Glycosphingolipids within membrane contact sites influence their function as signaling hubs in neurodegenerative diseases

por Weesner, Jason Andrew, Annunziata, Ida, van de Vlekkert, Diantha, d'Azzo, Alessandra
Publicado 2023

Generation of human induced pluripotent stem cells (hIPSCs) from sialidosis types I and II patients with pathogenic neuraminidase 1 mutations

por Han, Min-Joon, Annunziata, Ida, Weesner, Jason, Campos, Yvan, Salie, Muneeb, O’Reilly, Carla, d’Azzo, Alessandra
Publicado 2020

Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout mice

por Winter, Aimee N., Subbarayan, Meena S., Grimmig, Bethany, Weesner, Jason A., Moss, Lauren, Peters, Melinda, Weeber, Edwin, Nash, Kevin, Bickford, Paula C.
Publicado 2020

Distinct functions of dimeric and monomeric scaffold protein Alix in regulating F-actin assembly and loading of exosomal cargo

por Qiu, Xiaohui, Campos, Yvan, van de Vlekkert, Diantha, Gomero, Elida, Tanwar, Ajay C., Kalathur, Ravi, Weesner, Jason A., Bongiovanni, Antonella, Demmers, Jeroen, d’Azzo, Alessandra
Publicado 2022

AAV-mediated gene therapy for galactosialidosis: A long-term safety and efficacy study

por Hu, Huimin, Mosca, Rosario, Gomero, Elida, van de Vlekkert, Diantha, Campos, Yvan, Fremuth, Leigh E., Brown, Scott A., Weesner, Jason A., Annunziata, Ida, d’Azzo, Alessandra
Publicado 2021

Preclinical Enzyme Replacement Therapy with a Recombinant β-Galactosidase-Lectin Fusion for CNS Delivery and Treatment of GM1-Gangliosidosis

por Weesner, Jason Andrew, Annunziata, Ida, Yang, Tianhong, Acosta, Walter, Gomero, Elida, Hu, Huimin, van de Vlekkert, Diantha, Ayala, Jorge, Qiu, Xiaohui, Fremuth, Leigh Ellen, Radin, David N., Cramer, Carole L., d’Azzo, Alessandra
Publicado 2022

MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat

por Annunziata, Ida, van de Vlekkert, Diantha, Wolf, Elmar, Finkelstein, David, Neale, Geoffrey, Machado, Eda, Mosca, Rosario, Campos, Yvan, Tillman, Heather, Roussel, Martine F., Andrew Weesner, Jason, Ellen Fremuth, Leigh, Qiu, Xiaohui, Han, Min-Joon, Grosveld, Gerard C., d’Azzo, Alessandra
Publicado 2019