BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression

por Cohen, Stephanie M., Chastain, Paul D., Rosson, Gary B., Groh, Beezly S., Weissman, Bernard E., Kaufman, David G., Bultman, Scott J.
Publicado 2010

The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells

por Gao, Yanzhe, Kardos, Jordan, Yang, Yang, Tamir, Tigist Y., Mutter-Rottmayer, Elizabeth, Weissman, Bernard, Major, Michael B., Kim, William Y., Vaziri, Cyrus
Publicado 2018

Small molecule screen identifies pyrimethamine as an inhibitor of NRF2-driven esophageal hyperplasia

por Paiboonrungruang, Chorlada, Xiong, Zhaohui, Lamson, David, Li, Yahui, Bowman, Brittany, Chembo, Julius, Huang, Caizhi, Li, Jianying, Livingston, Eric W., Frank, Jon E., Chen, Vivian, Li, Yong, Weissman, Bernard, Yuan, Hong, Williams, Kevin P., Ben Major, M., Chen, Xiaoxin
Publicado 2023

The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer

por Soldi, Raffaella, Ghosh Halder, Tithi, Weston, Alexis, Thode, Trason, Drenner, Kevin, Lewis, Rhonda, Kaadige, Mohan R., Srivastava, Shreyesi, Daniel Ampanattu, Sherin, Rodriguez del Villar, Ryan, Lang, Jessica, Vankayalapati, Hariprasad, Weissman, Bernard, Trent, Jeffrey M., Hendricks, William P. D., Sharma, Sunil
Publicado 2020

Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target

por Weingart, Melanie F., Roth, Jacquelyn J., Hutt-Cabezas, Marianne, Busse, Tracy M., Kaur, Harpreet, Price, Antoinette, Maynard, Rachael, Rubens, Jeffrey, Taylor, Isabella, Mao, Xing-gang, Xu, Jingying, Kuwahara, Yasumichi, Allen, Sariah J., Erdreich-Epstein, Anat, Weissman, Bernard E., Orr, Brent A., Eberhart, Charles G., Biegel, Jaclyn A., Raabe, Eric H.
Publicado 2014

Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type

por Karnezis, Anthony N, Wang, Yemin, Ramos, Pilar, Hendricks, William PD, Oliva, Esther, D'Angelo, Emanuela, Prat, Jaime, Nucci, Marisa R, Nielsen, Torsten O, Chow, Christine, Leung, Samuel, Kommoss, Friedrich, Kommoss, Stefan, Silva, Annacarolina, Ronnett, Brigitte M, Rabban, Joseph T, Bowtell, David D, Weissman, Bernard E, Trent, Jeffrey M, Gilks, C Blake, Huntsman, David G
Publicado 2015

Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism

por Orlando, Krystal Ann, Douglas, Amber K, Abudu, Aierken, Wang, Yemin, Tessier-Cloutier, Basile, Su, Weiping, Peters, Alec, Sherman, Larry S, Moore, Rayvon, Nguyen, Vinh, Negri, Gian Luca, Colborne, Shane, Morin, Gregg B, Kommoss, Friedrich, Lang, Jessica D, Hendricks, William PD, Raupach, Elizabeth A, Pirrotte, Patrick, Huntsman, David G, Trent, Jeffrey M, Parker, Joel S, Raab, Jesse R, Weissman, Bernard E
Publicado 2020

Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss

por Zhu, Xianbing, Fu, Zheng, Chen, Shary Y., Ong, Dionzie, Aceto, Giulio, Ho, Rebecca, Steinberger, Jutta, Monast, Anie, Pilon, Virginie, Li, Eunice, Ta, Monica, Ching, Kyle, Adams, Bianca N., Negri, Gian L., Choiniere, Luc, Fu, Lili, Pavlakis, Kitty, Pirrotte, Patrick, Avizonis, Daina Z., Trent, Jeffrey, Weissman, Bernard E., Klein Geltink, Ramon I., Morin, Gregg B., Park, Morag, Huntsman, David G., Foulkes, William D., Wang, Yemin, Huang, Sidong
Publicado 2023