Blocking Gi/o-Coupled Signaling Eradicates Cancer Stem Cells and Sensitizes Breast Tumors to HER2-Targeted Therapies to Inhibit Tumor Relapse

por Lyu, Cancan, Ye, Yuanchao, Weigel, Ronald J., Chen, Songhai
Publicado 2022

Targeting G(i/o) protein–coupled receptor signaling blocks HER2-induced breast cancer development and enhances HER2-targeted therapy

por Lyu, Cancan, Ye, Yuanchao, Lensing, Maddison M., Wagner, Kay-Uwe, Weigel, Ronald J., Chen, Songhai
Publicado 2021

Discovery of SMAD4 promoters, transcription factor binding sites and deletions in juvenile polyposis patients

por Calva, Daniel, Dahdaleh, Fadi S., Woodfield, George, Weigel, Ronald J., Carr, Jennifer C., Chinnathambi, Sathivel, Howe, James R.
Publicado 2011

Human Melanoma Cells Over-Express Extracellular Matrix 1 (ECM1) Which Is Regulated by TFAP2C

por Lal, Geeta, Contreras, Piedad Gomez, Kulak, Mikhail, Woodfield, George, Bair, Thomas, Domann, Frederick E., Weigel, Ronald J.
Publicado 2013

Timing of Esophagectomy after Neoadjuvant Chemoradiation Therapy Affects the Incidence of Anastomotic Leaks

por Roh, Simon, Iannettoni, Mark D., Keech, John, Arshava, Evgeny V., Swatek, Anthony, Zimmerman, Miriam B., Weigel, Ronald J., Parekh, Kalpaj R.
Publicado 2019

Transcriptional Regulation of the GPX1 Gene by TFAP2C and Aberrant CpG Methylation in Human Breast Cancer

por Kulak, Mikhail V., Cyr, Anthony R., Woodfield, George W., Bogachek, Maria, Spanheimer, Philip M., Li, Tiandao, Price, David H., Domann, Frederick E., Weigel, Ronald J.
Publicado 2012

Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas

por Bogachek, Maria V., Park, Jung M., De Andrade, James P., Lorenzen, Allison W., Kulak, Mikhail V., White, Jeffrey R., Gu, Vivian W., Wu, Vincent T., Weigel, Ronald J.
Publicado 2016

Targeting the SUMO pathway as a novel treatment for anaplastic thyroid cancer

por De Andrade, James P., Lorenzen, Allison W., Wu, Vincent T., Bogachek, Maria V., Park, Jung M., Gu, Vivian W., Sevenich, Claire M., Cassady, Victoria C., Beck, Anna C., Kulak, Mikhail V., Robinson, Robert A., Lal, Geeta, Weigel, Ronald J.
Publicado 2017

AP-2γ Is Required for Maintenance of Multipotent Mammary Stem Cells

por Gu, Vivian W., Cho, Edward, Thompson, Dakota T., Cassady, Victoria C., Borcherding, Nicholas, Koch, Kelsey E., Wu, Vincent T., Lorenzen, Allison W., van der Heide, Dana M., White, Jeffrey R., Kulak, Mikhail V., Williams, Trevor, Zhang, Weizhou, Weigel, Ronald J.
Publicado 2020

TFAP2C Governs the Luminal Epithelial Phenotype in Mammary Development and Carcinogenesis

por Cyr, Anthony R, Kulak, Mikhail V., Park, Jung M., Bogachek, Maria V., Spanheimer, Philip M., Woodfield, George W., White-Baer, Lola S., O’Malley, Yunxia Q., Sugg, Sonia L., Olivier, Alicia K., Zhang, Weizhou, Domann, Frederick E., Weigel, Ronald J.
Publicado 2014

Cancer cell-intrinsic function of CD177 in attenuating β-Catenin signaling

por Kluz, Paige N., Kolb, Ryan, Xie, Qing, Borcherding, Nicholas, Liu, Qi, Luo, Yuewan, Kim, Myung-Chul, Wang, Linna, Zhang, Yinan, Li, Wei, Stipp, Christopher, Gibson-Corley, Katherine N., Zhao, Chen, Qi, Hank Heng, Bellizzi, Andrew, Tao, Andy W., Sugg, Sonia, Weigel, Ronald J., Zhou, Daohong, Shen, Xian, Zhang, Weizhou
Publicado 2020