P440: ENHANCER HIJACKING IN COMPLEX-KARYOTYPE AML

por Sollier, Etienne, Riedel, Anna, Kelly, Katherine, Weichenhan, Dieter, Jahn, Ekaterina, Döhner, Konstanze, Döhner, Hartmut, Ernst, Aurélie, Lutsik, Pavlo, Plass, Christoph
Publicado 2023

Increased proinflammatory endothelial response to S100A8/A9 after preactivation through advanced glycation end products

por Ehlermann, Philipp, Eggers, Kai, Bierhaus, Angelika, Most, Patrick, Weichenhan, Dieter, Greten, Johannes, Nawroth, Peter P, Katus, Hugo A, Remppis, Andrew
Publicado 2006

Club cells employ regeneration mechanisms during lung tumorigenesis

por Chen, Yuanyuan, Toth, Reka, Chocarro, Sara, Weichenhan, Dieter, Hey, Joschka, Lutsik, Pavlo, Sawall, Stefan, Stathopoulos, Georgios T., Plass, Christoph, Sotillo, Rocio
Publicado 2022

Adverse events in families with hypertrophic or dilated cardiomyopathy and mutations in the MYBPC3 gene

por Ehlermann, Philipp, Weichenhan, Dieter, Zehelein, Jörg, Steen, Henning, Pribe, Regina, Zeller, Raphael, Lehrke, Stephanie, Zugck, Christian, Ivandic, Boris T, Katus, Hugo A
Publicado 2008

Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease

por Hey, Joschka, Paulsen, Michelle, Toth, Reka, Weichenhan, Dieter, Butz, Simone, Schatterny, Jolanthe, Liebers, Reinhard, Lutsik, Pavlo, Plass, Christoph, Mall, Marcus A.
Publicado 2021

Predictive value of DNA methylation patterns in AML patients treated with an azacytidine containing induction regimen

por Schmutz, Maximilian, Zucknick, Manuela, Schlenk, Richard F., Mertens, Daniel, Benner, Axel, Weichenhan, Dieter, Mücke, Oliver, Döhner, Konstanze, Plass, Christoph, Bullinger, Lars, Claus, Rainer
Publicado 2023

Neuronal ensemble-specific DNA methylation strengthens engram stability

por Gulmez Karaca, Kubra, Kupke, Janina, Brito, David V. C., Zeuch, Benjamin, Thome, Christian, Weichenhan, Dieter, Lutsik, Pavlo, Plass, Christoph, Oliveira, Ana M. M.
Publicado 2020

Fetal hemoglobin induction during decitabine treatment of elderly patients with high-risk myelodysplastic syndrome or acute myeloid leukemia: a potential dynamic biomarker of outco...

por Stomper, Julia, Ihorst, Gabriele, Suciu, Stefan, Sander, Philipp N., Becker, Heiko, Wijermans, Pierre W., Plass, Christoph, Weichenhan, Dieter, Bissé, Emmanuel, Claus, Rainer, Lübbert, Michael
Publicado 2019

DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis

por Souren, Nicole Y., Gerdes, Lisa A., Lutsik, Pavlo, Gasparoni, Gilles, Beltrán, Eduardo, Salhab, Abdulrahman, Kümpfel, Tania, Weichenhan, Dieter, Plass, Christoph, Hohlfeld, Reinhard, Walter, Jörn
Publicado 2019

The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium

por Schlereth, Katharina, Weichenhan, Dieter, Bauer, Tobias, Heumann, Tina, Giannakouri, Evangelia, Lipka, Daniel, Jaeger, Samira, Schlesner, Matthias, Aloy, Patrick, Eils, Roland, Plass, Christoph, Augustin, Hellmut G
Publicado 2018

Identification of Pparγ-modulated miRNA hubs that target the fibrotic tumor microenvironment

por Winkler, Ivana, Bitter, Catrin, Winkler, Sebastian, Weichenhan, Dieter, Thavamani, Abhishek, Hengstler, Jan G., Borkham-Kamphorst, Erawan, Kohlbacher, Oliver, Plass, Christoph, Geffers, Robert, Weiskirchen, Ralf, Nordheim, Alfred
Publicado 2020

Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression

por Boonsanay, Verawan, Mosa, Mohammed H., Looso, Mario, Weichenhan, Dieter, Ceteci, Fatih, Pudelko, Lorenz, Lechel, Andre, Michel, Christian S., Künne, Carsten, Farin, Henner F., Plass, Christoph, Greten, Florian R.
Publicado 2023

