Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency

por Bajrami, Ilirjana, Walker, Callum, Krastev, Dragomir B., Weekes, Daniel, Song, Feifei, Wicks, Andrew J., Alexander, John, Haider, Syed, Brough, Rachel, Pettitt, Stephen J., Tutt, Andrew N. J., Lord, Christopher J.
Publicado 2021

Regulation of osteosarcoma cell lung metastasis by the c-Fos/AP-1 target FGFR1

por Weekes, Daniel, Kashima, Takeshi G, Zandueta, Carolina, Perurena, Naiara, Thomas, David P, Sunters, Andrew, Vuillier, Céline, Bozec, Aline, El-Emir, Ethaar, Miletich, Isabelle, Patiño-Garcia, Ana, Lecanda, Fernando, Grigoriadis, Agamemnon E
Publicado 2015

Functional screening reveals HORMAD1-driven gene dependencies associated with translesion synthesis and replication stress tolerance

por Tarantino, Dalia, Walker, Callum, Weekes, Daniel, Pemberton, Helen, Davidson, Kathryn, Torga, Gonzalo, Frankum, Jessica, Mendes-Pereira, Ana M., Prince, Cynthia, Ferro, Riccardo, Brough, Rachel, Pettitt, Stephen J., Lord, Christopher J., Grigoriadis, Anita, NJ Tutt, Andrew
Publicado 2022

The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment

por Monteiro, Lara J., Khongkow, Pasarat, Kongsema, Mesayamas, Morris, Joanna R., Man, Cornelia, Weekes, Daniel, Koo, Chuay-Yeng, Gomes, Ana R., Pinto, Paola H., Varghese, Vidhya, Kenny, Laura M., Coombes, R. Charles, Freire, Raimundo, Medema, René H., Lam, Eric W.-F.
Publicado 2012

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

por Krastev, Dragomir B., Li, Shudong, Sun, Yilun, Wicks, Andrew J., Hoslett, Gwendoline, Weekes, Daniel, Badder, Luned M., Knight, Eleanor G., Marlow, Rebecca, Pardo, Mercedes Calvo, Yu, Lu, Talele, Tanaji T., Bartek, Jiri, Choudhary, Jyoti S., Pommier, Yves, Pettitt, Stephen J., Tutt, Andrew N. J., Ramadan, Kristijan, Lord, Christopher J.
Publicado 2022

Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer

por Patel, Nirmesh, Weekes, Daniel, Drosopoulos, Konstantinos, Gazinska, Patrycja, Noel, Elodie, Rashid, Mamun, Mirza, Hasan, Quist, Jelmar, Brasó-Maristany, Fara, Mathew, Sumi, Ferro, Riccardo, Pereira, Ana Mendes, Prince, Cynthia, Noor, Farzana, Francesch-Domenech, Erika, Marlow, Rebecca, de Rinaldis, Emanuele, Grigoriadis, Anita, Linardopoulos, Spiros, Marra, Pierfrancesco, Tutt, Andrew N. J.
Publicado 2018