental Colitis by Modulating Systemic Immune Milieu

por Lee, Byung-Chul, Shin, Nari, Lee, Jin Young, Kang, Insung, Kim, Jae-Jun, Lee, Seung Eun, Choi, Soon Won, Webster, Gill A., Kang, Kyung-Sun
Publicado 2018

Innate signaling within the central nervous system recruits protective neutrophils

por Khorooshi, Reza, Marczynska, Joanna, Dieu, Ruthe Storgaard, Wais, Vian, Hansen, Christian Rønn, Kavan, Stephanie, Thomassen, Mads, Burton, Mark, Kruse, Torben, Webster, Gill A., Owens, Trevor
Publicado 2020

Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade in ovarian cancer

por McGray, A. J. Robert, Huang, Ruea-Yea, Battaglia, Sebastiano, Eppolito, Cheryl, Miliotto, Anthony, Stephenson, Kyle B., Lugade, Amit A., Webster, Gill, Lichty, Brian D., Seshadri, Mukund, Kozbor, Danuta, Odunsi, Kunle
Publicado 2019

Targeting myeloid cells in the tumor microenvironment enhances vaccine efficacy in murine epithelial ovarian cancer

por Khan, Anm Nazmul H., Kolomeyevskaya, Nonna, Singel, Kelly L., Grimm, Melissa J., Moysich, Kirsten B., Daudi, Sayeema, Grzankowski, Kassondra S., Lele, Sashikant, Ylagan, Lourdes, Webster, Gill A., Abrams, Scott I., Odunsi, Kunle, Segal, Brahm H.
Publicado 2015

First-in-human phase I clinical trial of the NY-ESO-1 protein cancer vaccine with NOD2 and TLR9 stimulants in patients with NY-ESO-1-expressing refractory solid tumors

por Ishihara, Mikiya, Tono, Yasutaka, Miyahara, Yoshihiro, Muraoka, Daisuke, Harada, Naozumi, Kageyama, Shinichi, Sasaki, Takeshi, Hori, Yasuhide, Soga, Norihito, Uchida, Katsunori, Shiraishi, Taizo, Sato, Eiichi, Kanda, Hideki, Mizuno, Toshiro, Webster, Gill A., Ikeda, Hiroaki, Katayama, Naoyuki, Sugimura, Yoshiki, Shiku, Hiroshi
Publicado 2020