Response to anti-IL17 therapy in inflammatory disease is not strongly impacted by genetic background

por Zhang, Cong, Shestopaloff, Konstantin, Hollis, Benjamin, Kwok, Chun Hei, Hon, Claudia, Hartmann, Nicole, Tian, Chengeng, Wozniak, Magdalena, Santos, Luis, West, Dominique, Gardiner, Stephen, Mallon, Ann-Marie, Readie, Aimee, Martin, Ruvie, Nichols, Thomas, Beste, Michael T., Zierer, Jonas, Ferrero, Enrico, Vandemeulebroecke, Marc, Jostins-Dean, Luke
Publicado 2023

Advancing data science in drug development through an innovative computational framework for data sharing and statistical analysis

por Mallon, Ann-Marie, Häring, Dieter A., Dahlke, Frank, Aarden, Piet, Afyouni, Soroosh, Delbarre, Daniel, El Emam, Khaled, Ganjgahi, Habib, Gardiner, Stephen, Kwok, Chun Hei, West, Dominique M., Straiton, Ewan, Haemmerle, Sibylle, Huffman, Adam, Hofmann, Tom, Kelly, Luke J., Krusche, Peter, Laramee, Marie-Claude, Lheritier, Karine, Ligozio, Greg, Readie, Aimee, Santos, Luis, Nichols, Thomas E., Branson, Janice, Holmes, Chris
Publicado 2021

Large scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy

por Tadros, Rafik, Zheng, Sean L, Grace, Christopher, Jordà, Paloma, Francis, Catherine, Jurgens, Sean J, Thomson, Kate L, Harper, Andrew R, Ormondroyd, Elizabeth, West, Dominique M, Xu, Xiao, Theotokis, Pantazis I, Buchan, Rachel J, McGurk, Kathryn A, Mazzarotto, Francesco, Boschi, Beatrice, Pelo, Elisabetta, Lee, Michael, Noseda, Michela, Varnava, Amanda, Vermeer, Alexa MC, Walsh, Roddy, Amin, Ahmad S, van Slegtenhorst, Marjon A, Roslin, Nicole, Strug, Lisa J, Salvi, Erika, Lanzani, Chiara, de Marvao, Antonio, Roberts, Jason D, Tremblay-Gravel, Maxime, Giraldeau, Genevieve, Cadrin-Tourigny, Julia, L'Allier, Philippe L, Garceau, Patrick, Talajic, Mario, Pinto, Yigal M, Rakowski, Harry, Pantazis, Antonis, Baksi, John, Halliday, Brian P, Prasad, Sanjay K, Barton, Paul JR, O'Regan, Declan P, Cook, Stuart A, de Boer, Rudolf A, Christiaans, Imke, Michels, Michelle, Kramer, Christopher M, Ho, Carolyn Y, Neubauer, Stefan, Matthews, Paul M, Wilde, Arthur A, Tardif, Jean-Claude, Olivotto, Iacopo, Adler, Arnon, Goel, Anuj, Ware, James S, Bezzina, Connie R, Watkins, Hugh
Publicado 2023