Improved Protein Kinase C Affinity through Final Step Diversification of a Simplified Salicylate-Derived Bryostatin Analog Scaffold

por Wender, Paul A., Staveness, Daryl
Publicado 2014

Tetramethyleneethane Equivalents: Recursive Reagents for Serialized Cycloadditions

por Wender, Paul A., Jeffreys, Matthew S., Raub, Andrew G.
Publicado 2015

Molecular dynamics simulations reveal ligand-controlled positioning of a peripheral protein complex in membranes

por Ryckbosch, Steven M., Wender, Paul A., Pande, Vijay S.
Publicado 2017

Function through Synthesis-Informed Design

por Wender, Paul A., Quiroz, Ryan V., Stevens, Matthew C.
Publicado 2015

Propargyltrimethylsilanes as Allene Equivalents in Transition Metal-Catalyzed [5 + 2] Cycloadditions

por Wender, Paul A., Inagaki, Fuyuhiko, Pfaffenbach, Magnus, Stevens, Matthew C.
Publicado 2014

Computer-Guided Design, Synthesis, and Protein Kinase C Affinity of a New Salicylate-Based Class of Bryostatin Analogs

por Wender, Paul A., Nakagawa, Yu, Near, Katherine E., Staveness, Daryl
Publicado 2014

Bioorthogonal Catalysis: A General Method To Evaluate Metal-Catalyzed Reactions in Real Time in Living Systems Using a Cellular Luciferase Reporter System

por Hsu, Hsiao-Tieh, Trantow, Brian M., Waymouth, Robert M., Wender, Paul A.
Publicado 2015

“Picolog,” a Synthetically-Available Bryostatin Analog, Inhibits Growth of MYC-Induced Lymphoma In Vivo

por DeChristopher, Brian A., Fan, Alice C., Felsher, Dean W., Wender, Paul A.
Publicado 2012

Cell-Penetrating, Guanidinium-Rich Molecular Transporters for Overcoming Efflux-Mediated Multidrug Resistance

por Vargas, Jessica R., Stanzl, Erika Geihe, Teng, Nelson N. H., Wender, Paul A.
Publicado 2014

Reactivity and Chemoselectivity of Allenes in Rh(I)-Catalyzed Intermolecular (5 + 2) Cycloadditions with Vinylcyclopropanes: Allene-Mediated Rhodacycle Formation Can Poison Rh(I)-C...

por Hong, Xin, Stevens, Matthew C., Liu, Peng, Wender, Paul A., Houk, K. N.
Publicado 2014

Structural Complexity Through Multicomponent Cycloaddition Cascades Enabled by Dual-Purpose, Reactivity Regenerating 1,2,3-Triene Equivalents

por Wender, Paul A., Fournogerakis, Dennis N., Jeffreys, Matthew S., Quiroz, Ryan V., Inagaki, Fuyuhiko, Pfaffenbach, Magnus
Publicado 2014

Circular RNA vaccine induces potent T cell responses

por Amaya, Laura, Grigoryan, Lilit, Li, Zhijian, Lee, Audrey, Wender, Paul A., Pulendran, Bali, Chang, Howard Y.
Publicado 2023

Secreted factors induced by PKC modulators do not indirectly cause HIV latency reversal

por Moran, Jose A., Ranjan, Alok, Hourani, Rami, Kim, Jocelyn T., Wender, Paul A., Zack, Jerome A., Marsden, Matthew D.
Publicado 2023

Designed, Synthetically Accessible Bryostatin Analogues Potently Induce Activation of Latent HIV Reservoirs in vitro

por DeChristopher, Brian A., Loy, Brian A., Marsden, Matthew D., Schrier, Adam J., Zack, Jerome A., Wender, Paul A.
Publicado 2012

Reversible RNA acylation for control of CRISPR–Cas9 gene editing

por Habibian, Maryam, McKinlay, Colin, Blake, Timothy R., Kietrys, Anna M., Waymouth, Robert M., Wender, Paul A., Kool, Eric T.
Publicado 2019

Delivery of Inorganic Polyphosphate into Cells Using Amphipathic Oligocarbonate Transporters

por Fernandes-Cunha, Gabriella M., McKinlay, Colin J., Vargas, Jessica R., Jessen, Henning J., Waymouth, Robert M., Wender, Paul A.
Publicado 2018

Synthesis and mechanistic investigations of pH-responsive cationic poly(aminoester)s

por Blake, Timothy R., Ho, Wilson C., Turlington, Christopher R., Zang, Xiaoyu, Huttner, Melanie A., Wender, Paul A., Waymouth, Robert M.
Publicado 2020

Function through bio-inspired, synthesis-informed design: step-economical syntheses of designed kinase inhibitors

por Wender, Paul A., Axtman, Alison D., Golden, Jennifer E., Kee, Jung-Min, Sirois, Lauren E., Quiroz, Ryan V., Stevens, Matthew C.
Publicado 2014

Retrosynthetic Reaction Prediction Using Neural Sequence-to-Sequence Models

por Liu, Bowen, Ramsundar, Bharath, Kawthekar, Prasad, Shi, Jade, Gomes, Joseph, Luu Nguyen, Quang, Ho, Stephen, Sloane, Jack, Wender, Paul, Pande, Vijay
Publicado 2017

A Gateway Synthesis, PKC Affinities and Cell Growth Activities of Daphnane Congeners

por Wender, Paul A., Buschmann, Nicole, Cardin, Nathan B., Jones, Lisa R., Kan, Cindy, Kee, Jung-Min, Kowalski, John A., Longcore, Kate E.
Publicado 2011