AAV-p40 Bioengineering Platform for Variant Selection Based on Transgene Expression

por Westhaus, Adrian, Cabanes-Creus, Marti, Jonker, Timo, Sallard, Erwan, Navarro, Renina Gale, Zhu, Erhua, Baltazar Torres, Grober, Lee, Scott, Wilmott, Patrick, Gonzalez-Cordero, Anai, Santilli, Giorgia, Thrasher, Adrian J., Alexander, Ian E., Lisowski, Leszek
Publicado 2022

Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8

por Cabanes-Creus, Marti, Navarro, Renina Gale, Zhu, Erhua, Baltazar, Grober, Liao, Sophia H.Y., Drouyer, Matthieu, Amaya, Anais K., Scott, Suzanne, Nguyen, Loan Hanh, Westhaus, Adrian, Hebben, Matthias, Wilson, Laurence O.W., Thrasher, Adrian J., Alexander, Ian E., Lisowski, Leszek
Publicado 2021

Codon-Optimization of Wild-Type Adeno-Associated Virus Capsid Sequences Enhances DNA Family Shuffling while Conserving Functionality

por Cabanes-Creus, Marti, Ginn, Samantha L., Amaya, Anais K., Liao, Sophia H.Y., Westhaus, Adrian, Hallwirth, Claus V., Wilmott, Patrick, Ward, Jason, Dilworth, Kimberley L., Santilli, Giorgia, Rybicki, Arkadiusz, Nakai, Hiroyuki, Thrasher, Adrian J., Filip, Adrian C., Alexander, Ian E., Lisowski, Leszek
Publicado 2018

High-Throughput In Vitro, Ex Vivo, and In Vivo Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction

por Westhaus, Adrian, Cabanes-Creus, Marti, Rybicki, Arkadiusz, Baltazar, Grober, Navarro, Renina Gale, Zhu, Erhua, Drouyer, Matthieu, Knight, Maddison, Albu, Razvan F., Ng, Boaz H., Kalajdzic, Predrag, Kwiatek, Magdalena, Hsu, Kenneth, Santilli, Giorgia, Gold, Wendy, Kramer, Belinda, Gonzalez-Cordero, Anai, Thrasher, Adrian J., Alexander, Ian E., Lisowski, Leszek
Publicado 2020

Attenuation of Heparan Sulfate Proteoglycan Binding Enhances In Vivo Transduction of Human Primary Hepatocytes with AAV2

por Cabanes-Creus, Marti, Westhaus, Adrian, Navarro, Renina Gale, Baltazar, Grober, Zhu, Erhua, Amaya, Anais K., Liao, Sophia H.Y., Scott, Suzanne, Sallard, Erwan, Dilworth, Kimberley L., Rybicki, Arkadiusz, Drouyer, Matthieu, Hallwirth, Claus V., Bennett, Antonette, Santilli, Giorgia, Thrasher, Adrian J., Agbandje-McKenna, Mavis, Alexander, Ian E., Lisowski, Leszek
Publicado 2020

Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors

por Westhaus, Adrian, Cabanes-Creus, Marti, Dilworth, Kimberley L., Zhu, Erhua, Salas Gómez, David, Navarro, Renina G., Amaya, Anais K., Scott, Suzanne, Kwiatek, Magdalena, McCorkindale, Alexandra L., Hayman, Tara E., Frahm, Silke, Perocheau, Dany P., Tran, Bang Manh, Vincan, Elizabeth, Wong, Sharon L., Waters, Shafagh A., Riddiough, Georgina E., Perini, Marcos V., Wilson, Laurence O.W., Baruteau, Julien, Diecke, Sebastian, González-Aseguinolaza, Gloria, Santilli, Giorgia, Thrasher, Adrian J., Alexander, Ian E., Lisowski, Leszek
Publicado 2023