Molecular action of sulphonylureas on K(ATP) channels: a real partnership between drugs and nucleotides

por de Wet, Heidi, Proks, Peter
Publicado 2015

Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1

por Proks, Peter, de Wet, Heidi, Ashcroft, Frances M.
Publicado 2010

Molecular Mechanism of Sulphonylurea Block of K(ATP) Channels Carrying Mutations That Impair ATP Inhibition and Cause Neonatal Diabetes

por Proks, Peter, de Wet, Heidi, Ashcroft, Frances M.
Publicado 2013

Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A K(ATP) channels: A mechanistic study

por Proks, Peter, de Wet, Heidi, Ashcroft, Frances M.
Publicado 2014

Asymmetric Switching in a Homodimeric ABC Transporter: A Simulation Study

por Aittoniemi, Jussi, de Wet, Heidi, Ashcroft, Frances M., Sansom, Mark S. P.
Publicado 2010

A Ketone Ester Drink Lowers Human Ghrelin and Appetite

por Stubbs, Brianna J., Cox, Pete J., Evans, Rhys D., Cyranka, Malgorzata, Clarke, Kieran, de Wet, Heidi
Publicado 2017

A universally conserved residue in the SUR1 subunit of the K(ATP) channel is essential for translating nucleotide binding at SUR1 into channel opening

por de Wet, Heidi, Shimomura, Kenju, Aittoniemi, Jussi, Ahmad, Nawaz, Lafond, Mathilde, Sansom, Mark SP, Ashcroft, Frances M
Publicado 2012

NMDA Receptor Antagonists Increase the Release of GLP-1 From Gut Endocrine Cells

por Cyranka, Malgorzata, Monfeuga, Thomas, Vedovato, Natascia, Larabee, Chelsea M, Chandran, Anandhakumar, Toledo, Enrique M, de Wet, Heidi
Publicado 2022

Tetrameric structure of SUR2B revealed by electron microscopy of oriented single particles

por Fotinou, Constantina, Aittoniemi, Jussi, Wet, Heidi, Polidori, Ange, Pucci, Bernard, Sansom, Mark S P, Vénien-Bryan, Catherine, Ashcroft, Frances M
Publicado 2013

Acetyl-CoA-carboxylase 1 (ACC1) plays a critical role in glucagon secretion

por Veprik, Anna, Denwood, Geoffrey, Liu, Dong, Bany Bakar, Rula, Morfin, Valentin, McHugh, Kara, Tebeka, Nchimunya N., Vetterli, Laurène, Yonova-Doing, Ekaterina, Gribble, Fiona, Reimann, Frank, Hoehn, Kyle L., Hemsley, Piers A., Ahnfelt-Rønne, Jonas, Rorsman, Patrik, Zhang, Quan, de Wet, Heidi, Cantley, James
Publicado 2022

Disease progression and search for monogenic diabetes among children with new onset type 1 diabetes negative for ICA, GAD- and IA-2 Antibodies

por Pörksen, Sven, Laborie, Lene Bjerke, Nielsen, Lotte, Louise Max Andersen, Marie, Sandal, Tone, de Wet, Heidi, Schwarcz, Erik, Åman, Jan, Swift, Peter, Kocova, Mirjana, Schönle, Eugen J, de Beaufort, Carine, Hougaard, Philip, Ashcroft, Frances, Molven, Anders, Knip, Mikael, Mortensen, Henrik B, Hansen, Lars, Njølstad, Pål R
Publicado 2010

Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP‐1

por Cyranka, Malgorzata, Veprik, Anna, McKay, Eleanor J., van Loon, Nienke, Thijsse, Amber, Cotter, Luke, Hare, Nisha, Saibudeen, Affan, Lingam, Swathi, Pires, Elisabete, Larraufie, Pierre, Reimann, Frank, Gribble, Fiona, Stewart, Michelle, Bentley, Elizabeth, Lear, Pamela, McCullagh, James, Cantley, James, Cox, Roger D., de Wet, Heidi
Publicado 2019