OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3

por Herhaus, Lina, Al-Salihi, Mazin, Macartney, Thomas, Weidlich, Simone, Sapkota, Gopal P.
Publicado 2013

HIF1α-dependent mitophagy facilitates cardiomyoblast differentiation

por Zhao, Jin-Feng, Rodger, Catherine E., Allen, George F. G., Weidlich, Simone, Ganley, Ian G.
Publicado 2020

CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription

por Aregger, Michael, Kaskar, Aneesa, Varshney, Dhaval, Fernandez-Sanchez, Maria Elena, Inesta-Vaquera, Francisco A., Weidlich, Simone, Cowling, Victoria H.
Publicado 2016

DHX15 regulates CMTR1-dependent gene expression and cell proliferation

por Inesta-Vaquera, Francisco, Chaugule, Viduth K, Galloway, Alison, Chandler, Laurel, Rojas-Fernandez, Alejandro, Weidlich, Simone, Peggie, Mark, Cowling, Victoria H
Publicado 2018

MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes

por Abdul Rehman, Syed Arif, Kristariyanto, Yosua Adi, Choi, Soo-Youn, Nkosi, Pedro Junior, Weidlich, Simone, Labib, Karim, Hofmann, Kay, Kulathu, Yogesh
Publicado 2016

Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM

por Varshney, Dhaval, Petit, Alain-Pierre, Bueren-Calabuig, Juan A., Jansen, Chimed, Fletcher, Dan A., Peggie, Mark, Weidlich, Simone, Scullion, Paul, Pisliakov, Andrei V., Cowling, Victoria H.
Publicado 2016

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

por Kwasna, Dominika, Abdul Rehman, Syed Arif, Natarajan, Jayaprakash, Matthews, Stephen, Madden, Ross, De Cesare, Virginia, Weidlich, Simone, Virdee, Satpal, Ahel, Ivan, Gibbs-Seymour, Ian, Kulathu, Yogesh
Publicado 2018

USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling

por Herhaus, Lina, Al-Salihi, Mazin A., Dingwell, Kevin S., Cummins, Timothy D., Wasmus, Lize, Vogt, Janis, Ewan, Richard, Bruce, David, Macartney, Thomas, Weidlich, Simone, Smith, James C., Sapkota, Gopal P.
Publicado 2014

Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms

por Malik, Asad U., Karapetsas, Athanasios, Nirujogi, Raja S., Mathea, Sebastian, Chatterjee, Deep, Pal, Prosenjit, Lis, Pawel, Taylor, Matthew, Purlyte, Elena, Gourlay, Robert, Dorward, Mark, Weidlich, Simone, Toth, Rachel, Polinski, Nicole K., Knapp, Stefan, Tonelli, Francesca, Alessi, Dario R.
Publicado 2021

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

por Cammareri, Patrizia, Rose, Aidan M., Vincent, David F., Wang, Jun, Nagano, Ai, Libertini, Silvana, Ridgway, Rachel A., Athineos, Dimitris, Coates, Philip J., McHugh, Angela, Pourreyron, Celine, Dayal, Jasbani H. S., Larsson, Jonas, Weidlich, Simone, Spender, Lindsay C., Sapkota, Gopal P., Purdie, Karin J., Proby, Charlotte M., Harwood, Catherine A., Leigh, Irene M., Clevers, Hans, Barker, Nick, Karlsson, Stefan, Pritchard, Catrin, Marais, Richard, Chelala, Claude, South, Andrew P., Sansom, Owen J., Inman, Gareth J.
Publicado 2016