Repair at Single Targeted DNA Double-Strand Breaks in Pluripotent and Differentiated Human Cells

por Fung, Hua, Weinstock, David M.
Publicado 2011

Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling

por Wachter, Franziska, Grunert, Michaela, Blaj, Cristina, Weinstock, David M, Jeremias, Irmela, Ehrhardt, Harald
Publicado 2013

Morphological alterations of the hypothalamus in idiopathic intracranial hypertension

por Kassubek, Rebecca, Weinstock, David, Behler, Anna, Müller, Hans-Peter, Dupuis, Luc, Kassubek, Jan, Ludolph, Albert C.
Publicado 2022

The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

por Xu, Ye, Sun, Yingli, Jiang, Xiaofeng, Ayrapetov, Marina K., Moskwa, Patryk, Yang, Shenghong, Weinstock, David M., Price, Brendan D.
Publicado 2010

HSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia

por Akahane, Koshi, Sanda, Takaomi, Mansour, Marc R., Radimerski, Thomas, DeAngelo, Daniel J., Weinstock, David M., Look, A. Thomas
Publicado 2015

Assessment of CD52 expression in "double-hit" and "double-expressor" lymphomas: Implications for clinical trial eligibility

por Craig, Jeffrey W., Mina, Michael J., Crombie, Jennifer L., LaCasce, Ann S., Weinstock, David M., Pinkus, Geraldine S., Pozdnyakova, Olga
Publicado 2018

Integrated multi-omics analyses reveal homology-directed repair pathway as a unique dependency in near-haploid leukemia

por Liu-Lupo, Yunpeng, Ham, James Dongjoo, Jeewajee, Swarna K. A., Nguyen, Lan, Delorey, Toni, Ramos, Azucena, Weinstock, David M., Regev, Aviv, Hemann, Michael T.
Publicado 2023

Identification of Circulating Serum Multi-MicroRNA Signatures in Human DLBCL Models

por Beheshti, Afshin, Stevenson, Kristen, Vanderburg, Charles, Ravi, Dashnamoorthy, McDonald, J. Tyson, Christie, Amanda L., Shigemori, Kay, Jester, Hallie, Weinstock, David M., Evens, Andrew M.
Publicado 2019

Next-Generation cDNA Screening for Oncogene and Resistance Phenotypes

por Shindoh, Nobuaki, Yoda, Akinori, Yoda, Yuka, Sullivan, Timothy J., Weigert, Oliver, Lane, Andrew A., Kopp, Nadja, Bird, Liat, Rodig, Scott J., Fox, Edward A., Weinstock, David M.
Publicado 2012

Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones

por Melchardt, Thomas, Hufnagl, Clemens, Weinstock, David M., Kopp, Nadja, Neureiter, Daniel, Tränkenschuh, Wolfgang, Hackl, Hubert, Weiss, Lukas, Rinnerthaler, Gabriel, Hartmann, Tanja N., Greil, Richard, Weigert, Oliver, Egle, Alexander
Publicado 2016

Deletion of ribosomal protein genes is a common vulnerability in human cancer, especially in concert with TP53 mutations

por Ajore, Ram, Raiser, David, McConkey, Marie, Jöud, Magnus, Boidol, Bernd, Mar, Brenton, Saksena, Gordon, Weinstock, David M, Armstrong, Scott, Ellis, Steven R, Ebert, Benjamin L, Nilsson, Björn
Publicado 2017

Leukemia circulation kinetics revealed through blood exchange method

por Miller, Alex B., Langenbucher, Adam, Rodriguez, Felicia H., Lin, Lin, Bray, Christina, Duquette, Sarah, Zhang, Ye, Goulet, Dan, Lane, Andrew A., Weinstock, David M., Hemann, Michael T., Manalis, Scott R.
Publicado 2023

TSLP signaling pathway map: a platform for analysis of TSLP-mediated signaling

por Zhong, Jun, Sharma, Jyoti, Raju, Rajesh, Palapetta, Shyam Mohan, Prasad, T. S. Keshava, Huang, Tai-Chung, Yoda, Akinori, Tyner, Jeffrey W., van Bodegom, Diederik, Weinstock, David M., Ziegler, Steven F., Pandey, Akhilesh
Publicado 2014

RAS-protein activation but not mutation status is an outcome predictor and unifying therapeutic target for high-risk acute lymphoblastic leukemia

por Koschut, David, Ray, Debleena, Li, Zhenhua, Giarin, Emanuela, Groet, Jürgen, Alić, Ivan, Kham, Shirley Kow-Yin, Chng, Wee Joo, Ariffin, Hany, Weinstock, David M., Yeoh, Allen Eng-Juh, Basso, Giuseppe, Nižetić, Dean
Publicado 2020

Tumor suppressor genes that escape from X-inactivation contribute to cancer sex bias

por Dunford, Andrew, Weinstock, David M., Savova, Virginia, Schumacher, Steven E., Cleary, John P., Yoda, Akinori, Sullivan, Timothy J., Hess, Julian M., Gimelbrant, Alexander A., Beroukhim, Rameen, Lawrence, Michael S., Getz, Gad, Lane, Andrew A.
Publicado 2016

DT2216—a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas

por He, Yonghan, Koch, Raphael, Budamagunta, Vivekananda, Zhang, Peiyi, Zhang, Xuan, Khan, Sajid, Thummuri, Dinesh, Ortiz, Yuma T., Zhang, Xin, Lv, Dongwen, Wiegand, Janet S., Li, Wen, Palmer, Adam C., Zheng, Guangrong, Weinstock, David M., Zhou, Daohong
Publicado 2020

PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA

por Day, Tovah A., Layer, Jacob V., Cleary, J. Patrick, Guha, Srijoy, Stevenson, Kristen E., Tivey, Trevor, Kim, Sunhee, Schinzel, Anna C., Izzo, Francesca, Doench, John, Root, David E., Hahn, William C., Price, Brendan D., Weinstock, David M.
Publicado 2017

Corrigendum: PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA

por Day, Tovah A., Layer, Jacob V., Cleary, J. Patrick, Guha, Srijoy, Stevenson, Kristen E., Tivey, Trevor, Kim, Sunhee, Schinzel, Anna C, Izzo, Francesca, Doench, John, Root, David E., Hahn, William C., Price, Brendan D., Weinstock, David M.
Publicado 2017

P1207: SERIAL SINGLE-CELL PROFILING OF MANTLE CELL LYMPHOMA REVEALS FUNCTIONAL AND MOLECULAR CORRELATES OF RESISTANCE TO BTK INHIBITOR-INCLUSIVE TRIPLET THERAPY

por Debaize, Lydie, Zhang, Ye, Ramseier, Michelle, Zhang, Mingzeng, Langenbucher, Adam, Winter, Peter S., Xu, Ran, Senhaji, Nezha, Redd, Robert A, Aryee, Martin J., Branch, Paul H., Kim, Austin I., Weinstock, David M., Shalek, Alex, Manalis, Scott R., Murakami, Mark A.
Publicado 2023

Characterization of midostaurin as a dual inhibitor of FLT3 and SYK and potentiation of FLT3 inhibition against FLT3-ITD-driven leukemia harboring activated SYK kinase

por Weisberg, Ellen L., Puissant, Alexandre, Stone, Richard, Sattler, Martin, Buhrlage, Sara J., Yang, Jing, Manley, Paul W., Meng, Chengcheng, Buonopane, Michael, Daley, John F., Lazo, Suzan, Wright, Renee, Weinstock, David M., Christie, Amanda L., Stegmaier, Kimberly, Griffin, James D.
Publicado 2017