Adenovirus Transcriptome in Human Cells Infected with  ChAdOx1-Vectored Candidate HIV-1 Vaccine Is Dominated by High Levels of Correctly Spliced HIVconsv1&62 Transgene RNA

por Matthews, David A., Milligan, Rachel, Wee, Edmund G., Hanke, Tomáš
Publicado 2023

Effect of epitope variant co-delivery on the depth of CD8 T cell responses induced by HIV-1 conserved mosaic vaccines

por Wee, Edmund G., Moyo, Nathifa, Hannoun, Zara, Giorgi, Elena E., Korber, Bette, Hanke, Tomáš
Publicado 2021

Adenovirus DNA Polymerase Loses Fidelity on a Stretch of Eleven Homocytidines during Pre-GMP Vaccine Preparation

por Hannoun, Zara, Wee, Edmund G., Crook, Alison, Colloca, Stefano, Di Marco, Stefania, Hanke, Tomáš
Publicado 2022

Combined intranasal and intramuscular parainfluenza 5-, simian adenovirus ChAdOx1- and poxvirus MVA-vectored vaccines induce synergistically HIV-1-specific T cells in the mucosa

por Beavis, Ashley C., Wee, Edmund G. -T., Akis Yildirim, Belkis M., Borthwick, Nicola, He, Biao, Hanke, Tomáš
Publicado 2023

Long-term follow up of human T-cell responses to conserved HIV-1 regions elicited by DNA/simian adenovirus/MVA vaccine regimens

por Moyo, Nathifa, Borthwick, Nicola J., Wee, Edmund G., Capucci, Silvia, Crook, Alison, Dorrell, Lucy, Hanke, Tomáš
Publicado 2017

Efficient Induction of T Cells against Conserved HIV-1 Regions by Mosaic Vaccines Delivered as Self-Amplifying mRNA

por Moyo, Nathifa, Vogel, Annette B., Buus, Søren, Erbar, Stephanie, Wee, Edmund G., Sahin, Ugur, Hanke, Tomáš
Publicado 2018

Priming With Recombinant BCG Expressing Novel HIV-1 Conserved Mosaic Immunogens and Boosting With Recombinant ChAdOx1 Is Safe, Stable, and Elicits HIV-1-Specific T-Cell Responses i...

por Kilpeläinen, Athina, Saubi, Narcís, Guitart, Núria, Moyo, Nathifa, Wee, Edmund G., Ravi, Krupa, Hanke, Tomáš, Joseph, Joan
Publicado 2019

HIV-1 Conserved Mosaics Delivered by Regimens with Integration-Deficient DC-Targeting Lentiviral Vector Induce Robust T Cells

por Wee, Edmund G., Ondondo, Beatrice, Berglund, Peter, Archer, Jacob, McMichael, Andrew J., Baltimore, David, ter Meulen, Jan H., Hanke, Tomáš
Publicado 2017

Tetravalent Immunogen Assembled from Conserved Regions of HIV-1 and Delivered as mRNA Demonstrates Potent Preclinical T-Cell Immunogenicity and Breadth

por Moyo, Nathifa, Wee, Edmund G., Korber, Bette, Bahl, Kapil, Falcone, Samantha, Himansu, Sunny, Wong, Adrianne L., Dey, Antu K., Feinberg, Mark, Hanke, Tomáš
Publicado 2020

Complete protection of the BALB/c and C57BL/6J mice against Ebola and Marburg virus lethal challenges by pan-filovirus T-cell epigraph vaccine

por Rahim, Md Niaz, Wee, Edmund G., He, Shihua, Audet, Jonathan, Tierney, Kevin, Moyo, Nathifa, Hannoun, Zara, Crook, Alison, Baines, Andrea, Korber, Bette, Qiu, Xiangguo, Hanke, Tomáš
Publicado 2019

Randomized phase I trial HIV-CORE 003: Depletion of serum amyloid P component and immunogenicity of DNA vaccination against HIV-1

por Borthwick, Nicola J., Lane, Thirusha, Moyo, Nathifa, Crook, Alison, Shim, Jung Min, Baines, Ian, Wee, Edmund G., Hawkins, Philip N., Gillmore, Julian D., Hanke, Tomáš, Pepys, Mark B.
Publicado 2018

