Gene specific therapies – the next therapeutic milestone in neurology

por Brenner, David, Ludolph, Albert C., Weishaupt, Jochen H.
Publicado 2020

ALS-linked loss of Cyclin-F function affects HSP90

por Siebert, Alexander, Gattringer, Vanessa, Weishaupt, Jochen H, Behrends, Christian
Publicado 2022

Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis

por Freischmidt, Axel, Müller, Kathrin, Ludolph, Albert C, Weishaupt, Jochen H
Publicado 2013

Downstream Effects of Mutations in SOD1 and TARDBP Converge on Gene Expression Impairment in Patient-Derived Motor Neurons

por Dash, Banaja P., Freischmidt, Axel, Weishaupt, Jochen H., Hermann, Andreas
Publicado 2022

Cell-Penetrating Fragments of the Cdk5 Regulatory Subunit Are Protective in Models of Neurodegeneration

por Liman, Jan, Weishaupt, Jochen H., Bähr, Mathias, Dietz, Gunnar P.H.
Publicado 2010

Elevated mRNA-levels of distinct mitochondrial and plasma membrane Ca(2+) transporters in individual hypoglossal motor neurons of endstage SOD1 transgenic mice

por Mühling, Tobias, Duda, Johanna, Weishaupt, Jochen H., Ludolph, Albert C., Liss, Birgit
Publicado 2014

Commentary: Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity

por Freischmidt, Axel, Brenner, David, Ludolph, Albert C., Andersen, Peter M., Weishaupt, Jochen H.
Publicado 2020

Quadruple genetic variants in a sporadic ALS patient

por Yilmaz, Rüstem, Weishaupt, Kanchi, Valkadinov, Ivan, Knehr, Antje, Brenner, David, Weishaupt, Jochen H.
Publicado 2022

Current knowledge and recent insights into the genetic basis of amyotrophic lateral sclerosis

por Volk, Alexander E., Weishaupt, Jochen H., Andersen, Peter M., Ludolph, Albert C., Kubisch, Christian
Publicado 2018

Profilin 1 with the amyotrophic lateral sclerosis associated mutation T109M displays unaltered actin binding and does not affect the actin cytoskeleton

por Freischmidt, Axel, Schöpflin, Marcel, Feiler, Marisa S., Fleck, Ann-Katrin, Ludolph, Albert C., Weishaupt, Jochen H.
Publicado 2015

In vivo histopathological staging in C9orf72-associated ALS: A tract of interest DTI study

por Müller, Hans-Peter, Del Tredici, Kelly, Lulé, Dorothée, Müller, Kathrin, Weishaupt, Jochen H., Ludolph, Albert C., Kassubek, Jan
Publicado 2020

T-cell dysregulation is associated with disease severity in Parkinson’s Disease

por Bhatia, Divisha, Grozdanov, Veselin, Ruf, Wolfgang P., Kassubek, Jan, Ludolph, Albert C., Weishaupt, Jochen H., Danzer, Karin M.
Publicado 2021

Proteasome impairment by α-synuclein

por Zondler, Lisa, Kostka, Marcus, Garidel, Patrick, Heinzelmann, Udo, Hengerer, Bastian, Mayer, Benjamin, Weishaupt, Jochen H., Gillardon, Frank, Danzer, Karin M.
Publicado 2017

Low T-cell reactivity to TDP-43 peptides in ALS

por Ramachandran, Swetha, Grozdanov, Veselin, Leins, Bianca, Kandler, Katharina, Witzel, Simon, Mulaw, Medhanie, Ludolph, Albert C., Weishaupt, Jochen H., Danzer, Karin M.
Publicado 2023

Both systemic and local application of Granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy

por Frank, Tobias, Schlachetzki, Johannes CM, Göricke, Bettina, Meuer, Katrin, Rohde, Gundula, Dietz, Gunnar PH, Bähr, Mathias, Schneider, Armin, Weishaupt, Jochen H
Publicado 2009

Age Increases Monocyte Adhesion on Collagen

por Khalaji, Samira, Zondler, Lisa, KleinJan, Fenneke, Nolte, Ulla, Mulaw, Medhanie A., Danzer, Karin M., Weishaupt, Jochen H., Gottschalk, Kay-E.
Publicado 2017

Acute TBK1/IKK-ε Inhibition Enhances the Generation of Disease-Associated Microglia-Like Phenotype Upon Cortical Stab-Wound Injury

por Rehman, Rida, Tar, Lilla, Olamide, Adeyemi Jubril, Li, Zhenghui, Kassubek, Jan, Böckers, Tobias, Weishaupt, Jochen, Ludolph, Albert, Wiesner, Diana, Roselli, Francesco
Publicado 2021

FUS mutations dominate TBK1 mutations in FUS/TBK1 double-mutant ALS/FTD pedigrees

por Brenner, David, Müller, Kathrin, Lattante, Serena, Yilmaz, Rüstem, Knehr, Antje, Freischmidt, Axel, Ludolph, Albert C., Andersen, Peter M., Weishaupt, Jochen H.
Publicado 2021

Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson’s disease

por Tönges, Lars, Frank, Tobias, Tatenhorst, Lars, Saal, Kim A., Koch, Jan C., Szegő, Éva M., Bähr, Mathias, Weishaupt, Jochen H., Lingor, Paul
Publicado 2012

Stress induced TDP-43 mobility loss independent of stress granules

por Streit, Lisa, Kuhn, Timo, Vomhof, Thomas, Bopp, Verena, Ludolph, Albert C., Weishaupt, Jochen H., Gebhardt, J. Christof M., Michaelis, Jens, Danzer, Karin M.
Publicado 2022