Structure of a class II preQ(1) riboswitch reveals ligand recognition by a new fold

por Liberman, Joseph A., Salim, Mohammad, Krucinska, Jolanta, Wedekind, Joseph E.
Publicado 2013

Structure and function analysis of a type III preQ(1)-I riboswitch from Escherichia coli reveals direct metabolite sensing by the Shine-Dalgarno sequence

por Schroeder, Griffin M., Kiliushik, Daniil, Jenkins, Jermaine L., Wedekind, Joseph E.
Publicado 2023

A posteriori design of crystal contacts to improve the X-ray diffraction properties of a small RNA enzyme

por MacElrevey, Celeste, Spitale, Robert C., Krucinska, Jolanta, Wedekind, Joseph E.
Publicado 2007

Molecular mechanism for preQ(1)-II riboswitch function revealed by molecular dynamics

por Aytenfisu, Asaminew H., Liberman, Joseph A., Wedekind, Joseph E., Mathews, David H.
Publicado 2015

Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors

por Chavali, Sai Shashank, Mali, Sachitanand M., Jenkins, Jermaine L., Fasan, Rudi, Wedekind, Joseph E.
Publicado 2021

Evidence for the Role of Active Site Residues in the Hairpin Ribozyme from Molecular Simulations along the Reaction Path

por Heldenbrand, Hugh, Janowski, Pawel A., Giambaşu, George, Giese, Timothy J., Wedekind, Joseph E., York, Darrin M.
Publicado 2014

Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing

por Srivastava, Yoshita, Bonn-Breach, Rachel, Chavali, Sai Shashank, Lippa, Geoffrey M., Jenkins, Jermaine L., Wedekind, Joseph E.
Publicado 2021

A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control

por Schroeder, Griffin M., Cavender, Chapin E., Blau, Maya E., Jenkins, Jermaine L., Mathews, David H., Wedekind, Joseph E.
Publicado 2022

Analysis of a preQ(1)-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation

por Schroeder, Griffin M, Dutta, Debapratim, Cavender, Chapin E, Jenkins, Jermaine L, Pritchett, Elizabeth M, Baker, Cameron D, Ashton, John M, Mathews, David H, Wedekind, Joseph E
Publicado 2020

Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription

por Belashov, Ivan A, Crawford, David W, Cavender, Chapin E, Dai, Peng, Beardslee, Patrick C, Mathews, David H, Pentelute, Bradley L, McNaughton, Brian R, Wedekind, Joseph E
Publicado 2018

A riboswitch separated from its ribosome-binding site still regulates translation

por Schroeder, Griffin M, Akinyemi, Olayinka, Malik, Jeffrey, Focht, Caroline M, Pritchett, Elizabeth M, Baker, Cameron D, McSally, James P, Jenkins, Jermaine L, Mathews, David H, Wedekind, Joseph E
Publicado 2023

Single transcriptional and translational preQ(1) riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure

por Suddala, Krishna C., Rinaldi, Arlie J., Feng, Jun, Mustoe, Anthony M., Eichhorn, Catherine D., Liberman, Joseph A., Wedekind, Joseph E., Al-Hashimi, Hashim M., Brooks, Charles L., Walter, Nils G.
Publicado 2013