Pharmacological inhibition of EZH2 disrupts the female germline epigenome

por Prokopuk, Lexie, Hogg, Kirsten, Western, Patrick S.
Publicado 2018

Out of sight, out of mind? Germ cells and the potential impacts of epigenomic drugs

por Jarred, Ellen G., Bildsoe, Heidi, Western, Patrick S.
Publicado 2018

Identifying disruptors of male germ cell development by small molecule screening in ex vivo gonad cultures

por Wakeling, Stephanie I, Miles, Denise C, Western, Patrick S
Publicado 2013

Technical considerations for genotyping multi-allelic copy number variation (CNV), in regions of segmental duplication

por Cantsilieris, Stuart, Western, Patrick S, Baird, Paul N, White, Stefan J
Publicado 2014

PRC2 is required for extensive reorganization of H3K27me3 during epigenetic reprogramming in mouse fetal germ cells

por Prokopuk, Lexie, Stringer, Jessica M., Hogg, Kirsten, Elgass, Kirstin D., Western, Patrick S.
Publicado 2017

The Impact of Activin A on Fetal Gonocytes: Chronic Versus Acute Exposure Outcomes

por Moody, Sarah C., Whiley, Penny A. F., Western, Patrick S., Loveland, Kate L.
Publicado 2022

FGF-independent MEK1/2 signalling in the developing foetal testis is essential for male germline differentiation in mice

por Blücher, Rheannon O., Lim, Rachel S., Jarred, Ellen G., Ritchie, Matthew E., Western, Patrick S.
Publicado 2023

TIMP-2 regulates proliferation, invasion and STAT3-mediated cancer stem cell-dependent chemoresistance in ovarian cancer cells

por Escalona, Ruth M., Bilandzic, Maree, Western, Patrick, Kadife, Elif, Kannourakis, George, Findlay, Jock K., Ahmed, Nuzhat
Publicado 2020

A novel approach to nonsurgical sterilization; application of menadione‐modified gonocyte‐targeting M13 bacteriophage for germ cell ablation in utero

por Fraser, Barbara A., Miller, Kasey, Trigg, Natalie A., Smith, Nathan D., Western, Patrick S., Nixon, Brett, Aitken, Robert J.
Publicado 2020

Mitotic Arrest in Teratoma Susceptible Fetal Male Germ Cells

por Western, Patrick S., Ralli, Rachael A., Wakeling, Stephanie I., Lo, Camden, van den Bergen, Jocelyn A., Miles, Denise C., Sinclair, Andrew H.
Publicado 2011

Signaling through the TGF Beta-Activin Receptors ALK4/5/7 Regulates Testis Formation and Male Germ Cell Development

por Miles, Denise C., Wakeling, Stephanie I., Stringer, Jessica M., van den Bergen, Jocelyn A., Wilhelm, Dagmar, Sinclair, Andrew H., Western, Patrick S.
Publicado 2013

Loss of maternal EED results in postnatal overgrowth

por Prokopuk, Lexie, Stringer, Jessica M., White, Craig R., Vossen, Rolf H. A. M., White, Stefan J., Cohen, Ana S. A., Gibson, William T., Western, Patrick S.
Publicado 2018

Esrp1 is a marker of mouse fetal germ cells and differentially expressed during spermatogenesis

por Saeidi, Shaghayegh, Shapouri, Farnaz, de Iongh, Robb U., Casagranda, Franca, Sutherland, Jessie M., Western, Patrick S., McLaughlin, Eileen A., Familari, Mary, Hime, Gary R.
Publicado 2018

Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

por Stringer, Jessica M., Forster, Samuel C., Qu, Zhipeng, Prokopuk, Lexie, O’Bryan, Moira K., Gardner, David K., White, Stefan J., Adelson, David, Western, Patrick S.
Publicado 2018

Transient Polycomb activity represses developmental genes in growing oocytes

por Jarred, Ellen G., Qu, Zhipeng, Tsai, Tesha, Oberin, Ruby, Petautschnig, Sigrid, Bildsoe, Heidi, Pederson, Stephen, Zhang, Qing-hua, Stringer, Jessica M., Carroll, John, Gardner, David K., Van den Buuse, Maarten, Sims, Natalie A., Gibson, William T., Adelson, David L., Western, Patrick S.
Publicado 2022

Copy Number Variation in Patients with Disorders of Sex Development Due to 46,XY Gonadal Dysgenesis

por White, Stefan, Ohnesorg, Thomas, Notini, Amanda, Roeszler, Kelly, Hewitt, Jacqueline, Daggag, Hinda, Smith, Craig, Turbitt, Erin, Gustin, Sonja, van den Bergen, Jocelyn, Miles, Denise, Western, Patrick, Arboleda, Valerie, Schumacher, Valerie, Gordon, Lavinia, Bell, Katrina, Bengtsson, Henrik, Speed, Terry, Hutson, John, Warne, Garry, Harley, Vincent, Koopman, Peter, Vilain, Eric, Sinclair, Andrew
Publicado 2011