KLIFS: an overhaul after the first 5 years of supporting kinase research

por Kanev, Georgi K, de Graaf, Chris, Westerman, Bart A, de Esch, Iwan J P, Kooistra, Albert J
Publicado 2020

Longitudinal drug synergy assessment using convolutional neural network image-decoding of glioblastoma single-spheroid cultures

por Giczewska, Anna, Pastuszak, Krzysztof, Houweling, Megan, Abdul, Kulsoom U, Faaij, Noa, Wedekind, Laurine, Noske, David, Wurdinger, Thomas, Supernat, Anna, Westerman, Bart A
Publicado 2023

Predicting the target landscape of kinase inhibitors using 3D convolutional neural networks

por Kanev, Georgi K., Zhang, Yaran, Kooistra, Albert J., Bender, Andreas, Leurs, Rob, Bailey, David, Würdinger, Thomas, de Graaf, Chris, de Esch, Iwan J. P., Westerman, Bart A.
Publicado 2023

Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions

por Lameris, Roeland, Shahine, Adam, Veth, Myrthe, Westerman, Bart, Godfrey, Dale I, Lutje Hulsik, David, Brouwer, Patricia, Rossjohn, Jamie, de Gruijl, Tanja D, van der Vliet, Hans J
Publicado 2023

The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures

por Narayan, Ravi S., Fedrigo, Carlos A., Brands, Eelke, Dik, Rogier, Stalpers, Lukas J.A., Baumert, Brigitta G., Slotman, Ben J., Westerman, Bart A., Peters, Godefridus J., Sminia, Peter
Publicado 2017

Data-driven prioritization and preclinical evaluation of therapeutic targets in glioblastoma

por Brahm, Cyrillo G, Abdul, U Kulsoom, Houweling, Megan, van Linde, Myra E, Lagerweij, Tonny, Verheul, Henk M W, Westerman, Bart A, Walenkamp, Annemiek M E, Fehrmann, Rudolf S N
Publicado 2020

CXCR4 expression in glioblastoma tissue and the potential for PET imaging and treatment with [(68)Ga]Ga-Pentixafor /[(177)Lu]Lu-Pentixather

por Jacobs, Sarah M., Wesseling, Pieter, de Keizer, Bart, Tolboom, Nelleke, Ververs, F. F. Tessa, Krijger, Gerard C., Westerman, Bart A., Snijders, Tom J., Robe, Pierre A., van der Kolk, Anja G.
Publicado 2021

Screening of predicted synergistic multi-target therapies in glioblastoma identifies new treatment strategies

por Houweling, Megan, Giczewska, Anna, Abdul, Kulsoom, Nieuwenhuis, Ninke, Küçükosmanoglu, Asli, Pastuszak, Krzysztof, Buijsman, Rogier C, Wesseling, Pieter, Wedekind, Laurine, Noske, David, Supernat, Anna, Bailey, David, Watts, Colin, Wurdinger, Thomas, Westerman, Bart A
Publicado 2023

GFAP-Cre-Mediated Transgenic Activation of Bmi1 Results in Pituitary Tumors

por Westerman, Bart A., Blom, Marleen, Tanger, Ellen, van der Valk, Martin, Song, Ji-Ying, van Santen, Marije, Gadiot, Jules, Cornelissen-Steijger, Paulien, Zevenhoven, John, Prosser, Haydn M., Uren, Anthony, Aronica, Eleonora, van Lohuizen, Maarten
Publicado 2012

miR-129-3p controls centrosome number in metastatic prostate cancer cells by repressing CP110

por Bijnsdorp, Irene V., Hodzic, Jasmina, Lagerweij, Tonny, Westerman, Bart, Krijgsman, Oscar, Broeke, Jurjen, Verweij, Frederik, Nilsson, R. Jonas A., Rozendaal, Lawrence, van Beusechem, Victor W., van Moorselaar, Jeroen A., Wurdinger, Thomas, Geldof, Albert A.
Publicado 2016

P120-catenin dependent collective brain infiltration by glioma cell networks

por Gritsenko, Pavlo G., Atlasy, Nader, Dieteren, Cindy E.J., Navis, Anna C., Venhuizen, Jan-Hendrik, Veelken, Cornelia, Schubert, Dirk, Acker-Palmer, Amparo, Westerman, Bart A., Wurdinger, Thomas, Leenders, William, Wesseling, Pieter, Stunnenberg, Hendrik G., Friedl, Peter
Publicado 2020

A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation

por Westerman, Bart A., Braat, A. Koen, Taub, Nicole, Potman, Marko, Vissers, Joseph H.A., Blom, Marleen, Verhoeven, Els, Stoop, Hans, Gillis, Ad, Velds, Arno, Nijkamp, Wouter, Beijersbergen, Roderick, Huber, Lukas A., Looijenga, Leendert H.J., van Lohuizen, Maarten
Publicado 2011

RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

por Best, Myron G., Sol, Nik, Kooi, Irsan, Tannous, Jihane, Westerman, Bart A., Rustenburg, François, Schellen, Pepijn, Verschueren, Heleen, Post, Edward, Koster, Jan, Ylstra, Bauke, Ameziane, Najim, Dorsman, Josephine, Smit, Egbert F., Verheul, Henk M., Noske, David P., Reijneveld, Jaap C., Nilsson, R. Jonas A., Tannous, Bakhos A., Wesseling, Pieter, Wurdinger, Thomas
Publicado 2015

