Heteronuclear transverse and longitudinal relaxation in AX(4) spin systems: Application to (15)N relaxations in (15)NH(4)(+)

por Werbeck, Nicolas D., Hansen, D. Flemming
Publicado 2014

Probing Arginine Side-Chains and Their Dynamics with Carbon-Detected NMR Spectroscopy: Application to the 42 kDa Human Histone Deacetylase 8 at High pH**

por Werbeck, Nicolas D, Kirkpatrick, John, Hansen, D Flemming
Publicado 2013

Using (15)N-Ammonium to Characterise and Map Potassium Binding Sites in Proteins by NMR Spectroscopy

por Werbeck, Nicolas D, Kirkpatrick, John, Reinstein, Jochen, Hansen, D Flemming
Publicado 2014

Characterizing Active Site Conformational Heterogeneity along the Trajectory of an Enzymatic Phosphoryl Transfer Reaction

por Zeymer, Cathleen, Werbeck, Nicolas D., Zimmermann, Sabine, Reinstein, Jochen, Hansen, D. Flemming
Publicado 2016

Elements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motor

por Zeymer, Cathleen, Barends, Thomas R. M., Werbeck, Nicolas D., Schlichting, Ilme, Reinstein, Jochen
Publicado 2014

Loop Interactions and Dynamics Tune the Enzymatic Activity of the Human Histone Deacetylase 8

por Kunze, Micha B. A., Wright, David W., Werbeck, Nicolas D., Kirkpatrick, John, Coveney, Peter V., Hansen, D. Flemming
Publicado 2013

Characterization of the Menin-MLL Interaction as Therapeutic Cancer Target

por Brzezinka, Krzysztof, Nevedomskaya, Ekaterina, Lesche, Ralf, Haegebarth, Andrea, ter Laak, Antonius, Fernández-Montalván, Amaury E., Eberspaecher, Uwe, Werbeck, Nicolas D., Moenning, Ursula, Siegel, Stephan, Haendler, Bernard, Eheim, Ashley L., Stresemann, Carlo
Publicado 2020

A distal regulatory region of a class I human histone deacetylase

por Werbeck, Nicolas D., Shukla, Vaibhav Kumar, Kunze, Micha B. A., Yalinca, Havva, Pritchard, Ruth B., Siemons, Lucas, Mondal, Somnath, Greenwood, Simon O. R., Kirkpatrick, John, Marson, Charles M., Hansen, D. Flemming
Publicado 2020

Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction

por Hillig, Roman C., Sautier, Brice, Schroeder, Jens, Moosmayer, Dieter, Hilpmann, André, Stegmann, Christian M., Werbeck, Nicolas D., Briem, Hans, Boemer, Ulf, Weiske, Joerg, Badock, Volker, Mastouri, Julia, Petersen, Kirstin, Siemeister, Gerhard, Kahmann, Jan D., Wegener, Dennis, Böhnke, Niels, Eis, Knut, Graham, Keith, Wortmann, Lars, von Nussbaum, Franz, Bader, Benjamin
Publicado 2019