Ubiquitin chains: a new way of screening for regulatory differences in pulmonary hypertension

por Rathinasabapathy, Anandharajan, West, James D.
Publicado 2018

The yeast Hsp70 Ssa1 is a sensor for activation of the heat shock response by thiol-reactive compounds

por Wang, Yanyu, Gibney, Patrick A., West, James D., Morano, Kevin A.
Publicado 2012

Myeloid-Derived Suppressor Cells and Pulmonary Hypertension

por Bryant, Andrew J., Mehrad, Borna, Brusko, Todd M., West, James D., Moldawer, Lyle L.
Publicado 2018

Urm1, not quite a ubiquitin-like modifier?

por Kaduhr, Lars, Brachmann, Cindy, Ravichandran, Keerthiraju Ethiraju, West, James D., Glatt, Sebastian, Schaffrath, Raffael
Publicado 2021

Piecing Together How Peroxiredoxins Maintain Genomic Stability

por West, James D., Roston, Trevor J., David, Joseph B., Allan, Kristin M., Loberg, Matthew A.
Publicado 2018

Redox requirements for ubiquitin-like urmylation of Ahp1, a 2-Cys peroxiredoxin from yeast

por Brachmann, Cindy, Kaduhr, Lars, Jüdes, André, Ravichandran, Keerthiraju Ethiraju, West, James D., Glatt, Sebastian, Schaffrath, Raffael
Publicado 2020

A disease-associated frameshift mutation in caveolin-1 disrupts caveolae formation and function through introduction of a de novo ER retention signal

por Copeland, Courtney A., Han, Bing, Tiwari, Ajit, Austin, Eric D., Loyd, James E., West, James D., Kenworthy, Anne K.
Publicado 2017

rhACE2 Therapy Modifies Bleomycin-Induced Pulmonary Hypertension via Rescue of Vascular Remodeling

por Rathinasabapathy, Anandharajan, Bryant, Andrew J., Suzuki, Toshio, Moore, Christy, Shay, Sheila, Gladson, Santhi, West, James D., Carrier, Erica J.
Publicado 2018

Pulmonary Vascular Platform Models the Effects of Flow and Pressure on Endothelial Dysfunction in BMPR2 Associated Pulmonary Arterial Hypertension

por D’Amico, Reid W., Faley, Shannon, Shim, Ha-na, Prosser, Joanna R., Agrawal, Vineet, Bellan, Leon M., West, James D.
Publicado 2018

Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7

por Nguyen, Thuy T., Caito, Samuel W., Zackert, William E., West, James D., Zhu, Shijun, Aschner, Michael, Fessel, Joshua P., Roberts, L. Jackson
Publicado 2016

Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming

por Fessel, Joshua P., Hamid, Rizwan, Wittmann, Bryan M., Robinson, Linda J., Blackwell, Tom, Tada, Yuji, Tanabe, Nobuhiro, Tatsumi, Koichiro, Hemnes, Anna R., West, James D.
Publicado 2012

Pulmonary vascular effect of insulin in a rodent model of pulmonary arterial hypertension

por Trammell, Aaron W., Talati, Megha, Blackwell, Thomas R., Fortune, Niki L., Niswender, Kevin D., Fessel, Joshua P., Newman, John H., West, James D., Hemnes, Anna R.
Publicado 2017

Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension

por West, James D., Carrier, Erica J., Bloodworth, Nathaniel C., Schroer, Alison K., Chen, Peter, Ryzhova, Larisa M., Gladson, Santhi, Shay, Sheila, Hutcheson, Joshua D., Merryman, W. David
Publicado 2016

Differential IL-1 signaling induced by BMPR2 deficiency drives pulmonary vascular remodeling

por Pickworth, Josephine, Rothman, Alexander, Iremonger, James, Casbolt, Helen, Hopkinson, Kay, Hickey, Peter M., Gladson, Santhi, Shay, Sheila, Morrell, Nicholas W., Francis, Sheila E., West, James D., Lawrie, Allan
Publicado 2017

l‐Carnitine therapy improves right heart dysfunction through Cpt1‐dependent fatty acid oxidation

por Agrawal, Vineet, Hemnes, Anna R., Shelburne, Nicholas J., Fortune, Niki, Fuentes, Julio L., Colvin, Dan, Calcutt, Marion W., Talati, Megha, Poovey, Emily, West, James D., Brittain, Evan L.
Publicado 2022

A multifaceted investigation into molecular associations of chronic thromboembolic pulmonary hypertension pathogenesis

por Halliday, Stephen J, Matthews, Daniel T, Talati, Megha H, Austin, Eric D, Su, Yan R, Absi, Tarek S, Fortune, Niki L, Gailani, David, Matafonov, Anton, West, James D, Hemnes, Anna R
Publicado 2020

Low-grade albuminuria in pulmonary arterial hypertension

por Nickel, Nils P., de Jesus Perez, Vinicio A., Zamanian, Roham T., Fessel, Joshua P., Cogan, Joy D., Hamid, Rizwam, West, James D., de Caestecker, Mark P., Yang, Haichun, Austin, Eric D.
Publicado 2019

Natriuretic peptide receptor C contributes to disproportionate right ventricular hypertrophy in a rodent model of obesity-induced heart failure with preserved ejection fraction wit...

por Agrawal, Vineet, Fortune, Niki, Yu, Sheeline, Fuentes, Julio, Shi, Fubiao, Nichols, David, Gleaves, Linda, Poovey, Emily, Wang, Thomas J., Brittain, Evan L., Collins, Sheila, West, James D., Hemnes, Anna R.
Publicado 2019

Expression of a Human Caveolin-1 Mutation in Mice Drives Inflammatory and Metabolic Defect-Associated Pulmonary Arterial Hypertension

por Rathinasabapathy, Anandharajan, Copeland, Courtney, Crabtree, Amber, Carrier, Erica J., Moore, Christy, Shay, Sheila, Gladson, Santhi, Austin, Eric D., Kenworthy, Anne K., Loyd, James E., Hemnes, Anna R., West, James D.
Publicado 2020

Antagonism of the Thromboxane‐Prostanoid Receptor as a Potential Therapy for Cardiomyopathy of Muscular Dystrophy

por West, James D., Galindo, Cristi L., Kim, Kyungsoo, Shin, John Jonghyun, Atkinson, James B., Macias‐Perez, Ines, Pavliv, Leo, Knollmann, Bjorn C., Soslow, Jonathan H., Markham, Larry W., Carrier, Erica J.
Publicado 2019