The nucleotide addition cycle of RNA polymerase is controlled by two molecular hinges in the Bridge Helix domain

por Weinzierl, Robert OJ
Publicado 2010

The Bridge Helix of RNA Polymerase Acts as a Central Nanomechanical Switchboard for Coordinating Catalysis and Substrate Movement

por Weinzierl, Robert O. J.
Publicado 2012

Molecular Dynamics Simulations of Human FOXO3 Reveal Intrinsically Disordered Regions Spread Spatially by Intramolecular Electrostatic Repulsion

por Weinzierl, Robert O.J.
Publicado 2021

Molecular Dynamics of "Fuzzy" Transcriptional Activator-Coactivator Interactions

por Scholes, Natalie S., Weinzierl, Robert O. J.
Publicado 2016

Optimization of Molecular Dynamics Simulations of c-MYC(1-88)—An Intrinsically Disordered System

por Sullivan, Sandra S., Weinzierl, Robert O.J.
Publicado 2020

Transcribing Genes the Hard Way: In Vitro Reconstitution of Nanoarchaeal RNA Polymerase Reveals Unusual Active Site Properties

por Nottebaum, Sven, Weinzierl, Robert O. J.
Publicado 2021

The linker domain of basal transcription factor TFIIB controls distinct recruitment and transcription stimulation functions

por Wiesler, Simone C., Weinzierl, Robert O. J.
Publicado 2011

High-throughput Purification of Affinity-tagged Recombinant Proteins

por Wiesler, Simone C., Weinzierl, Robert O.J.
Publicado 2012

Multivalent and Bidirectional Binding of Transcriptional Transactivation Domains to the MED25 Coactivator

por Jeffery, Heather M., Weinzierl, Robert O. J.
Publicado 2020

Nucleotide Loading Modes of Human RNA Polymerase II as Deciphered by Molecular Simulations

por Génin, Nicolas E. J., Weinzierl, Robert O. J.
Publicado 2020

An aromatic residue switch in enhancer-dependent bacterial RNA polymerase controls transcription intermediate complex activity

por Wiesler, Simone C., Weinzierl, Robert O. J., Buck, Martin
Publicado 2013

Construction and functional analyses of a comprehensive σ(54) site-directed mutant library using alanine–cysteine mutagenesis

por Xiao, Yan, Wigneshweraraj, Siva R., Weinzierl, Robert, Wang, Yi-Ping, Buck, Martin
Publicado 2009

Bridge helix and trigger loop perturbations generate superactive RNA polymerases

por Tan, Lin, Wiesler, Simone, Trzaska, Dominika, Carney, Hannah C, Weinzierl, Robert OJ
Publicado 2008

The RNA polymerase factory: a robotic in vitro assembly platform for high-throughput production of recombinant protein complexes

por Nottebaum, Sven, Tan, Lin, Trzaska, Dominika, Carney, Hannah C., Weinzierl, Robert O. J.
Publicado 2008

Systematic mutational analysis of the LytTR DNA binding domain of Staphylococcus aureus virulence gene transcription factor AgrA

por Nicod, Sophie S., Weinzierl, Robert O. J., Burchell, Lynn, Escalera-Maurer, Andres, James, Ellen H., Wigneshweraraj, Sivaramesh
Publicado 2014

Activity Map of the Escherichia coli RNA Polymerase Bridge Helix

por Jovanovic, Milija, Burrows, Patricia C., Bose, Daniel, Cámara, Beatriz, Wiesler, Simone, Zhang, Xiaodong, Wigneshweraraj, Sivaramesh, Weinzierl, Robert O. J., Buck, Martin
Publicado 2011