Tetracycline-Inactivating Enzymes

por Markley, Jana L., Wencewicz, Timothy A.
Publicado 2018

Emergence of Ferrichelatase Activity in a Siderophore-Binding Protein Supports an Iron Shuttle in Bacteria

por Endicott, Nathaniel P., Rivera, Gerry Sann M., Yang, Jinping, Wencewicz, Timothy A.
Publicado 2020

The structural basis of N-acyl-α-amino-β-lactone formation catalyzed by a nonribosomal peptide synthetase

por Kreitler, Dale F., Gemmell, Erin M., Schaffer, Jason E., Wencewicz, Timothy A., Gulick, Andrew M.
Publicado 2019

Evidence that 2-hydroxyglutarate is not readily metabolized in colorectal carcinoma cells

por Gelman, Susan J., Mahieu, Nathaniel G., Cho, Kevin, Llufrio, Elizabeth M., Wencewicz, Timothy A., Patti, Gary J.
Publicado 2015

Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases

por Kumar, Hirdesh, Williford, Emily E., Blake, Kevin S., Virgin-Downey, Brett, Dantas, Gautam, Wencewicz, Timothy A., Tolia, Niraj H.
Publicado 2023

Publisher Correction: Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases

por Kumar, Hirdesh, Williford, Emily E., Blake, Kevin S., Virgin-Downey, Brett, Dantas, Gautam, Wencewicz, Timothy A., Tolia, Niraj H.
Publicado 2023

Structural and Biochemical Characterization of the Flavin-Dependent Siderophore-Interacting Protein from Acinetobacter baumannii

por Valentino, Hannah, Korasick, David A., Bohac, Tabbetha J., Shapiro, Justin A., Wencewicz, Timothy A., Tanner, John J., Sobrado, Pablo
Publicado 2021

An acyl-adenylate mimic reveals the structural basis for substrate recognition by the iterative siderophore synthetase DesD

por Yang, Jinping, Banas, Victoria S., Patel, Ketan D., Rivera, Gerry S.M., Mydy, Lisa S., Gulick, Andrew M., Wencewicz, Timothy A.
Publicado 2022

Plasticity, dynamics, and inhibition of emerging tetracycline-resistance enzymes

por Park, Jooyoung, Gasparrini, Andrew J., Reck, Margaret R., Symister, Chanez T., Elliott, Jennifer L., Vogel, Joseph P., Wencewicz, Timothy A., Dantas, Gautam, Tolia, Niraj H.
Publicado 2017

Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance

por Gasparrini, Andrew J., Markley, Jana L., Kumar, Hirdesh, Wang, Bin, Fang, Luting, Irum, Sidra, Symister, Chanez T., Wallace, Meghan, Burnham, Carey-Ann D., Andleeb, Saadia, Tolia, Niraj H., Wencewicz, Timothy A., Dantas, Gautam
Publicado 2020