The Heated Relationship Between Neural Activity and Seizures

por Weston, Matthew C.
Publicado 2020

A tRNA Variant Translates Into Seizure Resistance

por Weston, Matthew C.
Publicado 2021

Glutamate’s Secret Interictal Life

por Cullen, Erin R., Weston, Matthew C.
Publicado 2021

Hyperactivity of mTORC1 or mTORC2-dependent signaling causes epilepsy downstream of somatic PTEN loss

por Cullen, Erin R., Mittelstadt, Isabelle, Weston, Matthew C.
Publicado 2023

Loss of mTOR repressors Tsc1 or Pten has divergent effects on excitatory and inhibitory synaptic transmission in single hippocampal neuron cultures

por Weston, Matthew C., Chen, Hongmei, Swann, John W.
Publicado 2014

Altered Fast Synaptic Transmission in a Mouse Model of DNM1-Associated Developmental Epileptic Encephalopathy

por McCabe, Matthew P., Shore, Amy N., Frankel, Wayne N., Weston, Matthew C.
Publicado 2021

Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neurons

por Shore, Amy N., Qunies, Alshaima’a M., Spitznagel, Brittany D., Weaver, C. David, Emmitte, Kyle A., Frankel, Wayne N., Weston, Matthew C.
Publicado 2023

Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission

por McCabe, Matthew P, Cullen, Erin R, Barrows, Caitlynn M, Shore, Amy N, Tooke, Katherine I, Laprade, Kathryn A, Stafford, James M, Weston, Matthew C
Publicado 2020

Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss

por Tariq, Kamran, Cullen, Erin, Getz, Stephanie A., Conching, Andie K.S., Goyette, Andrew R., Prina, Mackenzi L., Wang, Wei, Li, Meijie, Weston, Matthew C., Luikart, Bryan W.
Publicado 2022

Reduced GABAergic Neuron Excitability, Altered Synaptic Connectivity, and Seizures in a KCNT1 Gain-of-Function Mouse Model of Childhood Epilepsy

por Shore, Amy N., Colombo, Sophie, Tobin, William F., Petri, Sabrina, Cullen, Erin R., Dominguez, Soledad, Bostick, Christopher D., Beaumont, Michael A., Williams, Damian, Khodagholy, Dion, Yang, Mu, Lutz, Cathleen M., Peng, Yueqing, Gelinas, Jennifer N., Goldstein, David B., Boland, Michael J., Frankel, Wayne N., Weston, Matthew C.
Publicado 2020