Translational repression protects human keratinocytes from UVB-induced apoptosis through a discordant eIF2 kinase stress response

por Collier, Ann E., Wek, Ronald C., Spandau, Dan F
Publicado 2015

Translational control of a human CDKN1A mRNA splice variant regulates the fate of UVB-irradiated human keratinocytes

por Collier, Ann E., Spandau, Dan F., Wek, Ronald C.
Publicado 2018

An RNA stem-loop functions in conjunction with an upstream open reading frame to direct preferential translation in the integrated stress response

por Amin, Parth H., Carlson, Kenneth R., Wek, Ronald C.
Publicado 2022

Selective control of amino acid metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiae

por Zaborske, John M, Wu, Xiaochen, Wek, Ronald C, Pan, Tao
Publicado 2010

Simultaneous Ribosome Profiling of Human Host Cells Infected with Toxoplasma gondii

por Holmes, Michael J., Shah, Premal, Wek, Ronald C., Sullivan, William J.
Publicado 2019

Regulation of arginine transport by GCN2 eIF2 kinase is important for replication of the intracellular parasite Toxoplasma gondii

por Augusto, Leonardo, Amin, Parth H., Wek, Ronald C., Sullivan, William J.
Publicado 2019

Activation and execution of the hepatic integrated stress response by dietary essential amino acid deprivation is amino acid specific

por Jonsson, William O., Mirek, Emily T., Wek, Ronald C., Anthony, Tracy G.
Publicado 2022

Guanabenz Reverses a Key Behavioral Change Caused by Latent Toxoplasmosis in Mice by Reducing Neuroinflammation

por Martynowicz, Jennifer, Augusto, Leonardo, Wek, Ronald C., Boehm, Stephen L., Sullivan, William J.
Publicado 2019

Activation of Gcn2 by small molecules designed to be inhibitors

por Carlson, Kenneth R., Georgiadis, Millie M., Tameire, Feven, Staschke, Kirk A., Wek, Ronald C.
Publicado 2023

mRNA cap-binding protein eIF4E1 is a novel regulator of Toxoplasma gondii latency

por Holmes, Michael J., Bastos, Matheus S., Dey, Vishakha, Severo, Vanessa, Wek, Ronald C., Sullivan, William J.
Publicado 2023

CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis

por Willy, Jeffrey A., Young, Sara K., Stevens, James L., Masuoka, Howard C., Wek, Ronald C.
Publicado 2015

TgIF2K-B Is an eIF2α Kinase in Toxoplasma gondii That Responds to Oxidative Stress and Optimizes Pathogenicity

por Augusto, Leonardo, Martynowicz, Jennifer, Amin, Parth H., Carlson, Kenneth R., Wek, Ronald C., Sullivan, William J.
Publicado 2021

Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4

por Ogbechi, Joy, Hall, Belinda S., Sbarrato, Thomas, Taunton, Jack, Willis, Anne E., Wek, Ronald C., Simmonds, Rachel E.
Publicado 2018

Toxoplasma gondii Co-opts the Unfolded Protein Response To Enhance Migration and Dissemination of Infected Host Cells

por Augusto, Leonardo, Martynowicz, Jennifer, Amin, Parth H., Alakhras, Nada S., Kaplan, Mark H., Wek, Ronald C., Sullivan, William J.
Publicado 2020

Disease-associated mutations in a bifunctional aminoacyl-tRNA synthetase gene elicit the integrated stress response

por Jin, Danni, Wek, Sheree A., Kudlapur, Nathan T., Cantara, William A., Bakhtina, Marina, Wek, Ronald C., Musier-Forsyth, Karin
Publicado 2021

Aminoacylation‐defective bi‐allelic mutations in human EPRS1 associated with psychomotor developmental delay, epilepsy, and deafness

por Jin, Danni, Wek, Sheree A., Cordova, Ricardo A., Wek, Ronald C., Lacombe, Didier, Michaud, Vincent, Musier‐Forsyth, Karin
Publicado 2022

Different Effect of Proteasome Inhibition on Vesicular Stomatitis Virus and Poliovirus Replication

por Neznanov, Nickolay, Dragunsky, Eugenia M., Chumakov, Konstantin M., Neznanova, Lubov, Wek, Ronald C., Gudkov, Andrei V., Banerjee, Amiya K.
Publicado 2008

CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis

por Teske, Brian F., Fusakio, Michael E., Zhou, Donghui, Shan, Jixiu, McClintick, Jeanette N., Kilberg, Michael S., Wek, Ronald C.
Publicado 2013

Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential

por Kwon, Jason J., Willy, Jeffrey A., Quirin, Kayla A., Wek, Ronald C., Korc, Murray, Yin, Xiao-Ming, Kota, Janaiah
Publicado 2016

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress

por Teske, Brian F., Wek, Sheree A., Bunpo, Piyawan, Cundiff, Judy K., McClintick, Jeanette N., Anthony, Tracy G., Wek, Ronald C.
Publicado 2011