Cytoplasmic Relocalization of TAR DNA-Binding Protein 43 Is Not Sufficient to Reproduce Cellular Pathologies Associated with ALS In vitro

por Wobst, Heike J., Wesolowski, Steven S., Chadchankar, Jayashree, Delsing, Louise, Jacobsen, Steven, Mukherjee, Jayanta, Deeb, Tarek Z., Dunlop, John, Brandon, Nicholas J., Moss, Stephen J.
Publicado 2017

Synthetic Analogues of Huwentoxin-IV Spider Peptide With Altered Human Na(V)1.7/Na(V)1.6 Selectivity Ratios

por Lopez, Ludivine, Montnach, Jérôme, Oliveira-Mendes, Barbara, Khakh, Kuldip, Thomas, Baptiste, Lin, Sophia, Caumes, Cécile, Wesolowski, Steven, Nicolas, Sébastien, Servent, Denis, Cohen, Charles, Béroud, Rémy, Benoit, Evelyne, De Waard, Michel
Publicado 2021

NBI-921352, a first-in-class, Na(V)1.6 selective, sodium channel inhibitor that prevents seizures in Scn8a gain-of-function mice, and wild-type mice and rats

por Johnson, JP, Focken, Thilo, Khakh, Kuldip, Tari, Parisa Karimi, Dube, Celine, Goodchild, Samuel J, Andrez, Jean-Christophe, Bankar, Girish, Bogucki, David, Burford, Kristen, Chang, Elaine, Chowdhury, Sultan, Dean, Richard, de Boer, Gina, Decker, Shannon, Dehnhardt, Christoph, Feng, Mandy, Gong, Wei, Grimwood, Michael, Hasan, Abid, Hussainkhel, Angela, Jia, Qi, Lee, Stephanie, Li, Jenny, Lin, Sophia, Lindgren, Andrea, Lofstrand, Verner, Mezeyova, Janette, Namdari, Rostam, Nelkenbrecher, Karen, Shuart, Noah Gregory, Sojo, Luis, Sun, Shaoyi, Taron, Matthew, Waldbrook, Matthew, Weeratunge, Diana, Wesolowski, Steven, Williams, Aaron, Wilson, Michael, Xie, Zhiwei, Yoo, Rhena, Young, Clint, Zenova, Alla, Zhang, Wei, Cutts, Alison J, Sherrington, Robin P, Pimstone, Simon N, Winquist, Raymond, Cohen, Charles J, Empfield, James R
Publicado 2022