Parallel Induction of CH505 B Cell Ontogeny-Guided Neutralizing Antibodies and tHIVconsvX Conserved Mosaic-Specific T Cells against HIV-1

por Wee, Edmund G., Moyo, Nathifa A., Saunders, Kevin O., LaBranche, Celia, Donati, Filippo, Capucci, Silvia, Parks, Robert, Borthwick, Nicola, Hannoun, Zara, Montefiori, David C., Haynes, Barton F., Hanke, Tomáš
Publicado 2019

Parallel Induction of CH505 B Cell Ontogeny-Guided Neutralizing Antibodies and tHIVconsvX Conserved Mosaic-Specific T Cells against HIV-1

por Wee, Edmund G., Moyo, Nathifa A., Saunders, Kevin O., LaBranche, Celia, Donati, Filippo, Capucci, Silvia, Parks, Robert, Borthwick, Nicola, Hannoun, Zara, Montefiori, David C., Haynes, Barton F., Hanke, Tomáš
Publicado 2022

Correction: HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

por Capucci, Silvia, Wee, Edmund G., Schiffner, Torben, LaBranche, Celia C., Borthwick, Nicola, Cupo, Albert, Dodd, Jonathan, Dean, Hansi, Sattentau, Quentin, Montefiori, David, Klasse, Per J., Sanders, Rogier W., Moore, John P., Hanke, Tomáš
Publicado 2023

HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

por Capucci, Silvia, Wee, Edmund G., Schiffner, Torben, LaBranche, Celia C., Borthwick, Nicola, Cupo, Albert, Dodd, Jonathan, Dean, Hansi, Sattentau, Quentin, Montefiori, David, Klasse, Per J., Sanders, Rogier W., Moore, John P., Hanke, Tomáš
Publicado 2017

Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study)

por Mothe, Beatriz, Manzardo, Christian, Sanchez-Bernabeu, Alvaro, Coll, Pep, Morón-López, Sara, Puertas, Maria C., Rosas-Umbert, Miriam, Cobarsi, Patricia, Escrig, Roser, Perez-Alvarez, Núria, Ruiz, Irene, Rovira, Cristina, Meulbroek, Michael, Crook, Alison, Borthwick, Nicola, Wee, Edmund G., Yang, Hongbing, Miró, Jose M., Dorrell, Lucy, Clotet, Bonaventura, Martinez-Picado, Javier, Brander, Christian, Hanke, Tomáš
Publicado 2019

Corrigendum to ‘Therapeutic vaccination refocuses T-cell responses towards conserved regions of HIV-1 in early treated individuals (BCN 01 study)’ EClinicalMedicine 11 (2019) 65–80...

por Mothe, Beatriz, Manzardo, Christian, Sanchez-Bernabeu, Alvaro, Coll, Pep, Morón-López, Sara, Puertas, Maria C., Rosas-Umbert, Miriam, Cobarsi, Patricia, Escrig, Roser, Perez-Alvarez, Núria, Ruiz, Irene, Rovira, Cristina, Meulbroek, Michael, Crook, Alison, Borthwick, Nicola, Wee, Edmund G., Yang, Hongbing, Miró, Jose M., Dorrell, Lucy, Clotet, Bonaventura, Martinez-Picado, Javier, Brander, Christian, Hanke, Tomáš
Publicado 2020

HIVconsv Vaccines and Romidepsin in Early-Treated HIV-1-Infected Individuals: Safety, Immunogenicity and Effect on the Viral Reservoir (Study BCN02)

por Mothe, Beatriz, Rosás-Umbert, Miriam, Coll, Pep, Manzardo, Christian, Puertas, Maria C., Morón-López, Sara, Llano, Anuska, Miranda, Cristina, Cedeño, Samandhy, López, Miriam, Alarcón-Soto, Yovaninna, Melis, Guadalupe Gómez, Langohr, Klaus, Barriocanal, Ana M., Toro, Jessica, Ruiz, Irene, Rovira, Cristina, Carrillo, Antonio, Meulbroek, Michael, Crook, Alison, Wee, Edmund G., Miró, Jose M., Clotet, Bonaventura, Valle, Marta, Martinez-Picado, Javier, Hanke, Tomáš, Brander, Christian, Moltó, José
Publicado 2020