CRIS: complete reconstruction of immunoglobulin V-D-J sequences from RNA-seq data

por Islam, Rashedul, Bilenky, Misha, Weng, Andrew P, Connors, Joseph M, Hirst, Martin
Publicado 2021

IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias

por Gusscott, Samuel, Jenkins, Catherine E., Lam, Sonya H., Giambra, Vincenzo, Pollak, Michael, Weng, Andrew P.
Publicado 2016

Defining the clonality of peripheral T cell lymphomas using RNA-seq

por Brown, Scott D, Hapgood, Greg, Steidl, Christian, Weng, Andrew P, Savage, Kerry J, Holt, Robert A
Publicado 2017

RUNX1 colludes with NOTCH1 to reprogram chromatin in T cell acute lymphoblastic leukemia

por Islam, Rashedul, Jenkins, Catherine E., Cao, Qi, Wong, Jasper, Bilenky, Misha, Carles, Annaïck, Moksa, Michelle, Weng, Andrew P., Hirst, Martin
Publicado 2023

SpatialSort: a Bayesian model for clustering and cell population annotation of spatial proteomics data

por Lee, Eric, Chern, Kevin, Nissen, Michael, Wang, Xuehai, Huang, Chris, Gandhi, Anita K, Bouchard-Côté, Alexandre, Weng, Andrew P, Roth, Andrew
Publicado 2023

PKCθ Regulates T-Cell Leukemia-Initiating Activity via Reactive Oxygen Species

por Giambra, Vincenzo, Jenkins, Christopher R., Wang, Hongfang, Lam, Sonya H., Shevchuk, Olena O., Nemirovsky, Oksana, Wai, Carol, Gusscott, Sam, Chiang, Mark Y., Aster, Jon C., Humphries, R. Keith, Eaves, Connie, Weng, Andrew P.
Publicado 2012

High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling

por Medyouf, Hind, Gusscott, Samuel, Wang, Hongfang, Tseng, Jen-Chieh, Wai, Carol, Nemirovsky, Oksana, Trumpp, Andreas, Pflumio, Francoise, Carboni, Joan, Gottardis, Marco, Pollak, Michael, Kung, Andrew L., Aster, Jon C., Holzenberger, Martin, Weng, Andrew P.
Publicado 2011

Molecular etiology of an indolent lymphoproliferative disorder determined by whole-genome sequencing

por Parker, Jeremy D.K., Shen, Yaoqing, Pleasance, Erin, Li, Yvonne, Schein, Jacqueline E., Zhao, Yongjun, Moore, Richard, Wegrzyn-Woltosz, Joanna, Savage, Kerry J., Weng, Andrew P., Gascoyne, Randy D., Jones, Steven, Marra, Marco, Laskin, Janessa, Karsan, Aly
Publicado 2016

Noncanonical β-catenin interactions promote leukemia-initiating activity in early T-cell acute lymphoblastic leukemia

por Panelli, Patrizio, De Santis, Elisabetta, Colucci, Mattia, Tamiro, Francesco, Sansico, Francesca, Miroballo, Mattia, Murgo, Emanuele, Padovano, Costanzo, Gusscott, Sam, Ciavarella, Michele, Chavez, Elizabeth A., Bianchi, Fabrizio, Rossi, Giovanni, Carella, Angelo M., Steidl, Christian, Weng, Andrew P., Giambra, Vincenzo
Publicado 2023

Cell Fate Decisions in Malignant Hematopoiesis: Leukemia Phenotype Is Determined by Distinct Functional Domains of the MN1 Oncogene

por Lai, Courteney K., Moon, Yeonsook, Kuchenbauer, Florian, Starzcynowski, Daniel T., Argiropoulos, Bob, Yung, Eric, Beer, Philip, Schwarzer, Adrian, Sharma, Amit, Park, Gyeongsin, Leung, Malina, Lin, Grace, Vollett, Sarah, Fung, Stephen, Eaves, Connie J., Karsan, Aly, Weng, Andrew P., Humphries, R. Keith, Heuser, Michael
Publicado 2014

Single-cell profiling reveals the importance of CXCL13/CXCR5 axis biology in lymphocyte-rich classic Hodgkin lymphoma

por Aoki, Tomohiro, Chong, Lauren C., Takata, Katsuyoshi, Milne, Katy, Marshall, Ashley, Chavez, Elizabeth A., Miyata-Takata, Tomoko, Ben-Neriah, Susana, Unrau, Doria, Telenius, Adele, Boyle, Merrill, Weng, Andrew P., Savage, Kerry J., Scott, David W., Farinha, Pedro, Shah, Sohrab P., Nelson, Brad H., Steidl, Christian
Publicado 2021

Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL

por Antoszewski, Mateusz, Fournier, Nadine, Ruiz Buendía, Gustavo A., Lourenco, Joao, Liu, Yuanlong, Sugrue, Tara, Dubey, Christelle, Nkosi, Marianne, Pritchard, Colin E.J., Huijbers, Ivo J., Segat, Gabriela C., Alonso-Moreno, Sandra, Serracanta, Elisabeth, Belver, Laura, Ferrando, Adolfo A., Ciriello, Giovanni, Weng, Andrew P., Koch, Ute, Radtke, Freddy
Publicado 2022

Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia

por Kusakabe, Manabu, Sun, Ann Chong, Tyshchenko, Kateryna, Wong, Rachel, Nanda, Aastha, Shanna, Claire, Gusscott, Samuel, Chavez, Elizabeth A., Lorzadeh, Alireza, Zhu, Alice, Hill, Ainsleigh, Hung, Stacy, Brown, Scott, Babaian, Artem, Wang, Xuehai, Holt, Robert A., Steidl, Christian, Karsan, Aly, Humphries, R. Keith, Eaves, Connie J., Hirst, Martin, Weng, Andrew P.
Publicado 2019

Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia

por Pouliot, Gayle P., Degar, James, Hinze, Laura, Kochupurakkal, Bose, Vo, Chau D., Burns, Melissa A., Moreau, Lisa, Ganesa, Chirag, Roderick, Justine, Peirs, Sofie, Menten, Bjorn, Loh, Mignon L., Hunger, Stephen P., Silverman, Lewis B., Harris, Marian H., Stevenson, Kristen E., Weinstock, David M., Weng, Andrew P., Van Vlierberghe, Pieter, D’Andrea, Alan D., Gutierrez, Alejandro
Publicado 2019

Regulation of PI3K signaling in T cell acute lymphoblastic leukemia: a novel PTEN/Ikaros/miR-26b mechanism reveals a critical targetable role for PIK3CD

por Yuan, Tian, Yang, Yaling, Chen, Jiayu, Li, Wenhui, Li, Wuping, Zhang, Qi, Mi, Yingchang, Goswami, Rashmi S., You, Jeffrey Q., Lin, Daniel, Qian, M. Diana, Calin, Steliana, Liang, Yong, Miranda, Roberto N., Calin, George A., Zhou, Xiaoyan, Ma, Li, Zweidler-McKay, Patrick A., Liu, Bin, Weng, Andrew P., Medeiros, L. Jeffrey, Zhang, Yizhuo, You, M. James
Publicado 2017

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

por Kwiatkowski, Nicholas, Zhang, Tinghu, Rahl, Peter B, Abraham, Brian J, Reddy, Jessica, Ficarro, Scott B, Dastur, Anahita, Amzallag, Arnaud, Ramaswamy, Sridhar, Tesar, Bethany, Jenkins, Christopher R, Hannett, Nancy M, McMillin, Douglas, Sanda, Takaomi, Sim, Taebo, Kim, Nam Doo, Look, Thomas, Mitsiades, Constantine, Weng, Andrew P, Brown, Jennifer R, Benes, Cyril H., Marto, Jarrod A, Young, Richard A, Gray, Nathanael S.
Publicado 2014

Single-cell profiling reveals a memory B cell-like subtype of follicular lymphoma with increased transformation risk

por Wang, Xuehai, Nissen, Michael, Gracias, Deanne, Kusakabe, Manabu, Simkin, Guillermo, Jiang, Aixiang, Duns, Gerben, Sarkozy, Clementine, Hilton, Laura, Chavez, Elizabeth A., Segat, Gabriela C., Wong, Rachel, Kim, Jubin, Aoki, Tomohiro, Islam, Rashedul, May, Christina, Hung, Stacy, Tyshchenko, Kate, Brinkman, Ryan R., Hirst, Martin, Karsan, Aly, Freeman, Ciara, Sehn, Laurie H., Morin, Ryan D., Roth, Andrew J., Savage, Kerry J., Craig, Jeffrey W., Shah, Sohrab P., Steidl, Christian, Scott, David W., Weng, Andrew P.
Publicado 2022