Prion strains viewed through the lens of cryo-EM

por Manka, Szymon W., Wenborn, Adam, Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2022

Sex Effects in Mouse Prion Disease Incubation Time

por Akhtar, Shaheen, Wenborn, Adam, Brandner, Sebastian, Collinge, John, Lloyd, Sarah E.
Publicado 2011

Isolation of Proteinase K-Sensitive Prions Using Pronase E and Phosphotungstic Acid

por D'Castro, Laura, Wenborn, Adam, Gros, Nathalie, Joiner, Susan, Cronier, Sabrina, Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2010

A structural basis for prion strain diversity

por Manka, Szymon W., Wenborn, Adam, Betts, Jemma, Joiner, Susan, Saibil, Helen R., Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2023

Sod1 Deficiency Reduces Incubation Time in Mouse Models of Prion Disease

por Akhtar, Shaheen, Grizenkova, Julia, Wenborn, Adam, Hummerich, Holger, Fernandez de Marco, Mar, Brandner, Sebastian, Collinge, John, Lloyd, Sarah E.
Publicado 2013

2.7 Å cryo-EM structure of ex vivo RML prion fibrils

por Manka, Szymon W., Zhang, Wenjuan, Wenborn, Adam, Betts, Jemma, Joiner, Susan, Saibil, Helen R., Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2022

Structural features distinguishing infectious ex vivo mammalian prions from non-infectious fibrillar assemblies generated in vitro

por Terry, Cassandra, Harniman, Robert L., Sells, Jessica, Wenborn, Adam, Joiner, Susan, Saibil, Helen R., Miles, Mervyn J., Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2019

A novel and rapid method for obtaining high titre intact prion strains from mammalian brain

por Wenborn, Adam, Terry, Cassandra, Gros, Nathalie, Joiner, Susan, D’Castro, Laura, Panico, Silvia, Sells, Jessica, Cronier, Sabrina, Linehan, Jacqueline M., Brandner, Sebastian, Saibil, Helen R., Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2015

Ex vivo mammalian prions are formed of paired double helical prion protein fibrils

por Terry, Cassandra, Wenborn, Adam, Gros, Nathalie, Sells, Jessica, Joiner, Susan, Hosszu, Laszlo L. P., Tattum, M. Howard, Panico, Silvia, Clare, Daniel K., Collinge, John, Saibil, Helen R., Wadsworth, Jonathan D. F.
Publicado 2016

Highly infectious prions are not directly neurotoxic

por Benilova, Iryna, Reilly, Madeleine, Terry, Cassandra, Wenborn, Adam, Schmidt, Christian, Marinho, Aline T., Risse, Emmanuel, Al-Doujaily, Huda, Wiggins De Oliveira, Michael, Sandberg, Malin K., Wadsworth, Jonathan D. F., Jat, Parmjit S., Collinge, John
Publicado 2020