Ubiquitylation in ERAD: Reversing to Go Forward?

por Tsai, Yien Che, Weissman, Allan M.
Publicado 2011

Novel Aspects of Degradation of T Cell Receptor Subunits from the Endoplasmic Reticulum (ER) in T Cells: Importance of Oligosaccharide Processing, Ubiquitination, and Proteasome-de...

por Yang, Mei, Omura, Satoshi, Bonifacino, Juan S., Weissman, Allan M.
Publicado 1998

Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import

por Plafker, Scott M., Plafker, Kendra S., Weissman, Allan M., Macara, Ian G.
Publicado 2004

Crystal structure of the Schizosaccharomyces pombe U7BR E2-binding region in complex with Ubc7

por Hann, Zachary S., Metzger, Meredith B., Weissman, Allan M., Lima, Christopher D.
Publicado 2019

The Ubiquitin Ligase (E3) Psh1p Is Required for Proper Segregation of both Centromeric and Two-Micron Plasmids in Saccharomyces cerevisiae

por Metzger, Meredith B., Scales, Jessica L., Dunklebarger, Mitchell F., Weissman, Allan M.
Publicado 2017

A protein quality control pathway at the mitochondrial outer membrane

por Metzger, Meredith B, Scales, Jessica L, Dunklebarger, Mitchell F, Loncarek, Jadranka, Weissman, Allan M
Publicado 2020

Ubiquitin Ligase gp78 Targets Unglycosylated Prion Protein PrP for Ubiquitylation and Degradation

por Shao, Jia, Choe, Vitnary, Cheng, Haili, Tsai, Yien Che, Weissman, Allan M., Luo, Shiwen, Rao, Hai
Publicado 2014

Differential sensitivity of the yeast Lon protease Pim1p to impaired mitochondrial respiration

por Metzger, Meredith B., Scales, Jessica L., Grant, Garis A., Molnar, Abigail E., Loncarek, Jadranka, Weissman, Allan M.
Publicado 2023

An ubiquitin-dependent balance between mitofusin turnover and fatty acids desaturation regulates mitochondrial fusion

por Cavellini, Laetitia, Meurisse, Julie, Findinier, Justin, Erpapazoglou, Zoi, Belgareh-Touzé, Naïma, Weissman, Allan M., Cohen, Mickael M.
Publicado 2017

Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond

por Zhao, Bo, Tsai, Yien Che, Jin, Bo, Wang, Bufan, Wang, Yiyang, Zhou, Han, Carpenter, Tomaya, Weissman, Allan M., Yin, Jun
Publicado 2020

Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system

por Tsai, Yien Che, Leichner, Gil S., Pearce, Margaret M. P., Wilson, Gaye Lynn, Wojcikiewicz, Richard J. H., Roitelman, Joseph, Weissman, Allan M.
Publicado 2012

SARS-CoV-2 papain-like protease plays multiple roles in regulating cellular proteins in the endoplasmic reticulum

por Yang, Mei, Mariano, Jennifer, Su, Rebecca, Smith, Christopher E., Das, Sudipto, Gill, Catherine, Andresson, Thorkell, Loncarek, Jadranka, Tsai, Yien Che, Weissman, Allan M.
Publicado 2023

Activation of the unfolded protein response in sarcoma cells treated with rapamycin or temsirolimus

por Briggs, Joseph W., Ren, Ling, Chakrabarti, Kristi R., Tsai, Yien Che, Weissman, Allan M., Hansen, Ryan J., Gustafson, Daniel L., Khan, Yousuf A., Dinman, Jonathan D., Khanna, Chand
Publicado 2017

Differences in the Tumor Microenvironment between African-American and European-American Breast Cancer Patients

por Martin, Damali N., Boersma, Brenda J., Yi, Ming, Reimers, Mark, Howe, Tiffany M., Yfantis, Harry G., Tsai, Yien Che, Williams, Erica H., Lee, Dong H., Stephens, Robert M., Weissman, Allan M., Ambs, Stefan
Publicado 2009

Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain

por Magnussen, Helge M., Ahmed, Syed F., Sibbet, Gary. J., Hristova, Ventzislava A., Nomura, Koji, Hock, Andreas K., Archibald, Lewis J., Jamieson, Andrew G., Fushman, David, Vousden, Karen H., Weissman, Allan M., Huang, Danny T.
Publicado 2020

A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation

por Smith, Christopher E., Tsai, Yien Che, Liang, Yu-He, Khago, Domarin, Mariano, Jennifer, Li, Jess, Tarasov, Sergey G., Gergel, Emma, Tsai, Borong, Villaneuva, Matthew, Clapp, Michelle E., Magidson, Valentin, Chari, Raj, Byrd, R. Andrew, Ji, Xinhua, Weissman, Allan M.
Publicado 2021

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule The...

por Chung, W. Joon, Goeckeler-Fried, Jennifer L., Havasi, Viktoria, Chiang, Annette, Rowe, Steven M., Plyler, Zackery E., Hong, Jeong S., Mazur, Marina, Piazza, Gary A., Keeton, Adam B., White, E. Lucile, Rasmussen, Lynn, Weissman, Allan M., Denny, R. Aldrin, Brodsky, Jeffrey L., Sorscher, Eric J.
Publicado 2016

Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis

por Marie, Kerrie L., Sassano, Antonella, Yang, Howard H., Michalowski, Aleksandra M., Michael, Helen T., Guo, Theresa, Tsai, Yien Che, Weissman, Allan M., Lee, Maxwell P., Jenkins, Lisa M., Zaidi, M. Raza, Pérez-Guijarro, Eva, Day, Chi-Ping, Ylaya, Kris, Hewitt, Stephen M., Patel, Nimit L., Arnheiter, Heinz, Davis, Sean, Meltzer, Paul S., Merlino, Glenn, Mishra, Pravin J.
Publicado 2020

Protein expression of the gp78 E3 ligase predicts poor breast cancer outcome based on race

por Singhal, Sandeep K., Byun, Jung S., Yan, Tingfen, Yancey, Ryan, Caban, Ambar, Gil Hernandez, Sara, Bufford, Sediqua, Hewitt, Stephen M., Winfield, Joy, Pradhan, Jaya, Mustkov, Vesco, McDonald, Jasmine A., Pérez-Stable, Eliseo J., Nápoles, Anna María, Vohra, Nasreen, De Siervi, Adriana, Yates, Clayton, Davis, Melissa B., Yang, Mei, Tsai, Yien Che, Weissman, Allan M., Gardner, Kevin
Publicado 2022