Tumor Microenvironment of Hepatocellular Carcinoma: Challenges and Opportunities for New Treatment Options

por Sas, Zuzanna, Cendrowicz, Ewa, Weinhäuser, Isabel, Rygiel, Tomasz P.
Publicado 2022

P1345: EFFECT OF DECITABINE ON MACROPHAGE PHENOTYPE AND FUNCTION IN VITRO IN THE CONTEXT OF AML

por Hilberink, Jacobien, Weinhäuser, Isabel, Pereira-Martins, Diego, Jacob Schuringa, Jan, Huls, Gerwin
Publicado 2023

High ME1 Expression Is a Molecular Predictor of Post-Transplant Survival of Patients with Acute Myeloid Leukemia

por Ortiz Rojas, César Alexander, Costa-Neto, Abel, Pereira-Martins, Diego A., Le, Duy Minh, Sternadt, Dominique, Weinhäuser, Isabel, Huls, Gerwin, Schuringa, Jan Jacob, Magalhães Rego, Eduardo
Publicado 2022

PB1772: HIGH SLIT2 LEVELS ARE ASSOCIATED WITH GMP LIKE AML AND TREATMENT WITH RECOMBINANT SLIT2 INHIBITS LEUKEMOGENESIS

por Simoes, Luise Araujo de Albuquerque, Weinhäuser, Isabel, Pereira-Martins, Diego Antonio, Rojas, Cesar Alexander Ortiz, Pinheiro, Lucio Henrique, Bianco, Thiago Mantello, Cavaglieri, Rita de Cassia, Rego, Eduardo Magalhaes
Publicado 2023

Association of HMIP1 C-893A polymorphism and disease severity in patients with sickle cell anemia

por Pereira-Martins, Diego A., Domingos, Igor F., Belini-Junior, Edis, Coelho-Silva, Juan L., Weinhäuser, Isabel, Araújo, Aderson S., Lobo, Clarisse L., Bonini-Domingos, Claudia R., Bezerra, Marcos A., Lucena-Araujo, Antonio R.
Publicado 2021

Screening for myeloid mutations in patients with myelodysplastic syndromes and AML with myelodysplasia-related changes

por Bezerra, Matheus F., Larrazábal, Bruna R., Lima, Aleide S., Mello, Mariana R., Pimentel, Raphael F., Weinhäuser, Isabel, Costa, Fernando F., Fertrin, Kleber Y., Araújo, Aderson S., Machado, Cíntia G., Bezerra, Marcos A., Lucena-Araujo, Antonio R.
Publicado 2022

P466: THE INTRINSICALLY DISORDERED TRANSCRIPTIONAL REGULATOR MN1 DEPENDS ON THE CHAPERONE DNAJB6B FOR ITS FULL TRANSFORMING POTENTIAL

por Pereira-Martins, Diego A, van den Boom, Vincent, van Dijk, Noortje, Weinhauser, Isabel, Silveira, Douglas, M Bianco, Thiago, Alexander Ortiz Rojas, César, Huls, Gerwin, Quek, Lynn, R Lucena-Araujo, Antonio, Rego, Eduardo, Jacob Schuringa, Jan
Publicado 2023

The Expression of NTAL and Its Protein Interactors Is Associated With Clinical Outcomes in Acute Myeloid Leukemia

por Thomé, Carolina Hassibe, Ferreira, Germano Aguiar, Pereira-Martins, Diego Antonio, Augusto dos Santos, Guilherme, Almeida-Silveira, Douglas R., Weinhäuser, Isabel, Antônio de Souza, Gustavo, Houtsma, Roos, Schuringa, Jan Jacob, Rego, Eduardo M., Faça, Vitor M.
Publicado 2021

Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability

por Erdem, Ayşegül, Marin, Silvia, Pereira-Martins, Diego A., Geugien, Marjan, Cunningham, Alan, Pruis, Maurien G., Weinhäuser, Isabel, Gerding, Albert, Bakker, Barbara M., Wierenga, Albertus T. J., Rego, Eduardo M., Huls, Gerwin, Cascante, Marta, Schuringa, Jan Jacob
Publicado 2022

S127: DELTATP73 IMPOSES TP53 MUTANT-LIKE PHENOTYPES INCLUDING DRUG RESISTANCE AND POOR PROGNOSIS ON TP53-WILD TYPE ACUTE MYELOID LEUKEMIA.

por Pereira-Martins, Diego A, Alexander Ortiz Rojas, César, Weinhauser, Isabel, Silveira, Douglas, Wierenga, Albertus T J, van den Boom, Vincent, Bianco, Thiago M, Ammatuna, Emanuele, Quek, Lynn, Lucena-Araujo, Antonio R, Huls, Gerwin, Rego, Eduardo, Jacob Schuringa, Jan
Publicado 2023

MLL5 improves ATRA driven differentiation and promotes xenotransplant engraftment in acute promyelocytic leukemia model

por Pereira-Martins, Diego A., Weinhäuser, Isabel, Coelho-Silva, Juan Luiz, França-Neto, Pedro L., Almeida, Luciana Y., Bianco, Thiago M., Silva, Cleide L., França, Rafael F., Traina, Fabiola, Rego, Eduardo M., Schuringa, Jan Jacob, Lucena-Araujo, Antonio R.
Publicado 2021

The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy

por Lima, Keli, Pereira-Martins, Diego Antonio, de Miranda, Lívia Bassani Lins, Coelho-Silva, Juan Luiz, Leandro, Giovana da Silva, Weinhäuser, Isabel, Cavaglieri, Rita de Cássia, Leal, Aline de Medeiros, da Silva, Wellington Fernandes, Lange, Ana Paula Alencar de Lima, Velloso, Elvira Deolinda Rodrigues Pereira, Griessinger, Emmanuel, Hilberink, Jacobien R., Ammatuna, Emanuele, Huls, Gerwin, Schuringa, Jan Jacob, Rego, Eduardo Magalhães, Machado-Neto, João Agostinho
Publicado 2022

The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute Promyelocytic Leukemia Resistant Cells

por de Almeida, Luciana Yamamoto, Pereira-Martins, Diego A., Weinhäuser, Isabel, Ortiz, César, Cândido, Larissa A., Lange, Ana Paula, De Abreu, Nayara F., Mendonza, Sílvia E. S., de Deus Wagatsuma, Virgínia M., Do Nascimento, Mariane C., Paiva, Helder H., Alves-Paiva, Raquel M., Bonaldo, Camila C. O. M., Nascimento, Daniele C., Alves-Filho, José C., Scheucher, Priscila S., Lima, Ana Sílvia G., Schuringa, Jan Jacob, Ammantuna, Emanuele, Ottone, Tiziana, Noguera, Nelida I., Araujo, Cleide L., Rego, Eduardo M.
Publicado 2021

Reduced SLIT2 is Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in Acute Promyelocytic Leukemia

por Weinhäuser, Isabel, Pereira-Martins, Diego A., Ortiz, Cesar, Silveira, Douglas R., Simões, Luíse A. A., Bianco, Thiago M., Araujo, Cleide L., Koury, Luisa C., Melo, Raul A. M., Bittencourt, Rosane I., Pagnano, Katia, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro M., Gloria, Ana B., Kerbauy, Fábio, Chauffaille, Maria de Lourdes, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Ammatuna, Emanuele, Lucena-Araujo, Antonio R., Schuringa, Jan Jacob, Rego, Eduardo M.
Publicado 2020