Longitudinal characteristics of T2-FLAIR mismatch in IDH-mutant astrocytomas: Relation to grade, histopathology, and overall survival in the GLASS-NL cohort

por van Garderen, Karin A, Vallentgoed, Wies R, Lavrova, Anna, Niers, Johanna M, de Leng, Wendy W J, Hoogstrate, Youri, de Heer, Iris, Ylstra, Bauke, van Dijk, Erik, Klein, Stefan, Draaisma, Kaspar, Robe, Pierre A J T, Verhaak, Roel G W, Westerman, Bart A, French, Pim J, van den Bent, Martin J, Kouwenhoven, Mathilde C M, Kros, Johan M, Wesseling, Pieter, Smits, Marion
Publicado 2023

Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8

por Berenguer, Jordi, Lagerweij, Tonny, Zhao, Xi Wen, Dusoswa, Sophie, van der Stoop, Petra, Westerman, Bart, de Gooijer, Mark C., Zoetemelk, Marloes, Zomer, Anoek, Crommentuijn, Matheus H. W., Wedekind, Laurine E., López-López, Àlan, Giovanazzi, Alberta, Bruch-Oms, Marina, van der Meulen-Muileman, Ida H., Reijmers, Rogier M., van Kuppevelt, Toin H., García-Vallejo, Juan-Jesús, van Kooyk, Yvette, Tannous, Bakhos A., Wesseling, Pieter, Koppers-Lalic, Danijela, Vandertop, W. Peter, Noske, David P., van Beusechem, Victor W., van Rheenen, Jacco, Pegtel, D. Michiel, van Tellingen, Olaf, Wurdinger, Thomas
Publicado 2018

A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities

por Narayan, Ravi S., Molenaar, Piet, Teng, Jian, Cornelissen, Fleur M. G., Roelofs, Irene, Menezes, Renee, Dik, Rogier, Lagerweij, Tonny, Broersma, Yoran, Petersen, Naomi, Marin Soto, Jhon Alexander, Brands, Eelke, van Kuiken, Philip, Lecca, Maria C., Lenos, Kristiaan J., In ‘t Veld, Sjors G. J. G., van Wieringen, Wessel, Lang, Frederick F., Sulman, Erik, Verhaak, Roel, Baumert, Brigitta G., Stalpers, Lucas J. A., Vermeulen, Louis, Watts, Colin, Bailey, David, Slotman, Ben J., Versteeg, Rogier, Noske, David, Sminia, Peter, Tannous, Bakhos A., Wurdinger, Tom, Koster, Jan, Westerman, Bart A.
Publicado 2020

LONGITUDINAL MOLECULAR TRAJECTORIES OF DIFFUSE GLIOMA IN ADULTS

por Barthel, Floris P., Johnson, Kevin C., Varn, Frederick S., Moskalik, Anzhela D., Tanner, Georgette, Kocakavuk, Emre, Anderson, Kevin J., Abiola, Olajide, Aldape, Kenneth, Alfaro, Kristin D., Alpar, Donat, Amin, Samirkumar B., Ashley, David M., Bandopadhayay, Pratiti, Barnholtz-Sloan, Jill S., Beroukhim, Rameen, Bock, Christoph, Brastianos, Priscilla K., Brat, Daniel J., Brodbelt, Andrew R., Bruns, Alexander F., Bulsara, Ketan R., Chakrabarty, Aruna, Chakravarti, Arnab, Chuang, Jeffrey H., Claus, Elizabeth B., Cochran, Elizabeth J., Connelly, Jennifer, Costello, Joseph F., Finocchiaro, Gaetano, Fletcher, Michael N., French, Pim J., Gan, Hui K., Gilbert, Mark R., Gould, Peter V., Grimmer, Matthew R., Iavarone, Antonio, Ismail, Azzam, Jenkinson, Michael D., Khasraw, Mustafa, Kim, Hoon, Kouwenhoven, Mathilde C.M., LaViolette, Peter S., Li, Meihong, Lichter, Peter, Ligon, Keith L., Lowman, Allison K., Malta, Tathiane M., Mazor, Tali, McDonald, Kerrie L., Molinaro, Annette M., Nam, Do-Hyun, Nayyar, Naema, Ng, Ho Keung, Ngan, Chew Yee, Niclou, Simone, P., Niers, Johanna M., Noushmehr, Houtan, Noorbakhsh, Javad, Ormond, D. Ryan, Park, Chul-Kee, Poisson, Laila M., Rabadan, Raul, Radlwimmer, Bernhard, Rao, Ganesh, Reifenberger, Guido, Sa, Jason K., Schuster, Michael, Shaw, Brian L., Short, Susan C., Sillevis Smitt, Peter A., Sloan, Andrew E., Smits, Marion, Suzuki, Hiromichi, Tabatabai, Ghazaleh, Van Meir, Erwin G., Watts, Colin, Weller, Michael, Wesseling, Pieter, Westerman, Bart A., Widhalm, Georg, Woehrer, Adelheid, Alfred Yung, W.K., Zadeh, Gelareh, Huse, Jason T., de Groot, John F., Stead, Lucy F., Verhaak, Roel G.W.
Publicado 2019