PB1808: EPIGENETIC INHIBITOR SCREEN TO IDENTIFY THERAPEUTIC CANDIDATES FOR MNX1-OVEREXPRESSING AML

por Kelekci, Simge, Riedel, Anna, Weichenhan, Dieter, Goyal, Ashish, Kelly, Katherine, Baehr, Marion, Michels, Birgitta, Koerner, Cindy, Orzella, Irene, Dunford, James, Lutsik, Pavlo, Wiemann, Stefan, Oppermann, Udo, Plass, Christoph
Publicado 2023

Indirect epigenetic testing identifies a diagnostic signature of cardiomyocyte DNA methylation in heart failure

por Oeing, Christian U., Pepin, Mark E., Saul, Kerstin B., Agircan, Ayça Seyhan, Assenov, Yassen, Merkel, Tobias S., Sedaghat-Hamedani, Farbod, Weis, Tanja, Meder, Benjamin, Guan, Kaomei, Plass, Christoph, Weichenhan, Dieter, Siede, Dominik, Backs, Johannes
Publicado 2023

Identification of a DNA methylation signature to predict disease-free survival in locally advanced rectal cancer

por Gaedcke, Jochen, Leha, Andreas, Claus, Rainer, Weichenhan, Dieter, Jung, Klaus, Kitz, Julia, Grade, Marian, Wolff, Hendrik A., Jo, Peter, Doyen, Jérôme, Gérard, Jean-Pierre, Johnsen, Steven A., Plass, Christoph, Beißbarth, Tim, Ghadimi, Michael
Publicado 2014

Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma

por Goeppert, Benjamin, Toth, Reka, Singer, Stephan, Albrecht, Thomas, Lipka, Daniel B., Lutsik, Pavlo, Brocks, David, Baehr, Marion, Muecke, Oliver, Assenov, Yassen, Gu, Lei, Endris, Volker, Stenzinger, Albrecht, Mehrabi, Arianeb, Schirmacher, Peter, Plass, Christoph, Weichenhan, Dieter, Roessler, Stephanie
Publicado 2019

Genome-wide DNA methylation landscape defines specialization of regulatory T cells in tissues

por Delacher, Michael, Imbusch, Charles D., Weichenhan, Dieter, Breiling, Achim, Hotz-Wagenblatt, Agnes, Träger, Ulrike, Hofer, Ann-Cathrin, Kägebein, Danny, Wang, Qi, Frauhammer, Felix, Mallm, Jan-Philipp, Bauer, Katharina, Herrmann, Carl, Lang, Philipp, Brors, Benedikt, Plass, Christoph, Feuerer, Markus
Publicado 2017

ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition

por Bakr, Ali, Hey, Joschka, Sigismondo, Gianluca, Liu, Chun-Shan, Sadik, Ahmed, Goyal, Ashish, Cross, Alice, Iyer, Ramya Lakshmana, Müller, Patrick, Trauernicht, Max, Breuer, Kersten, Lutsik, Pavlo, Opitz, Christiane A, Krijgsveld, Jeroen, Weichenhan, Dieter, Plass, Christoph, Popanda, Odilia, Schmezer, Peter
Publicado 2021

TAL1 activation in T-cell acute lymphoblastic leukemia: a novel oncogenic 3’ neo-enhancer

por Smith, Charlotte, Goyal, Ashish, Weichenhan, Dieter, Allemand, Eric, Mayakonda, Anand, Toprak, Umut, Riedel, Anna, Balducci, Estelle, Manojkumar, Manisha, Pejkovska, Anastasija, Mücke, Oliver, Sollier, Etienne, Bakr, Ali, Breuer, Kersten, Lutsik, Pavlo, Hermine, Olivier, Spicuglia, Salvatore, Asnafi, Vahid, Plass, Christoph, Touzart, Aurore
Publicado 2023

Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo

por Gilsbach, Ralf, Schwaderer, Martin, Preissl, Sebastian, Grüning, Björn A., Kranzhöfer, David, Schneider, Pedro, Nührenberg, Thomas G., Mulero-Navarro, Sonia, Weichenhan, Dieter, Braun, Christian, Dreßen, Martina, Jacobs, Adam R., Lahm, Harald, Doenst, Torsten, Backofen, Rolf, Krane, Markus, Gelb, Bruce D., Hein, Lutz
Publicado 2018