MBNL1 alternative splicing isoforms play opposing roles in cancer

por Tabaglio, Tommaso, Low, Diana HP, Teo, Winnie Koon Lay, Goy, Pierre Alexis, Cywoniuk, Piotr, Wollmann, Heike, Ho, Jessica, Tan, Damien, Aw, Joey, Pavesi, Andrea, Sobczak, Krzysztof, Wee, Dave Keng Boon, Guccione, Ernesto
Publicado 2018

Splice‐switch oligonucleotide‐based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC‐driven hepatocellular carcinoma

por Thng, Dexter Kai Hao, Toh, Tan Boon, Pigini, Paolo, Hooi, Lissa, Dan, Yock Young, Chow, Pierce Kah‐Hoe, Bonney, Glenn Kunnath, Rashid, Masturah Bte Mohd Abdul, Guccione, Ernesto, Wee, Dave Keng Boon, Chow, Edward Kai‐Hua
Publicado 2022

HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness

por Ho, Jessica SY, Di Tullio, Federico, Schwarz, Megan, Low, Diana, Incarnato, Danny, Gay, Florence, Tabaglio, Tommaso, Zhang, JingXian, Wollmann, Heike, Chen, Leilei, An, Omer, Chan, Tim Hon Man, Hall Hickman, Alexander, Zheng, Simin, Roudko, Vladimir, Chen, Sujun, Karz, Alcida, Ahmed, Musaddeque, He, Housheng Hansen, Greenbaum, Benjamin D, Oliviero, Salvatore, Serresi, Michela, Gargiulo, Gaetano, Mann, Karen M, Hernando, Eva, Mulholland, David, Marazzi, Ivan, Wee, Dave Keng Boon, Guccione, Ernesto
Publicado 2021