On the Origin of Large Flexibility of P-glycoprotein in the Inward-facing State

por Wen, Po-Chao, Verhalen, Brandy, Wilkens, Stephan, Mchaourab, Hassane S., Tajkhorshid, Emad
Publicado 2013

Probing key elements of teixobactin–lipid II interactions in membranes

por Wen, Po-Chao, Vanegas, Juan M., Rempe, Susan B., Tajkhorshid, Emad
Publicado 2018

Visualizing Functional Motions of Membrane Transporters with Molecular Dynamics Simulations

por Shaikh, Saher A., Li, Jing, Enkavi, Giray, Wen, Po-Chao, Huang, Zhijian, Tajkhorshid, Emad
Publicado 2013

Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

por Mishra, Smriti, Verhalen, Brandy, Stein, Richard A, Wen, Po-Chao, Tajkhorshid, Emad, Mchaourab, Hassane S
Publicado 2014

Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target

por Camara, Amadou K. S., Zhou, YiFan, Wen, Po-Chao, Tajkhorshid, Emad, Kwok, Wai-Meng
Publicado 2017

Conformational Dynamics at the Inner Gate of KcsA during Activation

por Hulse, Raymond E., Sachleben, Joseph R., Wen, Po-Chao, Moradi, Mahmoud, Tajkhorshid, Emad, Perozo, Eduardo
Publicado 2014

Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2

por Rasouli, Ali, Yu, Qin, Dehghani-Ghahnaviyeh, Sepehr, Wen, Po-Chao, Kowal, Julia, Locher, Kaspar P., Tajkhorshid, Emad
Publicado 2022

Structural basis of complex formation between mitochondrial anion channel VDAC1 and Hexokinase-II

por Haloi, Nandan, Wen, Po-Chao, Cheng, Qunli, Yang, Meiying, Natarajan, Gayathri, Camara, Amadou K. S., Kwok, Wai-Meng, Tajkhorshid, Emad
Publicado 2021

Rationalizing the generation of broad spectrum antibiotics with the addition of a positive charge

por Haloi, Nandan, Vasan, Archit Kumar, Geddes, Emily J., Prasanna, Arjun, Wen, Po-Chao, Metcalf, William W., Hergenrother, Paul J., Tajkhorshid, Emad
Publicado 2021

Role of internal loop dynamics in antibiotic permeability of outer membrane porins

por Vasan, Archit Kumar, Haloi, Nandan, Ulrich, Rebecca Joy, Metcalf, Mary Elizabeth, Wen, Po-Chao, Metcalf, William W., Hergenrother, Paul J., Shukla, Diwakar, Tajkhorshid, Emad
Publicado 2022

Structural and functional diversity calls for a new classification of ABC transporters

por Thomas, Christoph, Aller, Stephen G., Beis, Konstantinos, Carpenter, Elisabeth P., Chang, Geoffrey, Chen, Lei, Dassa, Elie, Dean, Michael, Van Hoa, Franck Duong, Ekiert, Damian, Ford, Robert, Gaudet, Rachelle, Gong, Xin, Holland, I. Barry, Huang, Yihua, Kahne, Daniel K., Kato, Hiroaki, Koronakis, Vassilis, Koth, Christopher M., Lee, Youngsook, Lewinson, Oded, Lill, Roland, Martinoia, Enrico, Murakami, Satoshi, Pinkett, Heather W., Poolman, Bert, Rosenbaum, Daniel, Sarkadi, Balazs, Schmitt, Lutz, Schneider, Erwin, Shi, Yigong, Shyng, Show-Ling, Slotboom, Dirk J., Tajkhorshid, Emad, Tieleman, D. Peter, Ueda, Kazumitsu, Váradi, András, Wen, Po-Chao, Yan, Nieng, Zhang, Peng, Zheng, Hongjin, Zimmer, Jochen, Tampé, Robert
Publicado 2020