Classification of Parkinson’s Disease Genotypes in Drosophila Using Spatiotemporal Profiling of Vision

por West, Ryan J.H., Elliott, Christopher J.H., Wade, Alex R.
Publicado 2015

The pro-apoptotic JNK scaffold POSH/SH3RF1 mediates CHMP2B(Intron5)-associated toxicity in animal models of frontotemporal dementia

por West, Ryan J H, Ugbode, Chris, Gao, Fen-Biao, Sweeney, Sean T
Publicado 2018

Neuroprotective activity of ursodeoxycholic acid in CHMP2B(Intron5) models of frontotemporal dementia

por West, Ryan J.H., Ugbode, Chris, Fort-Aznar, Laura, Sweeney, Sean T.
Publicado 2020

Metal-free selective mono-halodecarboxylation of heteroarenes under mild conditions

por Henderson, Scott H., West, Ryan A., Ward, Simon E., Honey, Mark A.
Publicado 2018

Modeling C9orf72-Related Frontotemporal Dementia and Amyotrophic Lateral Sclerosis in Drosophila

por Sharpe, Joanne L., Harper, Nikki S., Garner, Duncan R., West, Ryan J. H.
Publicado 2021

Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia

por West, Ryan J.H., Lu, Yubing, Marie, Bruno, Gao, Fen-Biao, Sweeney, Sean T.
Publicado 2015

Identification of dietary alanine toxicity and trafficking dysfunction in a Drosophila model of hereditary sensory and autonomic neuropathy type 1

por Oswald, Matthew C. W., West, Ryan J. H., Lloyd-Evans, Emyr, Sweeney, Sean T.
Publicado 2015

Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila

por Lu, Yubing, West, Ryan J. H., Pons, Marine, Sweeney, Sean T., Gao, Fen-Biao
Publicado 2020

The tocopherol transfer protein mediates vitamin E trafficking between cerebellar astrocytes and neurons

por Ulatowski, L., Ghelfi, Mikel, West, Ryan, Atkinson, J., Finno, C.J., Manor, D.
Publicado 2022

Neurophysiology of Drosophila Models of Parkinson's Disease

por West, Ryan J. H., Furmston, Rebecca, Williams, Charles A. C., Elliott, Christopher J. H.
Publicado 2015

A perceptive plus in Parkinson's disease

por Himmelberg, Marc M., West, Ryan J.H., Wade, Alex R., Elliott, Christopher J.H.
Publicado 2018

Abnormal visual gain control and excitotoxicity in early-onset Parkinson’s disease Drosophila models

por Himmelberg, Marc M., West, Ryan J. H., Elliott, Christopher J. H., Wade, Alex R.
Publicado 2018

Sphingolipids regulate neuromuscular synapse structure and function in Drosophila

por West, Ryan J. H., Briggs, Laura, Perona Fjeldstad, Maria, Ribchester, Richard R., Sweeney, Sean T.
Publicado 2018

Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila

por West, Ryan J. H., Sharpe, Joanne L., Voelzmann, André, Munro, Anna L., Hahn, Ines, Baines, Richard A., Pickering-Brown, Stuart
Publicado 2020

Autism sensory dysfunction in an evolutionarily conserved system

por Vilidaite, Greta, Norcia, Anthony M., West, Ryan J. H., Elliott, Christopher J. H., Pei, Francesca, Wade, Alex R., Baker, Daniel H.
Publicado 2018

Reactive oxygen species regulate activity-dependent neuronal plasticity in Drosophila

por Oswald, Matthew CW, Brooks, Paul S, Zwart, Maarten F, Mukherjee, Amrita, West, Ryan JH, Giachello, Carlo NG, Morarach, Khomgrit, Baines, Richard A, Sweeney, Sean T, Landgraf, Matthias
Publicado 2018

African trypanosomiasis: Synthesis & SAR enabling novel drug discovery of ubiquinol mimics for trypanosome alternative oxidase

por West, Ryan A., O'Doherty, Oran G., Askwith, Trevor, Atack, John, Beswick, Paul, Laverick, Jamie, Paradowski, Michael, Pennicott, Lewis E., Rao, Srinivasa P.S., Williams, Gareth, Ward, Simon E.
Publicado 2017

Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity

por Bennett, Craig L., Dastidar, Somasish, Arnold, Frederick J., McKinstry, Spencer U., Stockford, Cameron, Freibaum, Brian D., Sopher, Bryce L., Wu, Meilin, Seidner, Glen, Joiner, William, Taylor, J. Paul, West, Ryan J. H., La Spada, Albert R.
Publicado 2023